Clinical trials: Randomised Controlled Trial
Stuttering in Adolescence, Bullying of Child
The Classroom Communication Resource (CCR) Intervention to Change Grade 7 Peer's Attitudes Towards Children Who Stutter (CWS)
Children who stutter (CWS) are at high risk of being teased and bullied in primary school because of the negative peer attitudes and perceptions towards stuttering.
- Trial name
- CCR (NCT03111524)
- Testing
- Classroom Communication Resource, No intervention
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Rizwana Mallick
Child Malnutrition
Efficacy of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia
The purpose of this trial is to evaluate the efficacy of the LNS on children aged 6-17 months in preventing growth faltering and improving micronutrient status.
- Trial name
- NCT02257762
- Testing
- LNS, Corn-soy blend ++ (CSB++), Sprinkles
- Where
- Cambodia
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement, Cambodia
Hysterectomy, PLISSIT Model
The Effect of Sexual Counselling Based on PLISSIT and BETTER Model After Hysterectomy
Sexuality is affected by several physiological, cultural, social, and psychological factors. Hysterectomy is one of the factors that affects sexuality. Evidence suggests that hysterectomy, affects the sexual function of women.
- Conditions
- Hysterectomy, PLISSIT Model, Sexual Health Quality of Life, Sexual Function
- Trial name
- NCT06609096
- Testing
- Sexual counseling based on the PLISSIT model, Sexual counseling based on the BETTER model
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Kutahya Health Sciences University
Type 1 Diabetes Mellitus
CBT in Adolescents With Type 1 Diabetes
The effectiveness of cognitive behavioural therapy (CBT) for adolescents with type 1 diabetes will be tested. This structured, time-limited, problem-orientated therapy will be used to impact on psychosocial factors influencing…
- Trial name
- NCT00360061
- Testing
- Cognitive Behaviour Therapy
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Bristol
Gestational Diabetes, Type 2 Diabetes Mellitus
Face-it: Health Promotion for Women With Prior Gestational Diabetes
This project focuses on evaluating a health promotion intervention among families where the mother has prior gestational diabetes mellitus (GDM) in the first year after delivery.
- Conditions
- Gestational Diabetes, Type 2 Diabetes Mellitus, Quality of Life
- Trial name
- Face-it (NCT03997773)
- Testing
- Face-it Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 277 people
- Sponsor
- Steno Diabetes Center Copenhagen
Metabolism and Nutrition Disorder, Obesity
Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With Obesity
This trial is conducted globally. The aim of this trial is to investigate the effect of liraglutide for weight management in pubertal adolescent subjects with obesity.
- Trial name
- NCT02918279
- Testing
- Liraglutide
- Where
- 33 sites in United States, Belgium and 3 more
- Volunteers
- 251 people
- Sponsor
- Novo Nordisk A/S
HIV
Male Circumcision Against HIV Hukomboa
Tanzania launched a National Strategy for scaling-up voluntary medical male circumcision in 2010, and aims to circumcise 2.8 million males by 2015.
- Trial name
- NCT02376348
- Testing
- A targeted demand creation Activities
- Where
- 2 sites in Tanzania
- Volunteers
- 10,782 people, healthy volunteers welcome
- Sponsor
- National Institute for Medical Research, Tanzania
Cannabis Use Disorder
Guanfacine Extended-release for Adolescents With Cannabis Use
A randomized controlled trial to assess the efficacy of extended-release guanfacine to reduce cannabis use frequency in young people with cannabis use disorder following a period of monitored abstinence.
- Trial name
- GRACE (NCT05957848)
- Testing
- Guanfacine Extended Release Oral Tablet, Residential withdrawal, Engagement with alcohol and other drug services
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Orygen
Metabolism and Nutrition Disorder, Obesity
A Trial to Assess the Effects of Liraglutide on Gallbladder Emptying in Overweight and Obese Subjects.
This trial is conducted in Europe. The aim of this trial is to investigate the effects of liraglutide on gallbladder emptying in overweight and obese subjects.
- Trial name
- NCT02717858
- Testing
- liraglutide
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Novo Nordisk A/S
Asthma
Clinical Trial of Fluticasone Versus Placebo at the Onset of a Cold for Children With Asthma
The purpose of this study is to determine, in children aged 1 to 6 years with recurrent asthma induced by upper respiratory tract infections (URTI), whether the administration of high doses of inhaled fluticasone started at the…
- Trial name
- NCT00238927
- Testing
- inhaled fluticasone 750 mcg/day twice daily until 2 days without symptoms (maximum 15 consecutive days)
- Where
- 5 sites in Canada
- Volunteers
- 150 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Menstrual Hygiene Management
Does Menstrual Hygiene Matter? Investigating the Impact of a Menstrual Hygiene Program on Ugandan Girls' School Absenteeism
This study builds on the pilot work of the Irise research group to investigate the impact of menstrual hygiene interventions on East African girls' school attendance, activities of daily living and self-esteem.
