Clinical trials: Randomised Controlled Trial
Psychological Disturbance, Anxiety Disorder of Childhood
An Experimental Study of Psychological Effect of School Based-Yoga on Low-Income School Children
Poverty is a common experience for many children and families in developing countries. Living in a poor or low-income household has been linked to poor health and increased risk for mental health problems than the general…
- Trial name
- NCT03960944
- Testing
- Yoga
- Where
- 3 sites in India
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Neonatal Encephalopathy, Newborn Asphyxia
Cooling in Mild Encephalopathy
The goal of this randomised control trial is to establish the safety and efficacy of whole-body hypothermia for babies with mild hypoxic ischaemic encephalopathy, inform national and international guidelines, and establish…
- Trial name
- COMET (NCT05889507)
- Testing
- Whole body hypothermia, Targeted normothermia, Supportive neonatal intensive care
- Where
- 39 sites in Italy, United Kingdom
- Volunteers
- 426 people
- Sponsor
- Imperial College London
Healthy
Assessment of an Electronic Voting System Within the Tutorial Setting. A Randomised Controlled Trial
A study of an electronic voting system as a learning aid during tutorials
- Trial name
- NCT00463944
- Testing
- Effect of an electronic voting system
- Where
- Australia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Malocclusion
Evaluation of Clinical and Patient-Reported Outcomes of Laceback
The goal of this clinical trial is to evaluate oral hygiene status, archwire complications, laceback complications, and pain while using lacebacks in patients undergoing orthodontic fixed appliance treatment.
- Trial name
- NCT07039071
- Testing
- Laceback
- Where
- Malaysia
- Volunteers
- 38 people
- Sponsor
- International Islamic University Malaysia
Measles Vaccine, Hospital Admission
Measles Vaccination at Health System Contacts
In addition to protecting against measles infection, measles vaccine (MV) strengthens the individual's ability to combat infections in general - MV has beneficial non-specific effects (NSE) lowering the risk of death and…
- Conditions
- Measles Vaccine, Hospital Admission, Mortality, Non-specific (Heterologous) Effects of Vaccines
- Trial name
- NCT04220671
- Testing
- measles vaccine, Saline
- Where
- Guinea-Bissau
- Volunteers
- 5,400 people
- Sponsor
- Bandim Health Project
Plantar Wart
Cryotherapy VS. Nitric-zinc Complex in the Treatment of Plantar Warts.
Plantar warts are benign skin lesions caused by human papillomavirus (HPV).There are several treatment methods for this illness, but none of them can heal all patients.
- Trial name
- NCT04654091
- Testing
- Cryoteraphy with liquid nitrogen, Nitric-zinc complex
- Volunteers
- 18 people
- Sponsor
- Universidad Complutense de Madrid
General Practice (GP), Primary Care Settings
Trial to Assess Implementation of New Research in a Primary Care Setting (TRAINS)
In England and Wales, unscheduled care for school-aged children with asthma significantly increases after their return to school in September, a trend linked with decreased asthma preventer prescriptions during the summer…
- Trial name
- (TRAINS) (NCT05226091)
- Testing
- Letter
- Where
- United Kingdom
- Volunteers
- 1,389 people
- Sponsor
- University of Sheffield
Cardiac Surgical Procedures, Blood Coagulation Disorders
Fibrinogen Concentrate In Children After Cardiac Surgery
The purpose of this study is to evaluate prospectively whether concentrate fibrinogen reduces blood losses, transfusion requirements and occurrence of clinical complications compared to cryoprecipitate in children after cardiac…
- Conditions
- Cardiac Surgical Procedures, Blood Coagulation Disorders, Fibrinogen, Cryoprecipitate
- Trial name
- FiCCS (NCT01187225)
- Testing
- Fibrinogen concentrate, Cryoprecipitate
- Where
- Brazil
- Volunteers
- 63 people
- Sponsor
- University of Sao Paulo
Alcohol Consumption, Violence
Violence Brief Intervention Pilot v1.1
This study is a randomised controlled trial of a new brief intervention with young (16-29) adult male patients who have a facial injury sustained as a result of interpersonal violence (fighting or assaults).
- Conditions
- Alcohol Consumption, Violence, Facial Injuries
- Trial name
- NCT02394990
- Testing
- Violence Brief Intervention, ABI
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- NHS Greater Glasgow and Clyde
Bacterial Pneumonia, Viral Pneumonia
Inhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial
The purpose of this study is to find out whether adjunct treatment with inhaled corticosteroids lead to faster improvement and reduce mortality of children under 5 years of age admitted to hospital with ALRI.
