Clinical trials: Pulpitis - Reversible
Reversible Pulpitis
Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars
The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate as medicament agent
- Trial name
- NCT04374214
- Testing
- Complete Pulpotomy using Mineral Trioxide Aggregate, Complete Pulpotomy using Simvastain -alphatricalcium phosphate
- Where
- India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Irreversible Pulpitis, Reversible Pulpitis
In Vivo Pulp Thermal Changes During Different Slenderization Techniques
The goal of this study is to learn about the temperature rise inside the living part of a tooth (the pulp) during different ways of removing a small amount of enamel (the hard outer layer of the tooth), a procedure called…
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Thermal Injury, Pulp Hyperemia
- Trial name
- IPR (NCT07391124)
- Testing
- High-Speed Air-Driven Drill (Airotor and Bur), Orthodontic IPR Kit (Oscillating System)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Reversible Pulpitis
Direct Pulp Capping Agent on Human Pulp Tissue
This in- vivo study was conducted to evaluate the response of human pulp tissue following direct pulp capping using four different pulp capping agents in premolars scheduled for extraction in patients undergoing orthodontic…
- Trial name
- NCT06435065
- Testing
- Biodentine, Mineral Tri-Oxide Aggregate, THERACAL LC
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DR SURINDER SACHDEVA
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Pulpitis - Reversible, Pulpotomies on Primary Molars
Pelargonium Graveolens Essential Oil as a Pulpotomy Agent in Primary Teeth
The success of pulpotomy in primary teeth is critical for preserving function and arch integrity in children and depends largely on the biological properties of the medicament used.
- Trial name
- NCT07386925
- Testing
- pulpotomy, Radiation
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Pulpitis Reversible, Pulp Exposure, Dental
Pomegranate Peel Extract for Primary Molar Pulpotomy
Pomegranate peel extract has demonstrated a range of potential uses in the biomedical industry in recent years because of its numerous benefits, which include anti-inflammatory, antibacterial, anti-apoptotic, antioxidant, and…
- Trial name
- NCT07108738
- Testing
- Pulpotomy, Radiation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Reversible Pulpitis
Assessment of a New Protocol for Indirect Pulp Capping Procedures
The aim of the study is to assess clinically, radiographically and microbiologically a new protocol for indirect pulp capping procedures compared to the conventional protocol in painful teeth.
- Trial name
- NCT03071588
- Testing
- Mechanical rotary burs, Carisolv gel
- Volunteers
- 86 people
- Sponsor
- King's College London
Deep Caries, Reversible Pulpitis
Similar Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine™
This study aimed to evaluate the clinical performance of White MTA (MTA, Angelus, Londrina, Brazil) and Biodentine™ in pulp capping of cariously exposed mature permanent teeth.
- Conditions
- Deep Caries, Reversible Pulpitis, Irreversible Pulpitis
- Trial name
- NCT03186690
- Testing
- Biodentine, Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Reversible Pulpitis, Irreversible Pulpitis
Cytokines as Diagnostic Markers of Pulpal Inflammation and Their Impact on the Outcome of Vital Pulp Therapy
intervention eligible patients with teeth diagnosed with reversible or irreversible pulpits will go for vital pulp therapy and the other group will be patients will go for extraction of caries free teeth for orthodontic reasons…
- Trial name
- Pulp Therapy (NCT07261761)
- Testing
- Vital pulp therapy, Extraction, blood sample collection
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Pulpitis - Irreversible, Pulpitis - Reversible
Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Presepsin Levels in the Pulpal Blood.
Observational cross-sectional study aims to determine the correlation between pulpal status and IL-8 and Presepsin levels in the pulpal blood.
- Trial name
- Cross-section (NCT07466095)
- Testing
- IL-8 and Presepsin levels in the pulpal blood.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Reversible Pulpitis
Survival Rate After TheraCal PT Pulpotomy Versus MTA Pulpotomy in Children With Vital Primary Molars.
