Clinical trials: Resuscitations
Out-Of-Hospital Cardiac Arrest
International Termination of Resuscitation Practices
Neither the international nor the interregional variation in survival following OHCA is fully understood, but may rely on multiple factors such as: organization of the Emergency Medical Service (EMS) system bystander…
- Trial name
- NCT05029180
- Testing
- Termination of resuscitation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Airway Aspiration, Cardiopulmonary Arrest
The Impact of Soiled Airway Management on CPR Quality
Regurgitation is an adverse event common during cardiopulmonary resuscitation (CPR) and occurs in 20%-32% of patients experiencing out-of-hospital cardiac arrest (OHCA).
- Trial name
- NCT05278923
- Testing
- SALAD simulation device
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation, Out of Hospital Cardiac Arrest
RESTORE-ZG: Return of Effective Spontaneous Circulation Resuscitation Evaluation Canton of Zug
This study looked at cardiac arrest that happens outside a hospital. Cardiac arrest means the heart suddenly stops pumping blood. When this happens, a person collapses and needs help right away.
- Conditions
- Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation, Out of Hospital Cardiac Arrest, Out of Hospital Setting, Defibrillation
- Trial name
- RESTORE-ZG (NCT07750119)
- Testing
- Prehospital resuscitation care
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Felix Brinkmann
Cardiopulmonary Resuscitation
Optimization of Quality in Cardiopulmonary Resuscitation Through Monitor-defibrillator With Feedback System
AIM: To verify the effect of a feedback system on optimizing quality during CPR on mannequins. Hypothesis: The quality of CPR performed by healthcare professionals through a defibrillator monitor with a feedback system is higher…
- Trial name
- NCT04357548
- Testing
- FEEDBACK
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Neonatal Resuscitation, Infant, Premature
Heart Rate Evaluation and Resuscitation Trial in Preterm Neonates
The purpose of this study is to determine whether using electrocardiograms (ECGs) during resuscitation of preterm infants (less than 31 weeks gestation) will decrease the amount of time it takes from birth for heart rate (HR) to…
- Trial name
- HEART (NCT03133663)
- Testing
- Electrocardiogram group, Pulse oximeter and auscultation group
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Texas Southwestern Medical Center
Premature Birth
HeartLight Pulse Study: Evaluation of Heart Rate Using an Electronic Stethoscope and Pre Placed ECG in the Delivery Room
This study will evaluate the accuracy of both an electronic stethoscope and electrocardiogram (ECG) to evaluate heart rate in neonatal patients in the delivery suite.
- Trial name
- HLPulseS (NCT02747069)
- Testing
- NICU electronic stethoscope, Newborns <32 weeks and ECG
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Septic Shock
Fluid Resuscitation for Suspected Sepsis in Paediatric Emergency Departments
With 25.2 million children affected and 3.4 million deaths in 2017, paediatric sepsis is the leading cause of under-five mortality worldwide and has recently been described as "significant global health threat" by the World…
- Trial name
- FRESSPED (NCT05066464)
- Testing
- Fluid Resuscitation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sepsis
Early Resuscitation in Paediatric Sepsis Using Inotropes
Septic shock in children still carries substantial mortality and morbidity. While resuscitation with 40-60 mL/kg intravenous fluid boluses remains a cornerstone of initial resuscitation, an increasing body of evidence indicates…
- Trial name
- ANDES-CHILD (NCT06478797)
- Testing
- Fluid, Adrenalin
- Where
- 4 sites in Argentina, Bolivia and 1 more
- Volunteers
- 40 people
- Sponsor
- NATALIA LOPERA MUNERA
Infant, Newborn, Diseases, Fetus or Neonate Affected by Cesarean Section
HeartLight: Heart Rate Monitoring for Newborn Resuscitation
This study will compare a newborn heart rate sensor (HeartLight) that is integrated into a hat with other common forms of heart rate monitoring such as electrocardiography (ECG), stethoscope and pulse oximetry (PO) in newborn…
- Conditions
- Infant, Newborn, Diseases, Fetus or Neonate Affected by Cesarean Section, Infant, Premature, Diseases
- Trial name
- HeartLight (NCT02701920)
- Testing
- HeartLight hat, The HeartLight hat with in-built sensor, HeartLight
- Where
- United Kingdom
- Volunteers
- 184 people
- Sponsor
- University of Nottingham
Fetal Distress
Effect of Umbilical Cord Milking on Transition of Preterm Babies During Resuscitation
Investigators will evaluate if milking of umbilical cord in preterm babies will improve transition during resuscitation or not
- Trial name
- NCT03859037
- Testing
- Umbilical cord milking
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Stillbirth, Neonatal Respiratory Depression
Newborn Heart Rate as a Catalyst for Improved Survival
Heart rate (HR) is not routinely assessed during newborn resuscitations in low- and lower-middle income countries (LMICs). Many non-breathing newborns classified as fresh stillbirths have a heartbeat and are live born.
