Clinical trials: Retreatment
Crohn Disease
The Intensive Post Exclusive Enteral Nutrition Study
Crohn's disease (CD) is a chronic inflammatory condition with phases where the disease is active and other, where there are no symptoms.
- Trial name
- iPENS (NCT04225689)
- Testing
- CD-TREAT diet
- Where
- 5 sites in United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Root Canal Infection, Periapical; Infection
Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques
Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.It has been stated that the one of the main cause of posttreatment…
- Trial name
- NCT03750162
- Testing
- VDW Ultra, AMD picasso, ProtaperNext X3 gutta-percha
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Smoking Cessation
Varenicline (Champix®) Special Investigation (Regulatory Post Marketing Commitment Plan)
The purpose of this study is to collect the efficacy and safety information in subjects who have been retreated with varenicline (Champix®) within 52 weeks of initial treatment for their appropriate use in daily practice and are…
- Trial name
- NCT01061710
- Testing
- varenicline
- Volunteers
- 20 people
- Sponsor
- Pfizer
Root Canal Infection
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant
This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.
- Trial name
- NCT04250519
- Testing
- Sodium Hypochlorite
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Endodontically Treated Teeth, Endodontical Retreatment
Broken Instrument Removal
The aims of this retrospective analysis are (1) to evaluate the success rate of a non-surgical retreatment of teeth with broken file instrument into the canal using ultrasounds, microscope and a modified spinal needle, (2) to…
- Trial name
- NCT05128266
- Testing
- Endodontical Retreatment
- Volunteers
- 161 people
- Sponsor
- Catholic University of the Sacred Heart
Postoperative Pain, Flare Up, Symptom
Effect of a Herbal Intracanal Medication On Postoperative Pain And Flare up Incidence In Non Surgical Root Canal Retreatment
The primary objective of this randomized clinical trial is to evaluate and compare the effectiveness of two natural, herbal-based intracanal medications-Propolis and Green Tea Polyphenolics (EGCG)-against the conventional Calcium…
- Conditions
- Postoperative Pain, Flare Up, Symptom, Flare up
- Trial name
- NCT07578311
- Testing
- Calcium hydroxide, Propolis Extract, Green Tea Polyphenolics (EGCG)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Plaque Psoriasis
A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis
The purpose of this study is see how effective is JNJ-77242113 in participants with moderate to severe plaque psoriasis.
- Trial name
- ICONIC-LEAD (NCT06095115)
- Testing
- JNJ-77242113
- Where
- 170 sites in United States, Argentina and 14 more
- Volunteers
- 684 people
- Sponsor
- Janssen Research & Development, LLC
Hypersensitivity, Beta Lactam Adverse Reaction
Protocol of Reintroduction of Beta-lactams in Children at Low Risk of Anaphylaxis.
The purpose of this study is to establish the rationale for the practice of performing an oral reintroduction test without previous skin tests in children at low risk of IgE-mediated reaction or drug-induced toxidermia, and to…
- Trial name
- TRO-b-lact (NCT03553251)
- Where
- France
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Apical Periodontitis
Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment
Post-treatment apical periodontitis is commonly associated with persistent intracanal infection following root canal treatment. Effective disinfection of the complex root canal system during nonsurgical retreatment remains…
- Trial name
- NCT07469150
- Testing
- GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Endodontic Disease
Postoperative Pain and Incidence of Extrusion Following the Use of Two Intra-canal Medications in Retreatment of Single Rooted Teeth
This study aims to compare the postoperative pain and incidence of extrusion of two intracanal medications in the retreatment of single-rooted teeth.