The aim of the study is to assess the effect of TheraCal PT pulpotomy versus MTA pulpotomy on the survival rate of cariously exposed vital primary molars.
- Trial name
- NCT04617600
- Testing
- MTA, TheraCal PT
- Volunteers
- 20 people
- Sponsor
- Cairo University
Reversible Pulpitis, Caries
Electrical and Formocresol Pulpotomy in Primary Molars
1. The investigator hypothesize that the Laser pulpotomy will provide adequate and comparable success clinically in primary molars. 2.
- Trial name
- NCT01622153
- Testing
- Formocresol application after pulpotomy preparation, GENTLEray 980 Soft Tissue diode laser
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University Hospitals Cleveland Medical Center
Reversible Pulpitis, Dental Pulp Diseases
Success and Color Stability of MTA Pulpotomized Primary Molars: an RCT
Mineral trioxide aggregate has been previously FDA approved as an endodontic filler. Its use in vital teeth has demonstrated significant color change post-treatment leaving it ineffective for esthetic use..
- Trial name
- MTA (NCT02702505)
- Testing
- NeoMTA, ProRoot MTA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas A & M University Baylor College Of Dentistry
Reversible Pulpitis
Effect of Liners on Pulpal Outcome and Restoration Survival After Partial Caries Excavation
Aim of the study was to determine the effectiveness of cavity liners regarding survival of restoration beneath composite restoration after partial caries removal in permanent teeth with deep caries and to evaluate and compare the…
- Trial name
- NCT03286959
- Testing
- PCR with calcium hydroxide, PCR with RMGIC, PCR with direct composite
- Volunteers
- 198 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Reversible Pulpitis
TheraCal PT vs. Formocresol in Primary Molar Pulpotomies
This prospective, randomized, parallel-group clinical trial evaluated the 12-month clinical and radiographic success rates of TheraCal PT versus formocresol in primary molar vital pulpotomies among 50 children aged 5 to 8 years.
- Trial name
- NCT07864181
- Testing
- Dual cured resin modified
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Hama University
Reversible Pulpitis, Irreversible Pulpitis
Evaluation of Pulpal Biomarkers in Vital Pulp Therapy
This prospective clinical study aims to evaluate the association between the levels of selected pulpal biomarkers and the clinical success of vital pulp therapy in permanent teeth.
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Vital Pulp Therapy, Dental Pulp Diseases
- Trial name
- NCT07073573
- Testing
- Vital pulp therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- ertuğrul karataş
Deep Caries, Indirect Pulp Capping
Pulp Capping in Primary Molars Using TheraCal (LC)
A randomized clinical trial that aims to evaluate clinical and radiographic success rates of indirect pulp capping and direct pulp capping in primary molars with reversible pulpitis using a light-cured tri-calcium silicate base…
- Conditions
- Deep Caries, Indirect Pulp Capping, Direct Pulp Capping, Reversible Pulpitis
- Trial name
- NCT05167123
- Testing
- Light cured tri-calcium silicate base material
- Where
- 3 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Reversible Pulpitis
The Role of Matrix Metalloproteinases on the Primary Teeth Pulpotomy Treatments
Matrix metalloproteinases (MMPs) are important zinc enzyme group that responsible for reducing extracellular matrix components. It has been reported that MMPs play an important role in pulpal inflammation.
- Trial name
- NCT05145686
- Testing
- Matris metalloproteinase -2, -8, -9 expressions
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ege University
Reversible Pulpitis, Irreversible Pulpitis
Biomarkers for Differentiating Reversible and Irreversible Pulpitis
This observational study aims to evaluate the role of inflammatory, oxidative stress, neurogenic, and immunological biomarkers obtained from pulpal blood in the differential diagnosis of normal pulp, reversible pulpitis, and…
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Healthy Pulp
- Trial name
- PULPBIOM (NCT07658742)
- Testing
- Pulpal Blood Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Safa