Clinical trials: Pulpitis - Reversible
Reversible Pulpitis
Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars
The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate as medicament agent
- Trial name
- NCT04374214
- Testing
- Complete Pulpotomy using Mineral Trioxide Aggregate, Complete Pulpotomy using Simvastain -alphatricalcium phosphate
- Where
- India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Irreversible Pulpitis, Reversible Pulpitis
In Vivo Pulp Thermal Changes During Different Slenderization Techniques
The goal of this study is to learn about the temperature rise inside the living part of a tooth (the pulp) during different ways of removing a small amount of enamel (the hard outer layer of the tooth), a procedure called…
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Thermal Injury, Pulp Hyperemia
- Trial name
- IPR (NCT07391124)
- Testing
- High-Speed Air-Driven Drill (Airotor and Bur), Orthodontic IPR Kit (Oscillating System)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Reversible Pulpitis
Direct Pulp Capping Agent on Human Pulp Tissue
This in- vivo study was conducted to evaluate the response of human pulp tissue following direct pulp capping using four different pulp capping agents in premolars scheduled for extraction in patients undergoing orthodontic…
- Trial name
- NCT06435065
- Testing
- Biodentine, Mineral Tri-Oxide Aggregate, THERACAL LC
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DR SURINDER SACHDEVA
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Deep Caries, Pulpitis Reversible
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults.
- Conditions
- Deep Caries, Pulpitis Reversible, Pulp Hyperemia
- Trial name
- NCT05816525
- Testing
- Partial removal of carious tissue, Final restoration
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Pulpitis - Reversible, Pulpotomies on Primary Molars
Pelargonium Graveolens Essential Oil as a Pulpotomy Agent in Primary Teeth
The success of pulpotomy in primary teeth is critical for preserving function and arch integrity in children and depends largely on the biological properties of the medicament used.
- Trial name
- NCT07386925
- Testing
- pulpotomy, Radiation
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Deep Carious Lesions, Reversible Pulpitis
Indirect Pulp Capping With Biodentine and TheraCal LC in Permanent Mature Molars
Management of deep carious lesions in permanent mature molars with reversible pulpitis represents a challenge for clinicians. Vital pulp therapy includes indirect and direct pulp capping, partial pulpotomy and full pulpotomy.
- Conditions
- Deep Carious Lesions, Reversible Pulpitis, Indirect Pulp Capping
- Trial name
- NCT03741816
- Testing
- Indirect pulp capping
- Where
- Spain
- Volunteers
- 212 people
- Sponsor
- University of Valencia
Carious Exposure, Human Permanent First and Second Molars
RCT of Pulp Capping Over Carious Exposure in Adults
This multicentre study was a randomized, controlled, parallel, patient-blinded, two-arm superiority trial with a 1:1 allocation ratio that followed the CONSORT guidelines.The aim of this study was to investigate whether MTA is…
- Conditions
- Carious Exposure, Human Permanent First and Second Molars, Mature Teeth, Proximal Caries
- Trial name
- NCT01224925
- Testing
- Direct pulp capping with Dycal, Direct pulp capping
- Where
- 4 sites in Lithuania, Norway
- Volunteers
- 80 people
- Sponsor
- University of Tromso
Pulpitis Reversible, Pulp Exposure, Dental
Pomegranate Peel Extract for Primary Molar Pulpotomy
Pomegranate peel extract has demonstrated a range of potential uses in the biomedical industry in recent years because of its numerous benefits, which include anti-inflammatory, antibacterial, anti-apoptotic, antioxidant, and…
- Trial name
- NCT07108738
- Testing
- Pulpotomy, Radiation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Reversible Pulpitis
Assessment of a New Protocol for Indirect Pulp Capping Procedures
The aim of the study is to assess clinically, radiographically and microbiologically a new protocol for indirect pulp capping procedures compared to the conventional protocol in painful teeth.
