Clinical trials: Purging
Acute Myelogenous Leukemia, Myelodysplastic Syndrome
Study of Gelonin Purging of Autologous Stem Cells for Transplantation
Patients with Acute Myelogenous Leukemia or Myelodysplastic are able to achieve a complete remission but fail to achieve a prolonged disease-free survival.
- Trial name
- NCT00043810
- Testing
- Gelonin, Busulfan, Fludarabine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Anorexia in Adolescence, Anorexia Nervosa
3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study
People with anorexia nervosa often become medically unstable because of severe malnutrition and require hospitalization for nutritional rehabilitation.
- Conditions
- Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- 3D-ED (NCT07726524)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Bulimia Nervosa, Eating Disorder
Rapid Response to Day Hospital Treatment in Bulimia Nervosa and Purging Disorder
Treatments for bulimia nervosa (BN) have relatively high rates of nonremission and relapse, meaning that improving treatments is a high priority in this area.
- Trial name
- CBT-RR (NCT02444065)
- Testing
- Cognitive Behavior Therapy (CBT), Motivational Interviewing (MI)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Binge Eating, Purging (Eating Disorders)
Emotion Regulation in Binge Eating and Purging Among Adolescents
The study will examine the neural and behavioral correlates of emotion regulation in adolescents engaging in binge eating and/or purging and healthy adolescents.
- Trial name
- NCT03429114
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden
Eating Disorders, Binge Eating
Naltrexone Neuroimaging
The purpose of this open-label, pilot study is to evaluate fMRI as a biomarker of opioid antagonism in adolescents with ED. Modulation of brain activation will be examined in regions of interest by fMRI using a food-specific and…
- Conditions
- Eating Disorders, Binge Eating, Purging (Eating Disorders)
- Trial name
- EDIT-N2 (NCT04935931)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Mercy Hospital Kansas City
Lymphoma, Non-Hodgkin
Enrichment & Purging of Stem Cells in Non-Hodgkin's Lymphoma
To evaluate the role of purging the hematopoietic cell graft on outcomes for non-Hodgkin's Lymphoma.
- Trial name
- NCT00186355
- Testing
- high dose chemo then auto hematopoietic cell transplant
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Stanford University
Eating Disorders, Binge Eating
Naltrexone Neuroimaging in Teens With Eating Disorders
Using a randomized, placebo-controlled, crossover study, this study will evaluate functional magnetic resonance imaging (fMRI) as a pharmacodynamic biomarker of opioid antagonism in adolescents with eating disorders.
- Conditions
- Eating Disorders, Binge Eating, Purging (Eating Disorders), Bulimia Nervosa
- Trial name
- NN-RCT (NCT05509257)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Mercy Hospital Kansas City
Bulimia Nervosa
Family Therapy for Adolescent Bulimia Nervosa
The primary hypotheses are: A procedurally distinct family therapy is an effective and essential way to reduce bingeing and purging in adolescents with BN, and leads to the long-term amelioration of bulimic symptoms.
- Trial name
- NCT00518843
- Testing
- FBT-BN, SPT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Chronic Myeloid Leukemia, Healthy
The Collection of Peripheral Blood Lymphocytes and Marrow Progenitor Cells From Normal Volunteers and Volunteers With Lymphoid or Hematologic Malignancies
Allogeneic bone marrow transplantation (BMT) is a curative treatment for patients with chronic myelogenous leukemia (CML) and other lymphoid/hematologic malignancies but is available as a treatment option to only a minority of…
- Conditions
- Chronic Myeloid Leukemia, Healthy, Hematologic Neoplasm, Lymphoma
- Trial name
- NCT00001432
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Neuroblastoma, Central Nervous System Tumors
Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas
Studies have provided evidence that residual microscopic malignant cells in autologous bone marrow or blood stem cell grafts can contribute to posttransplant relapse.
- Conditions
- Neuroblastoma, Central Nervous System Tumors, Lymphomas, Wilms Tumor
- Trial name
- NCT00152126
- Testing
- Stem Cell Transplantation, Busulfan, Melphalan
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- St. Jude Children's Research Hospital
Lymphoma
Cyclophosphamide W/or W/Out Rituximab and Peripheral Stem Cell Transplantation in Patients With Recurrent Non-Hodgkin's Lymphoma
RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- NCT00028665
- Testing
- filgrastim, rituximab, carmustine
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center
Type 1 Diabetes, Eating Disorders
Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes
The goal of this clinical trial is to test whether a new intervention works to treat eating disorders in type 1 diabetes. Participants are assigned to one of the following: (1) Acceptance and Commitment Therapy (ACT), (2)…
- Conditions
- Type 1 Diabetes, Eating Disorders, Disordered Eating Behaviors, Purging (Eating Disorders)
- Trial name
- NCT05540704
- Testing
- ACT, Supportive Diabetes Counseling
- Where
- 2 sites in United States
- Volunteers
- 235 people
- Sponsor
- Duke University