- Trial name
- NCT06913673
- Testing
- Bio-c Temp, Metapex
- Volunteers
- 30 people
- Sponsor
- Minia University
Chronic Spontaneous Urticaria
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab
The purpose of this extension study was to establish efficacy and safety of ligelizumab. This was assessed in adult and adolescent chronic spontaneous urticaria (CSU) patients who had completed a preceding ligelizumab study and…
- Trial name
- NCT04210843
- Testing
- Ligelizumab
- Where
- 273 sites in United States, Argentina and 43 more
- Volunteers
- 1,033 people
- Sponsor
- Novartis Pharmaceuticals
Diabetic Macular Edema
Intravitreal Dexamethasone Implant for Refractory Diabetic Macular Edema:
We have been using DEX for refractory DME for a long time (since 2016). Thus, we are sharing our results , evaluating both anatomical and functional outcomes of DEX therapy for refractory DME.
- Trial name
- NCT05847088
- Testing
- Intravitreal Dexamethasone Implant for refractory Diabetic macular edema:
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Dar El Oyoun Hospital
Tuberculosis, Pulmonary
Novel Triple-dose Tuberculosis Retreatment Regimens: How to Overcome Resistance Without Creating More
Drug-resistance is a major challenge for tuberculosis (TB) care programs. The new WHO guideline recommends adding levofloxacin in previously treated patients with isoniazid-resistant rifampicin-susceptible TB.
- Trial name
- TriDoRe (NCT03862248)
- Testing
- 6EH³RZ, 6EHR³Z, 6EHRZLfx
- Where
- Bangladesh
- Sponsor
- Institute of Tropical Medicine, Belgium
Kawasaki Disease
A Trial Comparing the Efficacy and Safety of Anakinra Versus Intravenous Immunoglobulin (IVIG) Retreatment, in Patients With Kawasaki Disease Who Failed to Respond to Initial Standard IVIG Treatment
Kawasaki disease (KD) is the most frequent vasculitis in younger children <5years, and the first cause of acquired ischemic myocardiopathy in childhood.
- Trial name
- ANACOMP (NCT04656184)
- Testing
- ANAKINRA, Intravenous immunoglobulin
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Drug Induced Hepatotoxicity, Tuberculosis
Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage
Purpose of the study is to evaluate the safety and efficacy of different re-introduction regimens in anti-TB drug induced liver damage. There is no consensus how best to treat such patients who developed drug induced liver damage.
- Trial name
- NCT00405301
- Testing
- Rifampicin(max dose 10 mg/kg/day), Isoniazide (max dose 5 mg/kg/day) and Pyrazinamide (max dose 25 mg/kg/day)
- Where
- 2 sites in India
- Volunteers
- 175 people
- Sponsor
- All India Institute of Medical Sciences
Lupus Nephritis
A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Lupus Nephritis Previously Enrolled in Study U2970g
This is a Phase III, multicenter, extension study to evaluate the safety of rituximab administered on a scheduled basis approximately every 6 months.
- Trial name
- NCT00404157
- Testing
- Rituximab
- Sponsor
- Genentech, Inc.
Endodontic Retreatment, Non-surgical Retreatment
Development and Validation of a Deep Learning Model to Predict Endodontic Retreatment Difficulty From Periapical Radiographs
The aim of this study is to develop and evaluate an artificial intelligence-based model capable of analyzing periapical radiographs of maxillary and mandibular molars to predict the difficulty level of non-surgical root canal…
- Conditions
- Endodontic Retreatment, Non-surgical Retreatment, Endodontics, AI (Artificial Intelligence)
- Trial name
- Ai Retreatment (NCT07611279)
- Testing
- Deep Learning Model to Predict Endodontic Retreatment Difficulty from Periapical Radiographs
- Volunteers
- 123 people
- Sponsor
- Cairo University
Revascularization
Evaluation of Retreatment of Failed Revasculatized Teeth by Revascularization
Study will include 30 participants with failed revascularized young permenant teeth that will be retreated by revascularization and evaluated for success through 2 years
- Trial name
- NCT05147025
- Testing
- Revascularization
- Volunteers
- 60 people
- Sponsor
- Minia University
Food Allergies
Master Allergen Child Nutrition. Reintroduction of Small Doses
Reintroduction of small doses of food in allergic children to lightening the elimination diet.
- Trial name
- MANOE (NCT02384707)
- Testing
- allegic food
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers