Clinical trials: Reproductive Disorder
Autism Spectrum Disorder
Evaluation of Skillflix for Parents of Youth With ASD
The goal of this clinical trial is to evaluate the effectiveness of using a Microskills video training library for training parents of adolescents with ASD in talking with their teens about relationships and sexual health topics.
- Trial name
- NCT05958394
- Testing
- SkillFlix for Parents
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ashley Philliber
Streptococcus Suis Infection
Human Suis and Pig Diseases in Northern Vietnam
This study aim to test the hypothesis that human S.suis infections are associated in time and space with outbreaks of Porcine Reproductive and Respiratory Syndrome (PRRS) virus or other diseases in pigs.
- Trial name
- NCT01434719
- Where
- Vietnam
- Volunteers
- 273 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Bipolar Disorder
Reproductive Function in Women With Bipolar Disorder
Many studies have shown that patients with bipolar disorder are prone to reproductive dysfunction, including polycystic ovary syndrome, hyperprolactinemia, and amenorrhea.
- Trial name
- NCT05307848
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Klinefelter Syndrome
Long-term Systematic Follow-up of Patients With Klinefelter Syndrome Followed at the Department of Growth and Reproduction, Rigshospitalet
Klinefelter syndrome (KS) is the most frequent sex chromosome disorder affecting approximately 1:660 newborn boys. The prevalence of KS rises to 3-4% among infertile males and 10-15% in patients with non-obstructive azoospermia.
- Trial name
- FOXXY (NCT07142135)
- Testing
- There is no intervention, only clinical description
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Reproductive Health
RH and Adolescents
This study will create a model of reproductive health services for HIV-positive female adolescents in Asia.
- Trial name
- NCT02713750
- Testing
- reversible contraceptive methods
- Where
- 4 sites in Thailand
- Volunteers
- 77 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Chagas Disease
Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age
The investigators are proposing to perform a double-blinded, non-inferiority randomized controlled trial comparing a short 30-day treatment with BZN 150mg/day (30d/150mg) vs. a 60-day treatment with BZN 300 mg/day (60d/300mg).
- Trial name
- BETTY (NCT03672487)
- Testing
- Benznidazole
- Where
- 3 sites in United States, Argentina
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Public Health and Tropical Medicine
Infertility
An Observational Study to Evaluate Efficacy, Safety and Clinical Outcomes of Currently Used Pharmaceutical Therapies for Controlled Ovarian Stimulation in Assisted Reproductive Techniques
Human gonadotrophins have been successfully used for the treatment of infertility for more than 30 years. This observational study is being conducted to evaluate the efficacy and safety of the gonadotropins used for controlled…
- Trial name
- ESCORT (NCT01149070)
- Where
- Hungary
- Volunteers
- 10,103 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
US Eeva™ Pregnancy Investigational Clinical Study (US EPIC)
The purpose of this clinical investigation is to gather data to evaluate the impact of using Eeva with traditional morphology grading on implantation rates.
- Trial name
- US EPIC (NCT01671657)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Progyny, Inc.
Sexually Transmitted Infections, Pregnancy, Unplanned
Optimizing a Multi-Modal Intervention to Reduce Health-Risking Sexual Behaviors: Component Selection
The goal of this project is to evaluate the components of the app-based intervention Mission Wellness to reduce health-risking sexual behaviors (HRSBs; e.g., condom non-use, multiple sexual partners) in active-duty members of the…
- Conditions
- Sexually Transmitted Infections, Pregnancy, Unplanned, Military Personnel
- Trial name
- NCT04661566
- Testing
- Basic Education ("Education"), Narrative Videos ("Narratives"), Skills Building Videos ("Skills")
- Where
- United States
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Hypogonadotropic Hypogonadism, Kallmann Syndrome
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders
The aims of this study are: 1) to identify genes that play a role in human pubertal development and reproduction, 2) to characterize the phenotypic spectrum of patients with these gene defects, and 3) to discern the mode of…
- Conditions
- Hypogonadotropic Hypogonadism, Kallmann Syndrome, Puberty, Delayed, Puberty, Precocious
- Trial name
- NCT00494169
- Where
- United States
- Volunteers
- 4,042 people
- Sponsor
- Massachusetts General Hospital
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Sexually Transmitted Diseases, Reproductive Behavior
Enhanced SexHealth Intervention to Improve Adolescent Outcomes
This is an adaptive trial with an initial Formative Revision Process followed by a Randomized Controlled Trial (RCT). Up to 500 adolescents will be consented into this study to achieve 6 completed subjects for the formative…
- Trial name
- NCT03341975
- Testing
- SexHealth
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Systemic Lupus Erythematosus
Saphnelo Use in Females of Child-bearing Potential
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by substantial clinical burden-including organ damage, increased morbidity, and mortality-that often presents in young adulthood and…
- Trial name
- PRIMULA DUS (NCT07431775)
- Testing
- Anifrolumab
- Volunteers
- 26,000,000 people
- Sponsor
- AstraZeneca
Epilepsy
Effect of Valproate Versus Levetiracetam Monotherapy on Reproductive Functions in Epileptic Males
Background: Different antiepileptic drugs are responsible for reproductive dysfunction in male epileptic patients. The aim of this study is to evaluate the effect of valproate versus levetiracetam as a monotherapy on males' sex…
- Trial name
- NCT03953781
- Testing
- Effect of valporate on Reproductive Functions in Newly Diagnosed Epileptic Males, Effect of levetiracetam on epileptic males reproductive function
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Reproductive Health, Contraception
Personal Responsibility Education Program Innovative Strategies: Digital Initiative for Youth
This randomized control trial (RCT) will assess an innovative demonstration project to improve adolescent sexual and reproductive health among highly mobile and marginalized youth in Fresno County, California.
- Conditions
- Reproductive Health, Contraception, Sexually Transmitted Diseases
- Trial name
- PREIS (NCT03765255)
- Testing
- In the Know: sexual health education
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Therapeutic Abortion With Complications, Personality Disorders
Therapeutic Termination of Pregnancy and Psychiatric Implications
25 parental couples, with a prenatal diagnosis of fetal abnormality, had psychiatric evaluation for eligibility before TToP and after one year from the procedure.
- Conditions
- Therapeutic Abortion With Complications, Personality Disorders, Trauma, Psychological, Reproductive Behavior
- Trial name
- TTOP_PSY (NCT04080141)
- Testing
- Multiple psychometric questionnaire, Clinical psychiatric examination
- Volunteers
- 90 people
- Sponsor
- University of Milano Bicocca
Contraceptive Behavior, Sexually Transmitted Diseases
The Young Woman's Reach Project: Trial of an Intervention to Impact Contraceptive Behavior, Unintended Pregnancy, and Sexually Transmitted Infections (STIs) Among Adolescent Females
The New Generation Health Center/University of California, San Francisco (UCSF) will implement an intervention to impact contraceptive behavior and reduce unintended pregnancy and sexually transmitted infections (STIs) among…
- Trial name
- REACH (NCT00230880)
- Testing
- follow-up phone counseling
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of California, San Francisco
Infertility, Mental Health
Patient Empowerment Project (PEP) Study
The Patient Empowerment Project (PEP) will be integrated into the intake process at a fertility clinic to prepare clinical staff for any patient sensitivities or preferences and provide extra support if needed.
- Trial name
- PEP (NCT07725458)
- Testing
- Patient Empowerment Program (PEP)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Inception Fertility Research Institute, LLC