Clinical trials: Resorption
Root Resorption, Orthodontic Appliance
Three-dimensional CBCT Analysis of Root Volume Changes Following Tooth-bone and Bone-borne Maxillary Expansion: A Pilot Study.
External root resorption (ERR) is an undesired side effect observed after rapid maxillary expansion (RME). This study aimed to investigate changes in the root volume of maxillary permanent first molars after RME using tooth-borne…
- Conditions
- Root Resorption, Orthodontic Appliance, CBCT Segmentation
- Trial name
- NCT06912568
- Testing
- Miniscrew insertion, Expander, CBCT
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Osteoporosis
Assessment of Anti-RANKL Antibody in Post-menopausal Women
This is a single-center, open-label, dose-escalating study to evaluate the safety, pharmacokinetics, immunogenicity, and preliminary efficacy of single dose subcutaneous injection of a fully human monoclonal antibody of receptor…
- Trial name
- NCT03242512
- Testing
- TK006
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu T-Mab Biopharma Co.,Ltd
Alveolar Bone Loss
Comparison of Coronally Advanced Lingual Flap to Modified MPI for Flap Advancement in Partially Edentulous Patients
Comparison of cronally advanced lingual flap to modified periosteal releasing incision (MPRI)
- Trial name
- NCT03466840
- Testing
- The coronally advanced lingual flap, Modified periosteal releasing Incision
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillofacial Bone Defect, Alveolar Bone Loss
Bone Marrow Mononuclear Cells for the Repair of Severe Maxillofacial Bone Defects
This is a single-center, single-arm, open-label clinical study conducted at the Department of Stomatology, Nanjing Drum Tower Hospital.
- Trial name
- NCT07852806
- Testing
- Autologous bone marrow-derived mononuclear cells (BMMNCs), Bio-Oss bone graft material with collagen membrane
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Orthodontic Treatment
Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
The objectives if this study was to evaluate the efficacy of 3 different rectangular archwires in the correction of the curve of Spee (COS), to record the time needed to level excessive COS in the mandibular arch using the 3…
- Trial name
- NCT04549948
- Testing
- 0.017X0.025 Stainless steel, 0.019X0.025 Stainless steel, 0.021X0.025 B-Titanium archwire
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Bone Health, Nutrition Status
Optimizing Vitamin D Status During Initial Military Training
The primary objective of this randomized, double-blind, placebo-controlled trial is to determine the effect of vitamin D and calcium supplementation (800IU and 2000mg, respectively) on biochemical indicators of nutritional status…
- Trial name
- NCT01617109
- Testing
- Ca/Vit D
- Where
- 2 sites in United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Implant, Analgesia
Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia
Study hypothesis: Low level laser (LED) will reduce initial bone resorption and improve primary stability of dental implant. It will also reduces post operative pain compared to patient without treatment Implant osseointegration…
- Trial name
- NCT01097499
- Testing
- OsseoPulse device (Light emitting diode technology)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Malocclusion of Anterior Teeth, Malocclusion; Displaced Teeth
Effects of Three Orthodontic Archwire Protocols on Root and Bone Changes
This randomized controlled clinical trial compares the effects of three orthodontic archwire protocols used during the alignment phase on anterior tooth roots and the supporting alveolar bone.
- Trial name
- NCT07688655
- Testing
- Square-shaped cross-sectional archwire, Rectangular-shaped cross-sectional archwire, Traditional sequence of archwires
- Where
- Syria
- Volunteers
- 53 people
- Sponsor
- Damascus University
Arthroplasty, Replacement, Knee
Outcome Study of Highly-cross Linked Polyethylene vs. Standard Polyethylene for Primary Posterior Stabilized (PS) Total Knee
Polyethylene wear and osteolysis remain a concern with the use of modular, fixed bearing total knee arthroplasty. A variety of highly cross-linked polyethylenes have been introduced to decrease this problem, but there is little…
- Trial name
- NCT02178020
- Testing
- knee arthroplasty, standard polyethylene, knee arthroplasty, XLP polyethylene
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Chapel Hill Orthopedics Surgery & Sports Medicine
Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication
Photobiomodulation and Root Resorption
Objectives: The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group. Materials and Methods: 30 patients, who were admitted to the ………….