- Conditions
- Bacterial Pneumonia, Viral Pneumonia, Acute Asthma
- Trial name
- ICS (NCT01868113)
- Testing
- Inhaled corticosteroid
- Where
- Uganda
- Volunteers
- 1,010 people
- Sponsor
- Makerere University
Sepsis, Infection
RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates
Babies aged 0 to 90 days with a suspected infection requiring treatment with vancomycin will be recruited. They will be randomised to receive vancomycin as an intermittent infusion (over 1 hour) or as a continuous infusion (over…
- Conditions
- Sepsis, Infection, Bacteremia
- Trial name
- NCT02210169
- Testing
- Continuous infusion of vancomycin
- Where
- 2 sites in Australia
- Volunteers
- 111 people
- Sponsor
- Murdoch Childrens Research Institute
Cow's Milk Protein Allergy
Hydrolysed Rice Formula Study
This non-inferiority study aims to determine whether a hydrolysed rice protein formula is as effective as a cow's milk protein based extensively hydrolysed formula using a double-blind, randomised-controlled design over a 28-day…
- Trial name
- NCT06288503
- Testing
- Hydrolysed Rice Protein Formula, Cow's Milk Based Extensively Hydrolysed Formula
- Where
- 2 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Nutricia UK Ltd
Obesity
Family Based Intervention in Childhood obesitY
The study compares the effect on BMI of two different treatment options for obesity in childhood. Families with at least one obese child and parent are invited to join the project.
- Trial name
- NCT01110096
- Testing
- Parent Management Training - Oregon (PMTO), Motivational interviewing, Dynamic group therapy
- Where
- 2 sites in Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sykehuset i Vestfold HF
Cancer
DST in Reducing Depressive Symptoms, Enhancing Self-esteem, and Promoting Quality of Life Among CCSs
This study aims to examine the effectiveness of Digital storytelling (DST) in reducing depressive symptoms, enhancing self-esteem, and promoting quality of life among Chinese survivors of childhood cancer.
- Trial name
- NCT07052110
- Testing
- Digital storytelling
- Where
- Hong Kong
- Volunteers
- 248 people
- Sponsor
- The Hong Kong Polytechnic University
Adolescents With Obesity
This is a Study to Evaluate the Pharmacokinetics and Safety of IBI362 in Chinese Adolescents With Obesity
The study is a first-in-pediatric assessment of the safety, tolerability, and pharmacokinetic characteristics of multiple doses of IBI362 in Chinese adolescent subjects with obesity.
- Trial name
- NCT06536023
- Testing
- IBI362
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Asthma
Laminar Airflow in Severe Asthma for Exacerbation Reduction
To ascertain whether home-based nocturnal TLA usage over a 12 month period can reduce exacerbations and improve asthma control and quality of life as compared to placebo, whilst being cost-effective and acceptable to adults with…
- Trial name
- LASER (NCT03058497)
- Testing
- Temperature-Controlled Laminar Airflow Device (Airsonett®)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Infant, Very Low Birth Weight
High Protein and High Energy Intakes and Physical Activity on Growth of Extremely Low Birth Weight Infants
The aim of this study is to evaluate the effect of increasing amino acid and energy intake during parenteral and enteral nutrition with and without the stimulation of the infant's physical activity, on growth of extremely low…
- Trial name
- NCT03374033
- Testing
- NUTR +, STIMUL +
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università Politecnica delle Marche
Developmental Language Disorder and Language Impairment, Deprivation
Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial.
The overall aim of this clinical trial is to evaluate an at scale version of 'Happy Talk' in a large scale effectiveness study (examining inputs, outputs and outcomes) based on a sample of children from socially disadvantaged…
- Trial name
- HappyTalk (NCT06460090)
- Testing
- Happy Talk
- Where
- 4 sites in Ireland
- Volunteers
- 840 people
- Sponsor
- University College Cork
Obesity, Well-being
Activation of Young Men - Population-Based Randomised Controlled Trial
The aim of the study is to investigate different novel IC technologies for promoting physical activity and health and preventing obesity in young men.
- Conditions
- Obesity, Well-being, Quality of Life, Depression
- Trial name
- MOPO (NCT01376986)
- Testing
- physical, psychological and social activation
- Where
- Finland
- Volunteers
- 507 people
- Sponsor
- University of Oulu
Cystic Fibrosis
INSPIRE-CF: an Alternative Physiotherapy Model for Children With Cystic Fibrosis
The primary aim of the research is to evaluate whether an alternative model of cystic fibrosis (CF) physiotherapy care can produce statistically significant improvements in clinical and patient reported outcomes, and whether this…
- Trial name
- INSPIRE-CF (NCT01889927)
- Testing
- Exercise Intervention
- Where
- United Kingdom
- Volunteers
- 71 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
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