Clinical trials: Pulmonary Function
Cystic Fibrosis
Safety and Efficacy of an Antioxidant-rich Multivitamin Supplement in Cystic Fibrosis
The purpose of this study is to test the safety and efficacy of the final commercial formulation of an antioxidant enriched multivitamin supplement in softgel capsule form (AquADEKs) in increasing the plasma levels of certain…
- Trial name
- NCT01018303
- Testing
- AquADEK
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Cystic Fibrosis
Remotely Supervised Exercise for Adults With Cystic Fibrosis
Cystic fibrosis (CF) is a genetic disease characterized by abnormal chloride transport in epithelial tissues. Inflammation is a key component contributing to the main alterations induced by the disease.
- Trial name
- NCT05173194
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Europea de Madrid
COPD
Physical Function in Patients With Chronic Obstructive Pulmonary Disease
The aims of the study are to examine the responsiveness of, and the correlation between field walk tests and physical performance test in patients with chronic obstructive pulmonary disease (COPD) after participating in pulmonary…
- Trial name
- NCT04107831
- Testing
- Pulmonary rehabilitation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
Pneumonia
Reflex Rolling Versus Lung Squeezing Techniques On Pulmonary Functions In Premature Neonate With Pneumonia
Respiratory problems in neonates are one of the leading causes of neonatal morbidity and mortality in developing countries. These respiratory problems are seen in premature neonates, which mainly include respiratory distress…
- Trial name
- NCT06706128
- Testing
- reflex rolling technique, lung squeezing technique
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Delta University for Science and Technology
COPD, OSA
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient.
- Trial name
- NCT05254431
- Testing
- Exercise
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Asthma in Children
Effect of Osteopathic Manipulation Therapy on Pulmonary Function Testing in Children With Asthma
Objective To evaluate change in same-day pulmonary function testing in pediatric patients receiving OMT compared to those receiving usual care.
- Trial name
- NCT04764877
- Testing
- Osteopathic Manipulative Medicine
- Volunteers
- 58 people
- Sponsor
- Nationwide Children's Hospital
Lung Cancer, Thoracic Cancer
Exploring Robotic-assisted Thoracic Surgery for Lung Cancer
Background Surgery for lung cancer can be performed using open (thoracotomy) or minimally invasive techniques (Video Assisted Thoracic Surgery (VATS)).
- Conditions
- Lung Cancer, Thoracic Cancer, Surgery
- Trial name
- ROSE (NCT03658083)
- Testing
- Thoracotomy, Robotic-assisted thoracic surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Teesside University
COVID-19-Associated Encephalitis, Long COVID
Longterm Influence of Pediatric Long COVID Syndrome
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed.
- Trial name
- NCT05566392
- Testing
- Brain MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma
The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Asthma is a common inflammatory airway disease. Several researches have demonstrated a possible connection between asthma and exposure to paracetamol.
- Trial name
- NCT01073748
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Lung Function, BPD - Bronchopulmonary Dysplasia
Early-life MRI Biomarkers of Longer-term Respiratory Morbidity in Infants Born Extremely Preterm (EMBLEM)
Bronchopulmonary dysplasia (BPD) is a common, major complication of premature birth, associated with developmental and health consequences that continue into adulthood.
- Trial name
- EMBLEM (NCT06065215)
- Testing
- Magnetic Resonance Imaging (MRI), Echocardiogram, Lung ultrasound
- Where
- 4 sites in Canada
- Volunteers
- 319 people
- Sponsor
- Children's Hospital of Eastern Ontario
Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive
Growth, Health and Development in Children Born Extremely Preterm
Background: In a national Norwegian cohort of children born before 28 weeks gestation or with a birth weight less than 1000 g born in 1999 and 2000, 372 survived.
- Conditions
- Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive, Disorder of Bone Density and Structure, Unspecified, Cognition Disorders
- Trial name
- PEP11 (NCT01150071)
- Where
- 2 sites in Norway
- Volunteers
- 232 people
- Sponsor
- University of Bergen
Pulmonary Hypertension
Effect of Nasal Highflow on Right Heart Function
In this study effect of NHF on pulmonary thermodynamic parameters will studied.
- Trial name
- HÄMOFLOW (NCT02885116)
- Testing
- Nasal high flow (NHF) supplementation, oxygen supplementation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Leipzig
Mild Persistent Asthma
Response of FeNO, Small Airway Dysfunction and Lung Heterogeneity to 2-week Montelukast Treatment in Asthmatic Children.
This study aims to identify markers to prove rapid improvement of lung function, airway inflammation and bronchodilator response after 2-week LTRA administration.
- Trial name
- NCT01581710
- Volunteers
- 32 people
- Sponsor
- CHA University
Ventricular Dysfunction, Asthma in Children
Evaluation of Cardiac Biomarkers and Ventricular Function in Asthmatic Children
Evaluation of cardiac biomarkers and the left and right ventricular systolic and diastolic function in asthmatic children in Assuit university hospital
- Trial name
- NCT05985720
- Volunteers
- 50 people
- Sponsor
- Assiut University
Cystic Fibrosis
Self Drainage in Pediatric Cystic Fibrosis Patients
In the current study, we designed a cross-over, open label, randomized controlled clinical trial that aim to investigate the superiority of physical exercise coupled with self drainage to a chest physiotherapy in stable cystic…
- Trial name
- GYM-MUCO (NCT01509235)
- Testing
- Chest physiotherapy
- Volunteers
- 34 people
- Sponsor
- Hospices Civils de Lyon
Mild Asthma
PAXT: Pulmonary Imaging of Mild Asthma Using 129Xe MRI and Tc-99-Labeled-Carbon-Imaging (Tc99CImaging)
The goal of this observational study is to better understand how asthma affects the lungs in young adults (ages 17-35) with mild asthma.
- Trial name
- PAXT (NCT07143747)
- Testing
- Hyperpolarized 129Xe MRI, Tc-99m Technegas Ventilation Imaging
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Grace Parraga
Asthma (Diagnosis)
Respiratory Admittance by Oscillometry in Children
Oscillometry is a pulmonary function testing technique suited for children because it does not require specific respiratory maneuvers like spirometry.
- Trial name
- ArsEIB (NCT07771608)
- Volunteers
- 144 people
- Sponsor
- Central Hospital, Nancy, France
Growth Hormone Deficiency
Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD)
The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of…
- Trial name
- GHD (NCT02507245)
- Testing
- Growth Hormone-Releasing Hormone
- Volunteers
- 48 people
- Sponsor
- Stefania La Grutta, MD
Early Onset Scoliosis, Congenital Spinal Deformities
The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study
The purpose of this study is to examine the treatment, both surgical and non-surgical, of patients with any form of early onset scoliosis.
- Conditions
- Early Onset Scoliosis, Congenital Spinal Deformities, Infantile Idiopathic Scoliosis, Neuromuscular Spinal Deformity
- Trial name
- GSSG (NCT02299362)
- Where
- 27 sites in United States, Canada and 5 more
- Volunteers
- 2,602 people
- Sponsor
- Growing Spine Study Group
Cystic Fibrosis, Exercise
Effects of Telerehabilitation-based Exercises in Cystic Fibrosis
Pulmonary rehabilitation programs are an important part of lifelong therapy in the treatment of patients with cystic fibrosis. Although the possible benefits of exercise are known, physical activity levels and participation in…
- Conditions
- Cystic Fibrosis, Exercise, Telerehabilitation, Exercise Capacity
- Trial name
- NCT05590169
- Testing
- Exercise training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University