- Conditions
- Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication, Orthodontic Tooth Movement
- Trial name
- NCT04044989
- Testing
- Laser, light-emitting diode (LED)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Bone Resorption
Using Platelet Rich Plasma in Reducing Alveolar Bone Resorption During Rapid Maxillary Expansion
The purpose of this study is to determine if the injection of Platelet-rich plasma (PRP) is effective in reducing alveolar bone loss that happens after each rapid maxillary expansion (RME) on the buccal aspect of the posterior…
- Trial name
- NCT03028038
- Testing
- Platelet Rich Plasma, No Platelet Rich Plasma
- Where
- Syria
- Volunteers
- 16 people
- Sponsor
- Damascus University
External Apical Root Resorption in Maxillary Canines During Orthodontic Retraction
Comparison of Root Resorption in Modified Corticotomy-Assisted and Conventional Canine Retraction
This randomized controlled clinical trial will compare external apical root resorption in patients undergoing maxillary canine retraction using modified corticotomy-assisted frictionless T-loop mechanics versus conventional…
- Trial name
- MCA-CR (NCT07458139)
- Testing
- Modified Corticotomy assisted frictionless canine retraction, Conventional Frictionless Canine retraction
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Pulpitis - Irreversible, Resorption, Root
The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars
The aim of the study is to perform a clinical and radiographic evaluation of 70% Ethanol Alcohol versus Normal Saline as root canal irrigating solutions in partial pulpectomy of primary molars with Metapex.
- Conditions
- Pulpitis - Irreversible, Resorption, Root, Abscess Bone, Mobility, Tooth
- Trial name
- NCT04669392
- Testing
- 70% Ethanol Alcohol
- Volunteers
- 20 people
- Sponsor
- Cairo University
Bone Resorption
Dietary Intake Modifications to Protect Against Changes in Bone Metabolism
Bone loss is not only a well-documented effect of spaceflight on astronauts, but also a condition that affects millions of men and women on Earth each year.
- Trial name
- ProK (NCT01713634)
- Testing
- Preflight, In-flight
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)
Root Resorption
Repair of Orthodontically-induced Tooth Root Resorption by Ultrasound
Tooth-root resorption, also known as shortening or erosion,(TRR) is one of the adverse outcomes of dental trauma, orthodontic tooth movement and dental replantation/transplantation.
- Trial name
- NCT00423956
- Testing
- Repairing Induced tooth root resorption by ultrasound
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Root Resorption
Amount of Root Resorption of Maxillary Anteriors After en Masse Versus Two Step Space Closure
The goal of this study is to compare the three dimensional root resorption after extraction space closure in two groups: two step retraction and en masse retraction.
- Trial name
- CBCT (NCT05606185)
- Testing
- retraction method
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Compare the Effect of Injectable Platelets Rich Fibrin and Micro-osteoperforations on Root Resorption During Orthodontic Intrusion of Incisors
Consequence of Injectable Platelets Rich Fibrin Versus Microosteopeforation on Root Resorption During Orthodontic Intrusion of Incisor Teeth
Consequence of injectable platelets rich fibrin versus microosteopeforation on root resorption during orthodontic intrusion of incisor teeth
- Trial name
- NCT05958498
- Testing
- injectable platelet rich fibrin and microosteoperforation
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Alveolar Bone Resorption, Alveolar Bone Grafting
Split Crest Procedure: Is It Necessary to Fill the Gap?
This prospective controlled clinical study evaluates the effectiveness of adding bone graft or dentin graft material during the split crest (alveolar ridge splitting) procedure for horizontal ridge augmentation with simultaneous…
- Conditions
- Alveolar Bone Resorption, Alveolar Bone Grafting, Bone Expansion
- Trial name
- NCT07272694
- Testing
- Split Crest Technique
- Where
- Serbia
- Volunteers
- 24 people
- Sponsor
- Vladimir Biocanin
Pneumoperitoneum
CO2 Absorption During Laparoscopy
CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia.
- Trial name
- NCT01340989
- Testing
- alteration of the insufflation gas, full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg