Clinical trials: Respiratory Functions
Obstructive Sleep Apnea, Down Syndrome (Trisomy 21)
Effects of a Pacifier on Obstructive Sleep Apnea and Its Repercussions in Infants With Down Syndrome
Obstructive Sleep Apnea (OSA) is characterised by repetitive collapse of the upper airway during sleep, inducing breathing disturbances that can result in oxygen desaturation and frequent arousals.
- Trial name
- TET21 (NCT07658053)
- Testing
- CURAPROX pacifier use, Pacifier diary, Polysomnography (PSG) to explore OSA
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Visual Impairment, Refractive and Accommodative Disorders
Babies in Glasses; a Feasibility Study.
This is a feasibility study to begin investigating the possibility that early use of near vision glasses will improve vision in infants at risk of Cerebral Visual Impairment (CVI), leading to further improvement in other areas of…
- Conditions
- Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy, Premature Birth
- Trial name
- BiG (NCT05048550)
- Testing
- Near vision spectacles
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Wheezing
Montelukast in Children With Wheezing
In this study children with recurrent wheezing (>/= 2 episodes in the last 6 months)and aged less than 2 years will be enrolled as outpatients.
- Trial name
- NCT00775697
- Testing
- Montelukast
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Universita di Verona
Asthma
Inflammatory, Functional and Image Composite Measure to Define Asthma Control
The goals of control status of asthma have been changed with the improvement of its management as a chronic disease; many steps should be taken to achieve asthma control as defined by the GINA/NIH guidelines.
- Trial name
- APITA (NCT00597064)
- Testing
- prednisone
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of São Paulo
Respiratory Function Tests
Exercise Induced Asthma and Airway Reactivity in Athletes
The overall aim is to explore pathophysiological factors related to airway hyperresponsiveness to direct and indirect provocation stimuli in athletes with different sport activities, with special focus on epithelial reaction…
- Trial name
- NCT00798564
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Cerebral Palsy, Respiratory Function
Inspiratory Muscle Training in Children With Cerebral Palsy: Effects on Respiratory and Motor Functions
This study investigates the effect of inspiratory muscle training on respiratory parameters, trunk control, upper extremity function and swallowing in patients with cerebral palsy aged 5-18 years.
- Conditions
- Cerebral Palsy, Respiratory Function, Balance, Swallowing
- Trial name
- NCT07041593
- Testing
- Inspiratory muscle training and standard neurodevelopmental physiotherapy (SNP), Standard neurodevelopmental physiotherapy (SNP)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Sadık Emre ÇELEBİ
Burns, Respiratory Function Impaired
Inspiratory Muscle Training in Children With Chest Burn
8 weeks of inspiratory muscle training combined with a pulmonary rehabilitation program increases respiratory muscle strength, pulmonary function, functional capacity, and quality of life in chest burned children.
- Conditions
- Burns, Respiratory Function Impaired, Children
- Trial name
- chestburn (NCT05603507)
- Testing
- inspiratory muscle training, pulmonary rehabilitation
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Qassim University
Hematopoietic Stem Cell Transplantation
Effectiveness Rehabilitation Hematopoietic Transplantation (ovERsHOT)
The objective of the study is to evaluate the benefits and costs of a comprehensive rehabilitation program (physical, psychological, social and educational) for patients receiving hematopoietic stem cell transplantation (HSCT).
- Trial name
- ovERsHOT (NCT03324620)
- Testing
- Specific program functional and respiratory rehabilitation
- Where
- Spain
- Volunteers
- 190 people
- Sponsor
- Hospital Clinic of Barcelona
Chronic Lung Disease, Chronic Obstructive Pulmonary Disease
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with…
- Conditions
- Chronic Lung Disease, Chronic Obstructive Pulmonary Disease, Acute Lymphoblastic Leukemia, Heart Transplant
- Trial name
- FLASHLITE (NCT05025774)
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Cystic Fibrosis, Muscle Strength
Muscle Strength, Functional Capacity, Respiratory Function and Quality Of Life In Cystic Fibrosis Patients
This study was designed to investigate the relationship between upper extremity muscle strength and endurance, functional capacity, and quality of life child and adolescent with cystic fibrosis
- Conditions
- Cystic Fibrosis, Muscle Strength, Pulmonary Function, Functional Capacity
- Trial name
- NCT04734743
- Testing
- cystic fibrosis
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cagtay Maden
Lower Urinary Tract Disorder
Pelvic Floor Muscle Activity, Respiratory Functions, Respiratory Muscle Strength, and Functional Capacity in Children With Lower Urinary Tract Dysfunction
The functional disorders of the lower urinary tract in children involve overactive bladder with thickening of the bladder muscle, resulting in a decrease in functional bladder volume and an increase in intra-bladder pressure.
- Trial name
- NCT06652178
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cystic Fibrosis, Cystic Fibrosis in Children
Effect of Parental Attitude on Functional and Physical Level of Children With Cystic Fibrosis
Some parents may be more protective of children with CF due to concerns about worsening of the disease due to infection, which can affect their functional level.
- Trial name
- NCT06306508
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Halic University
Spinal Muscular Atrophy
Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen Treatments
It is well known that patients with spinal muscular atrophy (SMA) have progressive decline of respiratory muscle function. Therapy traditionally involved supportive means to ensure optimal nutrition and airway clearance.
- Trial name
- NCT04050852
- Testing
- Nusinersen Treatments
- Where
- United States
- Sponsor
- NYU Langone Health
Wheezing
Nebulized Beclomethasone Dipropionate Improves Respiratory Lung Function in Preschool Children With Recurrent Wheezing
This is a single-centre, open label study, aiming to evaluate the efficacy of beclomethasone dipropionate applied for 12 weeks with a dose of 400 µg twice a day (total dose 800 µg nebulized), on airway resistance and reactances…
- Trial name
- NCT02381158
- Testing
- Nebulized beclomethasone dipropionate
- Volunteers
- 12 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Asthma
The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Asthma is a common inflammatory airway disease. Several researches have demonstrated a possible connection between asthma and exposure to paracetamol.
- Trial name
- NCT01073748
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Adolescent Idiopathic Scoliosis (AIS), Scoliosis; Adolescence
Effects of Expiratory Muscle Strength Training in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis result in deterioration of core muscles and respiratory system. Core muscles provide trunk stabilization as well as responsible for respiratory system. Especially tr.
- Trial name
- NCT06752993
- Testing
- Expiratory Muscle Strength Training (EMST-150)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University
Obstructive Sleep Apnea, Balance
Functional Assessment and Sleep Apnea in Obese Children and Adolescents
Childhood obesity increases significantly, and determines several complications in childhood and adulthood, and the worldwide prevalence of childhood obesity has shown a rapid increase in recent decades.
- Conditions
- Obstructive Sleep Apnea, Balance, Obesity, Childhood
- Trial name
- NCT05563311
- Testing
- Exercise on High-intensity interval training
- Where
- Brazil
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Cystic Fibrosis
Interest of Gentamicin-induced Readthrough in Cystic Fibrosis Patients
Suppression of stop mutations in the CFTR gene with parenteral gentamicin can be predicted in vitro and is associated with clinical benefit and significant modification of the CFTR-mediated chloride transport in nasal and sweat…
- Trial name
- NCT00376428
- Testing
- Gentamicin
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho