Clinical trials: Randomised Controlled Trial
Health Behavior
Healthy Parent Carers Feasibility Study
This study is a feasibility study of a peer-led group-based health promotion intervention for parent carers. It will used a parallel group randomised controlled trial design to compare a group based intervention called Healthy…
- Trial name
- NCT03705221
- Testing
- Healthy Parent Carers group programme, Healthy Parent Carers online resources
- Where
- 6 sites in United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Virtual Reality, Vaccination
Virtual Reality for the Treatment of Pain in Pediatric Vaccination
Objective: to estimate the effect of virtual reality as a distracting technique against traditional distracting techniques in the vaccination procedure in the pediatric population. Design: randomized clinical trial.
- Conditions
- Virtual Reality, Vaccination, Pain, Nursing
- Trial name
- NCT04096833
- Testing
- Virtual Reality Group
- Where
- Spain
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Alcohol Misuse, Drug Misuse
Family and Social Intervention for Young People
Research evidence shows that there is a high prevalence of substance use among young people in the UK. Early onset and high levels of use are associated with a range of negative outcomes, including increased risk of later…
- Trial name
- YSBNT (NCT02399865)
- Testing
- Youth Social Behaviour and Network Therapy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Tobacco Use
Address Tobacco Use Among Adolescents in Hong Kong
This study will examine the effectiveness of a social norms campaign in correcting smoking misperceptions, reducing smoking susceptibility and changing smoking-related behaviours in Hong Kong adolescents.
- Trial name
- NCT03264144
- Testing
- Social norms campaign
- Where
- Hong Kong
- Volunteers
- 12,868 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Neonatal Jaundice, Hyperbilirubinemia
Implementation of a Transcutaneous Bilirubinometer
Neonatal jaundice, caused by hyperbilirubinemia, is frequently seen in healthy newborns. Assessment of the degree of jaundice is usually done visually,and if necessary serum bilirubin is investigated in a blood sample.
- Trial name
- NCT01622699
- Testing
- Transcutaneous Bilirubinometer, visual assessment of neonatal jaundice
- Where
- Netherlands
- Volunteers
- 430 people
- Sponsor
- Princess Amalia Children's Clinic
Cystic Fibrosis
ActivOnline: Physical Activity in Cystic Fibrosis Trial UK
Increased level of physical activity (PA) are of benefit in the management of cystic fibrosis (CF). This randomised control tial will assess whether three-months use of an online platform can help increase PA levels in people…
- Trial name
- ActiOnPACTUK (NCT04249999)
- Testing
- ActivOnline
- Where
- United Kingdom
- Sponsor
- University of Exeter
Infant, Premature, Diseases, Airway Morbidity
Optimising Ventilation in Preterms With Closed-loop Oxygen Control
Many premature infants require respiratory support in the newborn period. Mechanical ventilation although life-saving is linked to complications for the lungs and other organs and its duration should be kept to a minimum.
- Conditions
- Infant, Premature, Diseases, Airway Morbidity, Mechanical Ventilation Complication
- Trial name
- NCT05030337
- Testing
- Closed-loop automated oxygen control (Oxygenie, SLE 6000)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- King's College Hospital NHS Trust
Back Pain, Low Back Pain
Neck and Low Back Pain in Physical Therapy Students at The University of the West Indies, Mona, Jamaica
The purpose of this study is to determine the prevalence of neck and low back pain among physical therapy students enrolled at The University of the West Indies, Mona.
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Spine Health
- Trial name
- NCT07177001
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Insomnia, Autism Spectrum Disorder (ASD)
Sleep Intervention in Children With ASD
The goal of this randomised controlled trial is to examine the following research questions: 1) whether digitally delivered parent-based behavioural sleep intervention with or without personalised support is effective in…
- Trial name
- NCT07398183
- Testing
- App-based CBT-I with personalised telephone support, App-based CBT-I without personalised telephone support
- Where
- Hong Kong
- Volunteers
- 195 people
- Sponsor
- The University of Hong Kong
Genetic Disorder, Noonan Syndrome
Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome
This trial is conducted in Asia. The aim of the trial is to investigate the long-term efficacy and safety of two doses of NN-220 (somatropin) in short stature due to Noonan syndrome.
