Clinical trials: Randomised Controlled Trial
Atopic Dermatitis
Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? the D-Vex Pilot Study
Vitamin D is known to have a regulatory influence on both the immune system and skin barrier function. Studies in paediatric populations have found an inverse association of vitamin D levels and with both prevalence and severity…
- Trial name
- D-Vex (NCT03257215)
- Testing
- Stoss vitamin D, Daily vitamin D
- Where
- Australia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Knee Osteoarthritis
The McKenzie System With Arthritic Knees: Do Some Knees Respond to Specific Exercise More Than General or no Exercise
The purpose of the study is to explore if a subgroup of people with osteoarthritic knees can be identified using the McKenzie System of Mechanical Diagnosis and Therapy.
- Trial name
- NCT01641874
- Testing
- Exercise, Evidence based exercise
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cancer
DST in Reducing Depressive Symptoms, Enhancing Self-esteem, and Promoting Quality of Life Among CCSs
This study aims to examine the effectiveness of Digital storytelling (DST) in reducing depressive symptoms, enhancing self-esteem, and promoting quality of life among Chinese survivors of childhood cancer.
- Trial name
- NCT07052110
- Testing
- Digital storytelling
- Where
- Hong Kong
- Volunteers
- 248 people
- Sponsor
- The Hong Kong Polytechnic University
Role, Nurses
Clarification of Nurses' Expected Role in Health Promotion
The purpose of this study is to implement and evaluate ROLE-AP, a multi-component program to clarify primary care nurses' expected role in health promotion.
- Trial name
- ROLE-AP (NCT04726696)
- Testing
- ROLE-AP programme
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Full Thickness Macular Hole
Pilot Randomised Controlled Trial of Posturing Following Surgery for Full-thickness Macular Hole
This is a pilot randomised controlled trial (RCT) to investigate the effect of postoperative face-down positioning on the outcome of macular hole surgery.
- Trial name
- NCT01226160
- Testing
- Postoperative face-down posturing, Postoperative non-posturing group
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Time-Loss Injury Incidence
Effects of an ACWR-Guided Load Management Intervention on Time-Loss Injury Incidence in Chinese Elite Youth Footballers: A Cluster Randomised Controlled Trial
This cluster-randomised controlled trial aims to evaluate whether a multi-component load management intervention-incorporating real-time acute:chronic workload ratio (ACWR) feedback, automated alerts, coach education, and…
- Trial name
- ACWR Injury (NCT07727382)
- Testing
- ACWR-guided load management
- Volunteers
- 847 people, healthy volunteers welcome
- Sponsor
- Xinyang Agriculture and Forestry University
Foetal Growth Problem, Small for Gestational Age
Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)
This study is conducted in Japan. The aim of this trial is to assess the efficacy and safety of somatropin in children born small for gestational age (SGA) in Japan.
- Trial name
- NCT00184717
- Testing
- somatropin
- Where
- Japan
- Volunteers
- 98 people
- Sponsor
- Novo Nordisk A/S
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital
Obesity
SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity
The study looks at how liraglutide works on participant's body weight. Researchers will look at how liraglutide can help children with obesity to lose weight.
- Trial name
- NCT04775082
- Testing
- Liraglutide
- Where
- 32 sites in United States, Belgium and 7 more
- Volunteers
- 78 people
- Sponsor
- Novo Nordisk A/S
Eating Behavior, Healthy Diet
PROFRUVE Program to Promote Fruit and Vegetables Intake Among Children.
Because fruit and vegetables (FV) intake of children of Vitoria city is low, a controlled intervention program was proposed at school level.
- Conditions
- Eating Behavior, Healthy Diet, Fruit and Vegetable Intake, Childhood Obesity
- Trial name
- PROFRUVE (NCT03400891)
- Testing
- Program based on the theory of planned behaviour
- Volunteers
- 230 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Dementia, Delirium
The Effect of a Pre- and Postoperative Orthogeriatric Service
The investigators' aim is to assess the effect of a model of preoperative as well as early postoperative care, treatment and rehabilitation in a dedicated orthogeriatric ward in a single-blind randomised study.