- Trial name
- NCT03071588
- Testing
- Mechanical rotary burs, Carisolv gel
- Volunteers
- 86 people
- Sponsor
- King's College London
Deep Caries
Deep Caries in Mature Teeth With Reversible Pulpitis
This clinical trial will be conducted to clinical, radiographical and histological evaluation of pulp condition with reversible pulpities after total and selective removal of primary and secondary caries (randomized clinical…
- Trial name
- NCT07028905
- Testing
- Total caries removal, Partial caries removal
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Minia University
Deep Caries, Reversible Pulpitis
Similar Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine™
This study aimed to evaluate the clinical performance of White MTA (MTA, Angelus, Londrina, Brazil) and Biodentine™ in pulp capping of cariously exposed mature permanent teeth.
- Conditions
- Deep Caries, Reversible Pulpitis, Irreversible Pulpitis
- Trial name
- NCT03186690
- Testing
- Biodentine, Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Reversible Pulpitis
Role Of Wound Lavage in Direct Pulp Capping Of Permanent Teeth With Carious Exposure
the purpose of the study is to investigate the outcome of wound lavage agents Sodium hypochlorite and Ethylenediaminetetraacetic acid (EDTA) in direct pulp capping of mature permanent teeth with carious exposure.
- Trial name
- NCT05878249
- Testing
- wound lavage with normal saline, wound lavage with sodium hypochlorite, wound lavage with Ethylenediaminetetraacetic acid(EDTA)
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Reversible Pulpitis, Irreversible Pulpitis
Cytokines as Diagnostic Markers of Pulpal Inflammation and Their Impact on the Outcome of Vital Pulp Therapy
intervention eligible patients with teeth diagnosed with reversible or irreversible pulpits will go for vital pulp therapy and the other group will be patients will go for extraction of caries free teeth for orthodontic reasons…
- Trial name
- Pulp Therapy (NCT07261761)
- Testing
- Vital pulp therapy, Extraction, blood sample collection
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Irreversible Pulpitis, Reversible Pulpitis
Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy
The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy.
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Dentine Caries
- Trial name
- Vitapulp (NCT04807244)
- Testing
- Selective Caries Removal with Biodentine™, Partial Pulpotomy with Biodentine™, Full Pulpotomy with Biodentine™
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pulpitis - Irreversible, Pulpitis - Reversible
Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Presepsin Levels in the Pulpal Blood.
Observational cross-sectional study aims to determine the correlation between pulpal status and IL-8 and Presepsin levels in the pulpal blood.
- Trial name
- Cross-section (NCT07466095)
- Testing
- IL-8 and Presepsin levels in the pulpal blood.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Reversible Pulpitis
Survival Rate After TheraCal PT Pulpotomy Versus MTA Pulpotomy in Children With Vital Primary Molars.
The aim of the study is to assess the effect of TheraCal PT pulpotomy versus MTA pulpotomy on the survival rate of cariously exposed vital primary molars.
- Trial name
- NCT04617600
- Testing
- MTA, TheraCal PT
- Volunteers
- 20 people
- Sponsor
- Cairo University
Reversible Pulpitis, Caries
Electrical and Formocresol Pulpotomy in Primary Molars
1. The investigator hypothesize that the Laser pulpotomy will provide adequate and comparable success clinically in primary molars. 2.
- Trial name
- NCT01622153
- Testing
- Formocresol application after pulpotomy preparation, GENTLEray 980 Soft Tissue diode laser
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University Hospitals Cleveland Medical Center
Reversible Pulpitis, Dental Pulp Diseases
Success and Color Stability of MTA Pulpotomized Primary Molars: an RCT
Mineral trioxide aggregate has been previously FDA approved as an endodontic filler. Its use in vital teeth has demonstrated significant color change post-treatment leaving it ineffective for esthetic use..
- Trial name
- MTA (NCT02702505)
- Testing
- NeoMTA, ProRoot MTA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas A & M University Baylor College Of Dentistry