- Trial name
- NCT02243488
- Testing
- Irise Easy Pad & Menstrual Health Education
- Where
- Uganda
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Irise International
Postoperative Pain Management
Pain Treatment After TKA With LIA and Intra-articular Continuous Infusion Pump
The purpose of this study is to evaluate the effect on postoperative pain and function by adding intraarticular continuous infusion pump with local anesthetic after total knee arthroplasty where local infiltration analgesia has…
- Trial name
- NCT01726686
- Testing
- Ropivacaine
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Asthma Childhood, Respiratory Muscle Training
Effects of Expiratory Muscle Training in Children With Asthma: A Randomised Controlled Trial
The goal of this randomized clinical trial is to evaluate the effectiveness of expiratory muscle training (EMT) as an adjunct to conventional chest physiotherapy in children with asthma.
- Trial name
- NCT07169071
- Testing
- Home-based chest physiotherapy program, Expiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Critical Illness, Sepsis
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
Introduction- Hospital acquired infections (HAI) are a major cause of morbidity and mortality and increase health care costs. Critically ill patients are particularly susceptible to these infections and have an even higher…
- Conditions
- Critical Illness, Sepsis, Septic Shock, Ventilator Associated Pneumonia
- Trial name
- SuDDICU (NCT02389036)
- Testing
- SDD Oral Paste, SDD Gastric Suspension, Intravenous Antibiotic
- Where
- 3 sites in Australia, Canada and 1 more
- Volunteers
- 20,010 people
- Sponsor
- The George Institute
Myopia, Myopia Progression
The A.R.R.E.S.T.® Spectacle Film Study
The goal of this clinical trial is to learn if spectacle films using Active Reconfiguration in Retinal Encoding of Spatio-Temporal (A.R.R.E.S.T.®) signal technology works to slow down the rate of myopia progression in myopic…
- Trial name
- NCT06692699
- Testing
- Single vision spectacle lens, A.R.R.E.S.T. spectacle film
- Where
- Vietnam
- Volunteers
- 123 people
- Sponsor
- nthalmic Pty Ltd
Respiratory Tract Infections, Pediatric Respiratory Diseases
Bacterial Lysate In Preventing Asthma
Bronchiolitis is a common viral infection of the small airways of infants and some affected infants will require hospital admission.
- Conditions
- Respiratory Tract Infections, Pediatric Respiratory Diseases, Wheezing
- Trial name
- BLIPA (NCT05064631)
- Testing
- Bacterial Lysate
- Where
- 3 sites in United Kingdom
- Volunteers
- 173 people
- Sponsor
- Queen Mary University of London
Asthma
Randomised Controlled Trial of a Multi-faceted Community-based Intervention to Improve Asthma in Children
The objectives of this trials are to demonstrate, in children with poorly controlled asthma, that an intervention to increase the awareness and the impact of poor asthma control among parents and physicians of affected children…
- Trial name
- NCT00238888
- Testing
- asthma control awareness, Usual care
- Where
- Canada
- Volunteers
- 298 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Thromboprophylaxis
Apixaban to Prevent Venous Thromboembolism in Ambulatory Lung Cancer Patients Undergoing Systemic Anticancer Treatment
The aim of this trial is to find out if a tablet called apixaban can reduce blood clots in people with lung cancer having chemotherapy or similar treatments.
- Trial name
- THROMBO-STOP (NCT07160686)
- Testing
- Apixaban
- Where
- 8 sites in United Kingdom
- Volunteers
- 1,456 people
- Sponsor
- University of Birmingham
Abortion Early
Very Early Medical Abortion
The research question begin addressed by this study is "Is Very Early Medical Abortion (VEMA - before a pregnancy is visible on ultrasound scan) as effective as medical abortion when performed later and an intrauterine pregnancy…
- Trial name
- VEMASCOT (NCT03989869)
- Testing
- Immediate treatment
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Treatment, Growth Modification
Study of The Effects of Mandibular Advancement Aligners in Treating Children With Class II Division 1 Malocclusion
The goal of this clinical trial is to learn the effects of Mandibular Advancement Aligner in growth modification of children with Class II Division 1 malocclusion.
- Trial name
- NCT07420270
- Testing
- Mandibular Advancement Aligner
- Where
- Malaysia
- Volunteers
- 21 people
- Sponsor
- University of Malaya
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