- Conditions
- Stillbirth, Neonatal Respiratory Depression, Neonatal Bradycardia, Neonatal Resuscitation
- Trial name
- NCT03799861
- Testing
- Epoch 2: HBB with NeoBeat, Epoch 3: HR-guided HBB
- Where
- 3 sites in Democratic Republic of the Congo
- Volunteers
- 24,034 people, healthy volunteers welcome
- Sponsor
- American Academy of Pediatrics
Birth Asphyxia
Umbilical Cord Milking in Non-Vigorous Infants
The investigators will conduct a study of non-vigorous term infants to determine if umbilical cord milking (UCM) results in a lower rate of NICU admissions than early clamping and cutting of the umbilical cord at birth for…
- Trial name
- MINVI (NCT03631940)
- Testing
- Umbilical Cord Milking, Early Cord Clamping
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 1,730 people
- Sponsor
- Sharp HealthCare
Cardiac Arrest
Prospective Assessment Project About Cardiac Arrest Resuscitation
In case of a cardiac arrest it is very important to quickly provide high quality cardiopulmonary resuscitation (CPR). For reasons of patient safety the investigators want to assess the frequency, the quality and the outcome of…
- Trial name
- NCT02746640
- Testing
- Cardiopulmonary resuscitation (CPR)
- Where
- Switzerland
- Volunteers
- 148 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Simulated Pediatric CRP Ventilation
Simulation-based Comparative Study on Efficiency of Ventilation During Paediatric Cardiopulmonary Resuscitation
The aim of this study is to gather data to support beginning the pediatric cardiopulmonary resuscitation (CPR) with 5 initial breaths.
- Trial name
- PEDIVENT (NCT05345704)
- Testing
- cardiopulmonary resuscitation (CPR)
- Where
- Czechia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation
Cross-sectional Survey of Zhejiang ECMO Application
Extracorporeal lung oxygenation (ECMO) was first used in neonates in the 1970s and is now widely used to treat adult patients with intractable shock and respiratory failure who have failed various types of conventional life…
- Conditions
- Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation, Epidemiology
- Trial name
- NCT04979325
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Preterm Birth
Use of CO2 Detectors to Help Provide Effective Breaths During Resuscitation of Preterm Newborns
Effective ventilation is the single most vital intervention to improve outcome of resuscitation in the neonatal population. Assessments of effective ventilations are based on clinical parameters, but may be difficult due to…
- Trial name
- NCT04287907
- Testing
- Monitor Group
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Congenital Diaphragmatic Hernia
Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord
Congenital diaphragmatic hernia (CDH) is a severe birth defect, with a prevalence of 1:2000 to 1:3000 live births where a defect in the diaphragm results in, herniation of the abdominal contents into the chest with subsequent…
- Trial name
- NCT03242044
- Testing
- Congenital diaphragmatic hernia resuscitation with an intact umbilical cord
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Out-of-Hospital Cardiac Arrest
Induced Hypothermia in Cardiac Arrest Patients Rescued by Extracorporeal Cardiopulmonary Resuscitation.
Background： Cardiopulmonary resuscitation (CPR) with closed-chest cardiac massage has been shown that survival to discharge rate is poor.
- Trial name
- NCT00965016
- Testing
- hypothermia
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Min-Sheng General Hospital
Cardiopulmonary Resuscitation
How is the Term 'Harm' Being Interpreted and Documented on Hospice DNACPR Forms Following the Tracey Judgement?
To investigate how discussions surrounding Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) decisions have changed following the Tracey judgement and how "harm" is being defined by clinicians working within specialist…
- Trial name
- NCT03195725
- Testing
- Review of notes
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Cardiac Arrest
Effect of Pre-imaging on Cardiopulmonary Resuscitation (CPR) Pause
Patients presenting following out of hospital cardiac arrest will undergo bedside ultrasound as per the hospital clinical practice.
- Trial name
- NCT04248985
- Testing
- Pre-Imaging - an ultrasound technique of acquiring images
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Massachusetts, Worcester