Clinical trials: Randomised Controlled Trial
Attention-deficit/Hyperactivity Disorder, Special Education
Multiple Family Narrative Therapy for Chinese Families of Children With Attention Deficit Hyperactivity Disorder
The goal of this randomized controlled trial is to develop and to implement a multiple family narrative therapy intervention consisting of parent-child relationships training among Chinese families of children with attention…
- Conditions
- Attention-deficit/Hyperactivity Disorder, Special Education, Special Needs Children, Attention Deficit Disorder
- Trial name
- MFNT-CADHD (NCT06064942)
- Testing
- Multiple Family Narrative Therapy (MFNT), School services for families of children with ADHD
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- Hong Kong Baptist University
Alcohol Use Disorder
Effect of Hypnotherapy in Alcohol Use Disorder Compared to Motivational Interviewing.
This study was carried out at an inpatient clinic in Norway. A six- week long treatment programme included intensive group therapy, but also five hours of individual therapy, given as motivational interviewing (MI).
- Trial name
- NCT03583788
- Testing
- Hypnotherapy, Motivational Interviewing
- Volunteers
- 31 people
- Sponsor
- Sykehuset Innlandet HF
Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Anxiety, Anxiety Disorders
A Single-session Growth Mindset Intervention for Children and Young People With Mental Health Difficulties
The present study aims to evaluate whether an online, self-administered, single session intervention (SSI) increases children and adolescents' perceptions of control over external threats and their emotional experience and…
- Conditions
- Anxiety, Anxiety Disorders, Depression, Low Mood
- Trial name
- NCT04652362
- Testing
- Growth Mindset Online Single-Session Intervention, Supportive Therapy Online Single-Session Intervention (Control)
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Cytomegalovirus (CMV) Infection
ValgaNciclovIR for CMV Viraemia in AdvaNced HIV diseAse
The goal of this clinical trial is to learn if valganciclovir works to treat cytomegalovirus (CMV) infection in people with advanced HIV disease.
- Trial name
- NIRVANA (NCT07379203)
- Testing
- Valganciclovir
- Volunteers
- 130 people
- Sponsor
- Wits Health Consortium (Pty) Ltd
Encephalitis
Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis
This is a phase III multi-centre randomised, double blind, placebo controlled trial to assess the role of intravenous immunoglobulin in the treatment of children with encephalitis.
- Trial name
- IgNiTE (NCT02308982)
- Testing
- Immunoglobulins, Intravenous (Privigen)
- Where
- 25 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Oxford
Pediculosis Capitis, Head Louse Infestation
Cocamide DEA vs Permethrin for Head Lice
To assess the efficacy and safety of 10% Cocamide DEA and Lyclear creme rinse (permethrin1%) in the eradication of head lice. To assess the ability of each product to kill all viable ova and to assess patient acceptability of the…
- Trial name
- NCT02500524
- Testing
- Cocamide diethanolamine, Permethrin
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical Entomology Centre
Oral Health
Interactive Video- and Game-Based Oral Health Education for 11-Year-Old Schoolchildren
The goal of this cluster randomised controlled trial is to learn if an interactive video- and game-based oral health education intervention helps improve oral health outcomes among 11-year-old schoolchildren in Pulau Pinang…
- Trial name
- NCT07097324
- Testing
- Video- and Game-Based Oral Health Education, Conventional Oral Health Talk
- Where
- Malaysia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Advance Care Planning, Nursing Homes
Effect of Advance Care Planning to Improve Patient-centered Care of Nursing Home Residents
Advance Care Planning (ACP) is an approach to support individuals in understanding and sharing their values, treatment goals, and preferences regarding future medical care.
- Trial name
- BEVOR (NCT04333303)
- Testing
- Implementation of a complex regional Advance Care Planning program
- Where
- 4 sites in Germany
- Volunteers
- 5,927 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Atopic Dermatitis
Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).
Primary objective: To evaluate the efficacy of subcutaneous (SC) administration of tralokinumab compared with placebo in treating adolescent subjects (age 12 to <18 years) with moderate-to-severe AD.
