Clinical trials: Randomised Controlled Trial
Chronic Obstructive Pulmonary Disease
Glasgow Supported Self Management Trial (GSuST)
Training patients to alter their own therapy early in the course of a developing exacerbation (self-management) has been shown to improve outcomes in asthma, but there is no good evidence on this for patients with Chronic…
- Trial name
- GSuST (NCT00706303)
- Testing
- Supported self management training and support
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- NHS Greater Glasgow and Clyde
Virtual Reality, Anxiety
Effect of VR and Music on Fetal Well-Being and Anxiety During Nonstress Test
Music and virtual reality (VR) have been utilized in the medical field and are known to reduce anxiety and stress. However, a limited number of studies have investigated the effects of music and VR on women undergoing non-stress…
- Conditions
- Virtual Reality, Anxiety, Pregnancy, Randomised Controlled Trial
- Trial name
- NCT07082790
- Testing
- Music intervention, Virtual Reality Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Missed Miscarriage
Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Miscarriage is the most common complication of pregnancy. As many as 15-25% of pregnancies end in miscarriage, and the number of miscarriages in England is estimated to be approximately 125,000 per year.
- Trial name
- MifeMiso (NCT03065660)
- Testing
- Mifepristone, Oral, 200 Mg
- Where
- 28 sites in United Kingdom
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Colitis, Ulcerative
To Evaluate the Efficacy and Safety of FE 999315 in Japanese Subjects With Mild to Moderate Active Ulcerative Colitis
To demonstrate non-inferiority in efficacy of FE 999315 to mesalazine in patients with mild to moderate active ulcerative colitis after 8 weeks of treatment.
- Trial name
- NCT03412682
- Testing
- Budesonide (6 mg), Budesonide (9 mg), Mesalazine (3,600 mg)
- Where
- 72 sites in Japan
- Volunteers
- 274 people
- Sponsor
- Ferring Pharmaceuticals
Autism Spectrum Disorder
Improving Autistic Children's Experiences of Dental Care With Class-integrated Social Story
Children with autism spectrum disorder (ASD) are more likely to have unmet dental needs. Due to hypersensitivity and oral defensiveness, new or unexpected stimuli during dental examinations often precipitate anxiety and stress.
- Trial name
- NCT07166978
- Testing
- Social story
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- The University of Hong Kong
Scabies
Ivermectin Safety in Small Children
This trial will evaluate the safety, pharmacokinetics, and efficacy of ivermectin in scabies infected children weighing 5 to less than 15kg.
- Trial name
- ISSC (NCT04332068)
- Testing
- Oral ivermectin, Permethrin Cream
- Where
- 3 sites in Brazil, Kenya and 1 more
- Volunteers
- 240 people
- Sponsor
- University of Oxford
HIV Infections
Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe
The purpose of this study is to determine whether community-based peer education and condom distribution combined with improved treatment of sexually transmitted infections are effective in reducing the spread of HIV infection in…
- Trial name
- NCT00390949
- Testing
- Peer education among commercial sex workers and clients, Condom distribution and promotion, Syndromic treatment of sexually transmitted infections
- Where
- Zimbabwe
- Volunteers
- 9,454 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Premature Infant, Retinopaty of Prematurity
Effect of Multiple Non-pharmacological Methods for Pain Management During Eye Examination for Retinopathy of Prematurity in Preterm Infants
This study will be conducted to determine the effect on pain and vital signs of multiple nonpharmacological methods used in preterm infants during the examination for retinopathy of prematurity (ROP).
- Conditions
- Premature Infant, Retinopaty of Prematurity, Pain Management
- Trial name
- NCT06959290
- Testing
- Multiple nonpharmacological methods, Routine Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul Medeniyet University
Respiratory Hypersensitivity
Safety and Efficacy of House Dust Mite Allergoid in the Treatment of Bronchial Asthma
The trial is performed to assess efficacy and safety of the Allergopharma house dust mite allergoid in bronchial asthma.
- Trial name
- NCT00263640
- Testing
- Acaroid
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Allergopharma GmbH & Co. KG
Anorexia Nervosa
Trial of Enhanced Neurostimulation for Anorexia
Preliminary open-label studies have suggested that non-invasive brain stimulation methods of both transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS) have clinical benefits for…
- Trial name
- TRENA (NCT05788042)
- Testing
- MagPro TMS device (ARTG: 204659), tDCS mini-CT Stimulator (Soterix, USA: ARTG: 284637)
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The George Institute
Post Operative Pain
CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT
Pain is a subjective sensation which in children can only be experienced and most times not expressed. Pain management in children thus falls short of their adult counterparts.
