Clinical trials: Pulmonary Function
ARDS, Human
Study of the Effects of Bronchoalveolar Lavage Liquid in the ARDS on the Functioning of the Neutrophil Polynuclear System
Firstly, the study assesses the effect of bronchoalveolar lavage fluid (BAL) from patients in (acute respiratory distress syndrome (ARDS) on the life span of PNNs and on the phagocytosis of apoptotic cells by macrophages and…
- Trial name
- BALARDS (NCT04008225)
- Testing
- Bronchoalveolar lavage
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Rennes University Hospital
Asthma
Effects of an Exercise Program for Children With Asthma
exercise program in the pulmonary function and cardiorespiratory fitness in children with asthma and respiratory symptoms
- Trial name
- NCT02693301
- Testing
- Exercise program
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- Universidad Europea de Madrid
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Asthma, Respiratory Sounds
Treatment of Persistent Wheezing in Infants and Children
Wheezing is a high-pitched whistling sound that is produced when air flows through narrowed lung airways. It is a common symptom of asthma.
- Trial name
- NCT00301171
- Testing
- Inhaled Fluticasone
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Duchenne Muscular Dystrophy
Relationship Between PFTs and Pdi in DMD
A cross-sectional study to explore the relationship between clinically assessed pulmonary function test (PFT) measures and transdiaphragmatic (Pdi) measures in Duchenne muscular dystrophy (DMD) as well as to explore the…
- Trial name
- NCT03335384
- Testing
- Esophageal Balloon, Gastric Balloon, Nasal Pressure Transducer
- Sponsor
- University of Minnesota
COPD
Continuous Versus High Intensity Interval Exercise in Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is characterized by exercise intolerance, which is a prognostic factor of disease severity and mortality and is usually attributed to ventilatory limitations.
- Trial name
- NCT07707271
- Testing
- Moderate intensity continuous aerobic exercise (MICE), High-intensity interval aerobic exercise (HIIE)
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- George Papanicolaou Hospital
Respiratory Insufficiency
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure
The purpose of this study is to compare two common methods of providing respiratory support: nasal continuous airway pressure and high flow nasal cannula to see what effect it has on babies breathing.
- Trial name
- NCT01531465
- Testing
- Pulmonary Function Testing & esophageal pressure monitoring, Pulmonary function testing and esophageal pressure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Neuromuscular Disease, Inspiratory Muscle Training
Manual Therapy and Inspiratory Muscle Training in Neuromuscular Disease
The benefits of inspiratory muscle training (IMT) have been reported in neuromuscular diseases. However, its effects are limited.
- Conditions
- Neuromuscular Disease, Inspiratory Muscle Training, Manual Therapy
- Trial name
- NCT07416929
- Testing
- inspiratory muscle training, Manual therapy, Conventional physiotherapy programme
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istinye University
Cystic Fibrosis
Time to Perform Lung Function Test in Cystic Fibrosis
Time to perform lung function test after chest physiotherapy in cystic fibrosis. The investigators study FEV1(forced expiratory volume in one second) and FVC (forced vital capacity).
- Trial name
- NCT01737801
- Testing
- Lung function test
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska University Hospital
Asthma, Vitamin D Deficiency
Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial
This is a pilot randomized controlled trial of lower vs. higher dose vitamin D supplementation in D-deficient asthmatic children, to determine necessary sample sizes for outcome measures in a larger multisite study, and to…
- Trial name
- D-Asthma (NCT02054975)
- Testing
- Vitamin D2 + vitamin D3, Vitamin D3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nationwide Children's Hospital
Obesity
The Impact of Bariatric Surgery Induced Weight Loss on Lung Function in Adolescents
In this prospective study we will evaluate the changes in respiratory physiology occurring in morbidly obese adolescents following bariatric surgery at Schneider Children's Medical Center of Israel (SCMCI).
- Trial name
- NCT02644174
- Testing
- Bariatric Surgery
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
COPD (Chronic Obstructive Pulmonary Disease)
Eecentric Exercise on Cardiopulmonary Fitness and Quality of Life With Chronic Obstructive Pulmonary Disease
This study aims to investigate the effects of elliptical exercise on the six-minute walk test and quality of life in patients with chronic obstructive pulmonary disease (COPD) to identify the most efficient exercise training…
- Trial name
- NCT06869720
- Testing
- Eccentric bike, conventional group
- Where
- Taiwan
- Sponsor
- Fu Jen Catholic University
Asthma, Asthma Attack
Evaluating Asthma Exacerbation-induced Changes in Lung Function With a Home-based Spirometer
The investigators will study the use of a home-based spirometer (Spirobank Smart spirometer) that connects to a smartphone app (VitalFlo) in teenagers with persistent asthma to determine if clinically significant changes in lung…
- Conditions
- Asthma, Asthma Attack, Asthma, Allergic
- Trial name
- NCT03705325
- Testing
- Spirobank Smart spirometer
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- VitalFlo Inc.
Asthma, Rhinitis
Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history…
- Trial name
- NCT00952835
- Testing
- regular treatment
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Universita di Verona
Cystic Fibrosis
Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).
- Trial name
- BEGIN (NCT04509050)
- Testing
- Ivacaftor or elexacaftor/tezacaftor/ivacaftor
- Where
- 35 sites in United States
- Volunteers
- 210 people
- Sponsor
- Sonya Heltshe
Cerebral Palsy
Effect of Intrathorathic Oscillations on Pulmonary Functions in Children With Cerebral Palsy
Aim: To investigate the effect of intrathoracic oscillations on forced expiratory volume at first second and peak expiratory flow in the children with cerebral palsy.
- Trial name
- NCT05252663
- Testing
- Quake device training, Traditional chest physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Pulmonary Hypertension
Effect of Nasal Highflow on Right Heart Function
In this study effect of NHF on pulmonary thermodynamic parameters will studied.
- Trial name
- HÄMOFLOW (NCT02885116)
- Testing
- Nasal high flow (NHF) supplementation, oxygen supplementation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Leipzig
Asthma
Effects of Inhaled Ciclesonide Versus Fluticasone Propionate Versus Placebo on Lower Leg Growth in Prepubertal Children With Mild Persistent Asthma (6 to 12 y) (BY9010/M1-208)
The aim of the study is to compare the effects of ciclesonide inhaled at one dose level twice daily versus fluticasone propionate inhaled at one dose level twice daily versus placebo, on short-term lower leg growth in prepubertal…
- Trial name
- NCT00163371
- Testing
- Ciclesonide
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- AstraZeneca
Asthma, Covid19
Impact of COVID19 on Asthma Patients in Spain
This research project aims to investigate the impact of COVID-19 on asthmatic patients, particularly focusing on whether the viral infection exacerbates asthma or affects control and lung function in the short to medium term.
- Trial name
- IMCAS (NCT05064501)
- Testing
- spirometry, Asthma control test
- Where
- 2 sites in Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Respiratory Distress Syndrome
Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome
The purpose of this study is to assess long term (1 year) respiratory sequelae in children surviving an acute respiratory distress syndrome
- Trial name
- NCT01435889
- Where
- 5 sites in Belgium, France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Lille