- Trial name
- NCT03526861
- Testing
- Tralokinumab
- Where
- 87 sites in United States, Australia and 8 more
- Volunteers
- 301 people
- Sponsor
- LEO Pharma
Sickle Cell Disease
Vitamin D Supplementation in Children With Sickle Cell Disease
Sickle cell disease (SCD) is a genetic disease characterized by abnormal hemoglobin, the main constituent of red blood cells. People with SCD have nutritional deficiencies, and vitamin D deficiency is one of the most common.
- Trial name
- NCT03417947
- Testing
- Vitamin D bolus
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- St. Justine's Hospital
Postpartum, Fatigue
Postnatal Companion Support The Effect of Education on Maternal Depression and Fatigue
In this study, it is aimed to investigate the effect of the trainings included in the content of the practical guide for postpartum supporter training companions, which will be given to the companions of women in the postpartum…
- Conditions
- Postpartum, Fatigue, Depression, Social Support
- Trial name
- NCT06505733
- Testing
- postnatal attendant training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Body Image, Eating Disorder Symptom
Evaluation of the Impact of a Comic-based Programme to Promote Body Confidence Among Adolescents in India
Body dissatisfaction is a leading concern for young people and can have serious health consequences. Emerging approaches for improving body image are effective among adolescents in the school setting.
- Trial name
- NCT04317755
- Testing
- AdhaFULL body image comics
- Where
- United Kingdom
- Volunteers
- 2,631 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Malaria, Falciparum
Methylene Blue Against Falciparum Malaria in Burkina Faso
Safety of artesunate-amodiaquine combined with methylene blue or primaquine for falciparum malaria treatment in African children: A randomised controlled trial Elimination has become the goal of malaria programmes in an…
- Trial name
- BlueACTn (NCT02851108)
- Testing
- Methylene Blue, Primaquine
- Where
- Burkina Faso
- Volunteers
- 100 people
- Sponsor
- Heidelberg University
Irritable Bowel Syndrome, Dyspepsia Chronic
Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders
Abdominal pain (AP)-associated functional gastrointestinal disorders (FGIDs), particularly Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD), are common in pediatrics, and no safe and effective treatment is available.
- Trial name
- NCT02566876
- Testing
- Mixture of three Bifidobacteria
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Federico II University
Critical Illness
Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients.
A prospective, double-blinded, multicenter randomized control trial. All critically ill patients above 12 years of age requiring continuous sedation for >24hrs in the ICU will be screened and those meeting selection criteria (and…
- Trial name
- KeMiMof (NCT03407404)
- Testing
- Ketamine-Midazolam, Morphine -Midazolam
- Where
- Uganda
- Volunteers
- 124 people
- Sponsor
- Makerere University
Anxiety, Preoperative Anxiety
The Effect of Electric Ride-On Cars Use During Transport to the Operating Theatre
The aim of our study was to evaluate the effect of the use of a electric ride-on car during transport to the operating theatre on preoperative anxiety in children undergoing elective ambulatory surgery.
- Conditions
- Anxiety, Preoperative Anxiety, Pediatric Surgery
- Trial name
- NCT06303843
- Testing
- Transfer with an electric ride-on car
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Uşak University
Iron Deficiency, Anaemia in Children
A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of…
- Trial name
- IHAT-Gut (NCT02941081)
- Testing
- IHAT, Ferrous Sulphate
- Where
- The Gambia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Diabete Type 1, Educational Videos
Interactive Educational Video for Paediatric Type 1 Diabetes
The primary aim of this study is to evaluate the effectiveness of an interactive educational video (Luca's Journey: Managing Type 1 Diabetes) delivered in addition to the standard educational programme, in improving metabolic…
- Trial name
- Intedu (NCT07639307)
- Testing
- Interactive Educational Video (Luca's Journey: Managing Type 1 Diabetes), Traditional Face-to-Face Education
- Volunteers
- 110 people
- Sponsor
- G. d'Annunzio University
Nephrolithiasis, Staghorn Calculus
Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy
This study is a double blinded randomized controlled trial evaluating the impact of tranexamic acid use on the transfusion rate in patients with complex kidney stones undergoing percutaneous nephrolithotomy.
- Trial name
- NCT02966236
- Testing
- Tranexamic Acid
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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