Clinical trials: Psychopathology
Psychopathology
Improving Mental Health Services for Economically Disadvantaged Children: Training Teachers
Children from low socioeconomic levels are more likely to have a mental disorder. However, they are less likely to receive appropriate treatment for that disorder than are children at higher socioeconomic levels.
- Trial name
- NCT00069563
- Testing
- Reaching Educators, Children, and Parents (RECAP)
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neurocognitive Impairment, Acute Lymphoblastic Leukemia
Risk of Psychopathology and Neurocognitive Impairment in Leukemia Survivors
1. This study will evaluate the association between changes in basic cognitive and behavioral functioning by the end of chemotherapy treatment, and the later development of higher order executive functions in pediatric acute…
- Trial name
- NCT01014195
- Testing
- Neurocognitive and behavioral evaluation
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- St. Jude Children's Research Hospital
Emotion Regulation
Neuroplastic Adaptations in Youth at High Risk for Developing Psychopathology
This pilot study aims to inform decision-making for a bigger study we intend to conduct in the future. The larger investigation will explore how helpful a treatment program for youth (ages 17 - 24) with emotion dysregulation (ED)…
- Trial name
- NCT05586425
- Testing
- Emotion Regulation Skills + Treatment as Usual, Treatment as Usual
- Volunteers
- 20 people
- Sponsor
- McMaster University
Adolescent, Psychopathology
An Evidence-based Family Support Program for Parents and Children in Palestine: A Theory-based Intervention
Few evidence-based programs exist to support children and families affected by sociopolitical conflict, despite documented evidence of their heightened risk for emotional and behavioral adjustment problems associated with…
- Conditions
- Adolescent, Psychopathology, Parent-Child Relations, Violence
- Trial name
- NCT05706376
- Testing
- Promoting Positive Family Futures, Treatment as Usual
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Bipolar Disorder, Involutional Depression
Study of the Psychological Development of Children of Parents With and Without Affective Disorders
This research study is the continuation of a study started more than 20 years ago. The study was designed to explore the effect that depressed parents have on their children and to better understand the factors that contribute to…
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001170
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Emotional Problem, Behavior Problem
Enhancement of Emotion Regulation Skills in Adolescents
For the current study, a prevention program is developed and applied to enhance the emotion regulation skills of adolescents. Before and after the application of the prevention program, all participants will be assessed for their…
- Trial name
- NCT04001140
- Testing
- Enhancement of emotion regulation skills
- Where
- Cyprus
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Antisocial Behavior, Psychopathology
Age-17 Follow-up of Home Visiting Intervention
This study is a longitudinal follow-up of 670 primarily African-American women and their 17-year-old firstborn children enrolled since 1990 in a highly significant randomized controlled trial (RCT) of prenatal and infancy home…
- Conditions
- Antisocial Behavior, Psychopathology, Substance Use, HIV Infections
- Trial name
- MemphisY17 (NCT00708695)
- Testing
- Nurse Home Visiting
- Where
- United States
- Volunteers
- 1,880 people
- Sponsor
- University of Colorado, Denver
Distress, Emotional, Internalizing Mental Health Symptoms
Piloting a School-Based Distress Tolerance Skills Program for Adolescents
Research suggests that an individual's perceived ability to withstand distressing or upsetting emotions (i.e., distress tolerance; DT) is a common risk factor across several mental health conditions that commonly emerge during…
- Trial name
- STRIDE (NCT06638853)
- Testing
- Distress Tolerance Skills Training
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chromosome 22q11.2 Deletion Syndrome
Genetics and Psychopathology in the 22q11 Deletion Syndrome
The purposes of this study are to: 1. study the nature and longitudinal course of psychiatric symptoms in children with the 22q11.2 deletion syndrome and 2. identify genes that contribute to the occurrence of these symptoms.
- Trial name
- NCT00161109
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Mental Illness, Schizophrenia
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Severe mental illness (SMI) refers to the most burdensome psychiatric conditions. The need to pre-empt the onset of SMI is pressing because once SMI develops, quality of life is poor and available treatments have limited…
- Conditions
- Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- IMAGINE (NCT03601026)
- Testing
- Genetic counselling
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Medical Education
Add-on Video-based Training on Mental Status Examination Skills
The goal of this clinical triall is to investigate the training effect of access to authentic patient video on mental status examination performance among 5th year Danish medical students.
- Trial name
- VV-RCT (NCT05795387)
- Testing
- Video-based self-regulated training on the mental status exam, E-course with written material on the mental status exam
- Where
- 2 sites in Denmark
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Personality Disorder
An Evolutionarily Informed Conceptualization of Personality Pathology
The purpose of this study is to explore the reliability of a new evolutionarily-informed model for conceptualizing personality pathology.
- Trial name
- EIC-PP (NCT06623838)
- Testing
- Evolutionarily informed case conceptualization
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tages Onlus
Psychopathology, Child Mental Health
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it…
- Conditions
- Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders
- Trial name
- NCT07641244
- Testing
- Psychological fMRI task
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Northwestern University
Rejection Sensitivity, Puberty
Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences.
- Conditions
- Rejection Sensitivity, Puberty, Psychopathology
- Trial name
- NCT06777823
- Testing
- Social Rejection Task
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Anxiety Symptoms, Depressive Symptoms
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
The goal of the project is to test whether a single-session intervention teaching incremental theories of personality, or the belief that one's personality is malleable, can strengthen recovery from social stress and reduce the…
- Trial name
- NCT03132298
- Testing
- Implicit Theories of Personality Program, Control Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Harvard University
FOXP1 Syndrome
Psychiatric Phenotype Characterization of Individuals With FOXP1 Syndrome
FOXP1 syndrome is a rare genetic disorder with a variable phenotype, characterized somatically by facial dysmorphia, dysphagia, hypotonia, relative or real macrocephaly, which may be associated with cerebral, cardiac, urogenital…
- Trial name
- FOXP1-PP (NCT06211673)
- Testing
- Semi-structured interviews, Heteroquestionnaires
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Developmental Psychological Disorder
Developmental Psychopathology and the Gene-environment Interaction
The present is a followup study that aims at investigating the effect of genetic and environmental factors on the possible development of psychopathological conditions in a longitudinal perspective.
- Trial name
- TwinAger (NCT04489069)
- Testing
- MRI, Clinical and Neuropsychological evaluations, Drawing DNA sample
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Intergenerational Relations
Maternal Psychopathology and Offspring Mental Health (PSI_PER)
Pregnant women consecutively referred to the Perinatal Psychiatric Outpatient Department, those in charge of the Psychiatric Outpatient Department and pregnant healthy controls from the general population will be recruited on a…
- Trial name
- PSI_PER (NCT03897816)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Bipolar Disorder
Interpersonal and Social Rhythm Therapy for Adolescents With Bipolar Disorder
This study will evaluate the effectiveness of interpersonal and social rhythm therapy in treating adolescents with a bipolar spectrum disorder
- Trial name
- NCT00576355
- Testing
- Interpersonal and Social Rhythm Therapy for Adolescents (IPSRT-A), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
Oppositional Defiant Disorder
Emotion Regulation as a Moderator of Two Different Treatments for Children With ODD
The goal of this randomized controlled trial is to is to test emotion regulation as a moderator of two different treatments for children with Oppositional Defiant Disorder (ODD).
- Trial name
- NCT06194994
- Testing
- Parent Management Training, Tuning Your Temper
- Where
- Iceland
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Iceland