- Trial name
- NCT01009268
- Testing
- Orthogeriatric intervention
- Where
- Norway
- Volunteers
- 332 people
- Sponsor
- Ullevaal University Hospital
Autism Spectrum Disorder
Improving Autistic Children's Experiences of Dental Care With Class-integrated Social Story
Children with autism spectrum disorder (ASD) are more likely to have unmet dental needs. Due to hypersensitivity and oral defensiveness, new or unexpected stimuli during dental examinations often precipitate anxiety and stress.
- Trial name
- NCT07166978
- Testing
- Social story
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- The University of Hong Kong
Language Development
Reading Together: How to Promote Children's Language Development Using Family-based Shared Book Reading
The aim of this project is to determine how shared reading promotes child language development, and to use this knowledge to make it an effective language-boosting tool for children from all social and economic backgrounds.
- Trial name
- NCT02625584
- Testing
- Reading Together - Pausing for Reading, Reading Together - Dialogic Reading, Reading Together - Shared Reading Control
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Caroline Rowland
Asthma
Trial of Vitamin D Supplementation in Asthma
The study null hypothesis is that vitamin D supplementation will not influence time to upper respiratory tract infection or time to severe asthma exacerbation in adult and adolescent patients with asthma.
- Trial name
- ViDiAs (NCT00978315)
- Testing
- Cholecalciferol, Miglyol oil
- Where
- 4 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Barts & The London NHS Trust
Telemedicine, Emergency Medical Service
Audiovisual Consultations in Prehospital Emergency Care: Randomised Controlled Trial
This study investigates safety and efficacy of the use of audiovisual consultations of emergency medical service (EMS) doctor by paramedics for low urgency events in areas covered with paramedic crews only from emergency medical…
- Trial name
- Telemedicine (NCT04312321)
- Testing
- Mandatory phone call consultation, Mandatory audiovisual consultation
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Obesity, Overweight
Early Stockholm Obesity Prevention Program
To study whether a targeted intervention can prevent the development of overweight and obesity among pre-school children in families with either one obese or two overweight parents.
- Trial name
- EarlySTOPP (NCT01198847)
- Testing
- Dietary, physical activity and sleeping
- Where
- Sweden
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Attention Deficit Hyperactivity Disorder (ADHD)
Assessing QbTest Utility in ADHD: A Randomised Controlled Trial
Attention Deficit/Hyperactivity Disorder (ADHD)is one of the most common mental health disorders of childhood. Children with ADHD often have poor attention, are restless and hyperactive and show impulsive behaviour.
- Trial name
- AQUA2 (NCT02209116)
- Testing
- Qb Test
- Where
- 9 sites in United Kingdom
- Volunteers
- 267 people
- Sponsor
- University of Nottingham
Juvenile Dermatomyositis
Five-year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis
This is a 5-year project, involving 185 partners from 46 countries ((110 in 21 European Union (EU) States and 75 in 25 extra-EU States)), with a randomised clinical trials (RCT) in juvenile dermatomyositis (JDM): 5-year phase III…
- Trial name
- PRINTOJDMTR (NCT00323960)
- Testing
- 3 MPDN pulse + PDN, 3 MPDN pulse + PDN + CSA, 3 MPDN pulse + PDN + MTX
- Where
- Italy
- Volunteers
- 139 people
- Sponsor
- Istituto Giannina Gaslini
Cow Milk Allergy, Food Allergy
Effectiveness and Safety of Milk Ladders in Children with IgE-Mediated Cow's Milk Protein Allergy
Cow's milk protein allergy (CMPA) is one of the most common food allergies in early childhood. The first-line treatment of CMPA is the elimination of cow's milk proteins (CMPs) from the child's or maternal diet.
- Trial name
- NCT06664918
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 92 people
- Sponsor
- Medical University of Warsaw
Body Image
A Trial of Three School-based Body Image Interventions Delivered by Teachers
Body image is one of the leading concerns for young people. Such concerns can have serious health consequences, including unhealthy weight control and exercise behaviours, depression, smoking, low self-esteem and misusing drugs…
- Trial name
- NCT03286478
- Testing
- Mindfulness, Dissonance, Dove Confident Me
- Where
- United Kingdom
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of the West of England
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