Clinical trials: Refractive Error
Myopia
Myopia Control With Simultaneous Vision Approach
To determine if the 'Defocus Incorporated Soft Contact' (DISC) lens slows myopia progression in Hong Kong schoolchildren using simultaneous vision approach.
- Trial name
- NCT00919334
- Testing
- Defocus Incorporated Soft Contact (DISC) lens
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
Myopia, or shortsightedness, is a multifactorial disorder, governed by environmental and genetic factors. Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades and affecting…
- Trial name
- MODERATO (NCT07028827)
- Testing
- 0.05% atropine eye drops, 0.025% atropine eye drops
- Where
- 11 sites in Albania, Italy and 3 more
- Volunteers
- 234 people
- Sponsor
- Ocus Innovation Ireland Limited
Myopia
Retinal Oxygen Metabolism in Children With Myopia
The aim of the present study is to gain more information about retinal functional parameters in myopic children in Europe. For this purpose, a prospective case-control study in children aged between 8 and 13 years, as this is the…
- Trial name
- NCT07473401
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Cataract
Total Corneal Astigmatism Prevalence in Cataract Patients
The purpose of this study is to report the prevalence data for total corneal astigmatism (TCA) in cataract surgery candidates.
- Trial name
- NCT06148857
- Testing
- IOLMaster 700
- Where
- China
- Volunteers
- 11,000 people
- Sponsor
- Peking University Third Hospital
Myopia
A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
The objective of this study is to determine whether the remote monitoring of myopia patients with the EyeQue Insight (visual acuity test) can replace regularly scheduled follow-up visits.
- Trial name
- NCT04693260
- Testing
- Visual Acuity with a Hand-held Device Supported by Mobile App.
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia
Study of Atropine Sulfate Eye Drops(0.01%) in Treating Near-work-induced Transient Myopia in Children
This study is a randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of atropine sulfate eye drops (0.01%) in treating transient myopia induced by near work tasks (NITM) in…
- Trial name
- NCT06697522
- Testing
- Atropine Sulfate
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Ocumension Therapeutics (Suzhou) Co., Ltd
Cataract
Longitudinal Changes in Refractive Error After Primary IOL Implantation Among Children With Congenital Cataract
The purpose of prospective cohort study is to estimate the rate of change in postoperative change after primary IOL implantation among children with congenital cataract(CC) and to explore key factors associated with the rate of…
- Trial name
- NCT04441268
- Testing
- primary IOL implantation
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Sun Yat-sen University
Cataract, High Myopia
Artificial Intelligence for Highly Myopic Cataract
This study aims to establish a multi-center artificial intelligence model for the accurate calculation of intraocular lens and its clinical application in highly myopic cataract, so as to improve the accuracy of the prediction of…
- Conditions
- Cataract, High Myopia, Myopia, Automatic Judgement
- Trial name
- AI-HMC (NCT06616506)
- Testing
- newly-invented AI model
- Where
- China
- Volunteers
- 500,000 people
- Sponsor
- Shanghai High Myopia Study Group
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Dehydration of Omafilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366910
- Testing
- omafilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- CooperVision, Inc.
Myopia
Assessment of Daily Disposable Silicone Hydrogel Lens Wear
The purpose of this study is to evaluate the effect of an investigational silicone hydrogel soft contact lens on new contact lens wearers (neophytes) compared to a control of spectacle wearers.
- Trial name
- NCT01093625
- Testing
- Narafilcon B Contact Lens, Spectacles
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Keratoconus, Keratoconus, Artificial Intelligence, Support Vector Machine
Predicting Manifest Astigmatism in Keratoconus Patients.
The cornea of the human eye has several functions. It is transparent to allow light into the eye and its shape focuses the incoming light onto the retina.
- Trial name
- NCT06798779
- Testing
- Glasses, Corneal topography
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Cycloplegia, Refractive Errors
Cycloplegic Refraction in Pediatric Patients With Esotropia
The primary outcome of this study is to compare cyclopentolate 1% and tropicamide 1% for cycloplegic refractions in pediatric populations with esotropia.
- Conditions
- Cycloplegia, Refractive Errors, Esotropia, Vision Disorders
- Trial name
- NCT06077682
- Testing
- Cyclopentolate, Tropicamide
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Islamic Hospital, Jordan
Retinopathy of Prematurity, Myopia
Prematurity and Ophthalmological Changes
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
- Trial name
- NCT06452524
- Testing
- axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Astigmatism
Clinical Comparison of Two Silicone Hydrogel Toric Lenses in the US
The purpose of this trial is to compare the performance of two different contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01007812
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 50 people
- Sponsor
- CIBA VISION
Myopia
Assessment of the Efficacy and Safety of a DYnaMic Peripheral DegradatiON Myopia Disorder Control in Myopic Children ״DYMOND Study״
The DYMOND study evaluates the safety and effectiveness of TrackSight™, a digital medical application designed to slow myopia (nearsightedness) progression in children during everyday screen use.
- Trial name
- DYMOND (NCT07390500)
- Testing
- TrackSight
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- NovaSight
Presbyopia
The C-MAC Video Laryngoscope Helps Presbyopic Anesthetists
Endotracheal intubation is the de facto gold standard for airway management especially in neonatal and pediatric anesthesia . An efficient neonatal airway management is challenging even in the most experienced hands and the…
- Trial name
- NCT06581705
- Testing
- Video Laryngoscope
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Egymedicalpedia
Obesity, Myopia
Beijing (Peking)---Myopia and Obesity Comorbidity Intervention (BMOCI)
Based on the RE-AIM framework, this project intends to integrate the prevention and control measures of myopia and obesity, and establish a set of key suitable technical packages and guarantee systems for the…
- Trial name
- NCT05275959
- Testing
- A cluster randomized trial of a comprehensive intervention nesting family and clinic into school centered implementation to reduce myopia and obesity among children and adolescents in Beijing, China
- Where
- 3 sites in China
- Volunteers
- 3,963 people, healthy volunteers welcome
- Sponsor
- Peking University
Pediatric Cataract, IOL Implantation
Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery
Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the…
- Conditions
- Pediatric Cataract, IOL Implantation, Myopia Progression
- Trial name
- NCT07364370
- Testing
- Atropine Eye drops
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University