- Trial name
- NCT01927861
- Testing
- somatropin
- Where
- 27 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Novo Nordisk A/S
Idiopathic Scoliosis
Trial on Three Treatments for Scoliosis
Idiopathic scoliosis is a three-dimensional structural deformity of the spine that occurs in children. Recent reviews on bracing and exercise treatment have provided some evidence for effect of these interventions.
- Trial name
- CONTRAIS (NCT01761305)
- Testing
- Hypercorrective night-time brace, Scoliosis specific exercises., Self-mediated physical activity.
- Where
- 7 sites in Sweden
- Volunteers
- 135 people
- Sponsor
- Karolinska Institutet
Chronic Pelvic Pain
Treatment of Ilioinguinal Entrapment Syndrome - an Often Overlooked Cause of Chronic Pelvic Pain
Neuralgic pain caused by entrapment of peripheral nerves is an often overlooked cause of chronic pelvic pain. The objective of the present study was to assess pain and quality of life in women with pain caused by entrapment of…
- Trial name
- NCT01020162
- Testing
- Amitryptiline, gabapentin, Resection of the ilioinguinal nerve
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Göteborg University
Taking a Throat Swab
The Effect of Animated Videos and Therapeutic Play Methods on Emotional Expression, Fear and Anxiety in Children Aged 4-8 Years During the Throat Swab Procedure
We planned a study to determine the effect of showing an animated video and using educational therapeutic play methods prior to throat swab procedures in children aged 4-8 years on the children's compliance with the procedure, as…
- Trial name
- NCT07693842
- Testing
- Animation video, Therapeutic Play
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Mersin University
Healthy
Acute Effects of Breakfast Compared With No Breakfast on Cognitive Function and Subjective State in 11-13 Year Old Children
This study is a school-based, randomised, controlled, parallel groups trial to examine the acute effect of breakfast (ready-to-eat-cereal and milk) vs.
- Trial name
- NCT03979027
- Testing
- Breakfast: ready-to-eat-cereal and milk
- Where
- United Kingdom
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Acute Respiratory Tract Infections, Diarrhea
Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT
Melghat is poorly developed tribal area in India with very high child mortality \& malnutrition prevalence (grossly inadequate medical facilities). Important health problems.
- Conditions
- Acute Respiratory Tract Infections, Diarrhea, Malaria, Neonatal Sepsis
- Trial name
- HBCC (NCT02473796)
- Testing
- Home based child care
- Where
- India
- Volunteers
- 7,594 people
- Sponsor
- MAHAN Trust
Malaria, Falciparum
Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.
This study seeks to establish whether intermittent preventive treatment (IPT) can reduce malaria among school-going children and its consequent impact on school performance.
- Trial name
- NCT00142246
- Testing
- Intermittent preventive treatment (SP and amodiaquine)
- Where
- Kenya
- Volunteers
- 6,758 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Ultrasound Training
Ultrasound Simulation or Traditional Ultrasound Training for General Practitioners?
The goal of this study is to compare two different educational methods for training general practitioners (GPs) in point-of-care ultrasound.
- Trial name
- NCT07127588
- Testing
- Simulation based clinical ultrasound education, Traditional ultrasound education
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain
Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of operations.
- Trial name
- NCT01848119
- Testing
- Gabapentin, lactose
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Childhood Apraxia of Speech
Methylphenidate in Childhood Apraxia of Speech
The purpose of this study is to describe the possible effects of methylphenidate (MPH) on speech intelligibility in children with childhood apraxia of speech (CAS) aged 6-12 years.
- Trial name
- NCT05185583
- Testing
- Methylphenidate Hydrochloride
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- Murdoch Childrens Research Institute
Regional Anesthesia Morbidity, Gallbladder Stone
LaGRA Trial in Laparoscopic Cholecystectomy
This study investigated the effectiveness of a surgeon administered, laparoscopic guided, regional anaesthesia technique.
- Conditions
- Regional Anesthesia Morbidity, Gallbladder Stone, Pain
- Trial name
- LaGRA (NCT03394807)
- Testing
- Levobupivacaine
- Volunteers
- 76 people
- Sponsor
- Health Service Executive, Ireland
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