- Trial name
- CaBuMorph (NCT02456142)
- Testing
- caudal bupivacaine, intravenous morphine
- Where
- Uganda
- Volunteers
- 70 people
- Sponsor
- Makerere University
Medical Education, Point of Care Ultrasound (POCUS)
Video-Based Versus Bedside eFAST Training in Final-Year Medical Students
This study compared two methods of teaching the Extended Focused Assessment with Sonography for Trauma (eFAST) examination to final-year medical students.
- Conditions
- Medical Education, Point of Care Ultrasound (POCUS), eFast
- Trial name
- NCT07790497
- Testing
- Standardized Video-Based eFAST Training, Instructor-Led Bedside eFAST Training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gorkem Alper Solakoglu
Growth Hormone Disorder, Growth Hormone Deficiency in Children
Investigating Efficacy and Safety of Once-weekly NNC0195-0092 Treatment Compared to Daily Growth Hormone Treatment (Norditropin® FlexPro®) in Growth Hormone Treatment naïve Pre-pubertal Children With Growth Hormone Deficiency
This trial is conducted globally. The aim of the trial is to investigate efficacy and safety of once-weekly NNC0195-0092 treatment compared to daily growth hormone treatment (Norditropin® FlexPro®) in growth hormone treatment…
- Trial name
- NCT02616562
- Testing
- somapacitan, Norditropin® FlexPro® pen
- Where
- 89 sites in United States, Austria and 12 more
- Volunteers
- 76 people
- Sponsor
- Novo Nordisk A/S
Asthma
Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma
The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution delivered via Respimat® inhaler (2.5 mcg and 5 mcg once daily) over 12 weeks, compared to placebo, as add-on controller therapy…
- Trial name
- NCT01277523
- Testing
- tiotropium high dose, tiotropium low dose
- Where
- 69 sites in United States, Argentina and 12 more
- Volunteers
- 392 people
- Sponsor
- Boehringer Ingelheim
Early Childhood Caries, Knowledge, Attitudes, Practice
Effectiveness of Strengthened Anticipatory Guidance Used in the MOH Malaysia Infant Oral Health Care Programme
This study aimed to assess the effectiveness of strengthened anticipatory guidance (AG) used in MOH Malaysia Infant Oral Healthcare Programme in preventing early childhood caries (ECC) lesions and improving caries risk of infants…
- Trial name
- MOH (NCT06000293)
- Testing
- Oral health education
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Allergic Asthma
Efficacy and Safety Trial of Subcutaneous Immunotherapy in Mite Induced Asthma
The purpose of this study is to determine whether a short course of subcutaneous immunotherapy is efficacious in mite induced asthma. The efficacy is based on reduction in control medication.
- Trial name
- NCT00492076
- Testing
- Pangramin Plus D. pteronyssinus 100%
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- ALK-Abelló A/S
Tobacco Industry Denormalisation Beliefs, Tobacco-related Communications
An RCT of a Smartphone-based TID Programme
The study aims to test the effect a smartphone-based intervention on primary school students and their parents' attitudes towards tobacco industry and their tobacco-related communications.
- Trial name
- NCT03342768
- Testing
- Smartphone-based messages
- Where
- Hong Kong
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gestational Diabetes
Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus
GUARD is a Clinical Trial that wants to explore the impact of UDCA compared to metformin in the treatment of GDM. The trial wants to recruit 158 women who are overweight or obese who have been diagnosed with GDM, and require…
- Trial name
- GUARD (NCT04407650)
- Testing
- Metformin, Ursodeoxycholic Acid
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- King's College London
Infantile Colic
An Infant Formula Trial on Dietary Management of Infantile Colic
A randomised, double blind, controlled, multi-centre study to assess the efficacy of an infant formula in the dietary management of infantile colic.
- Trial name
- NCT03329222
- Testing
- Specific hydrolysed proteins, Standard cow's milk with prebiotics mixture
- Where
- 2 sites in Singapore, Thailand
- Volunteers
- 5 people
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Prematurity, Respiratory Failure
Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation
Non-invasive respiratory support has been emerging in the management of respiratory distress syndrome (RDS) in preterm infants to minimise the risk of lung injury.
- Conditions
- Prematurity, Respiratory Failure, Ventilator Lung; Newborn
- Trial name
- NCT03388437
- Testing
- NI-NAVA, NIPPV
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Fahad Armed Forces Hospital
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