Clinical trials: Retreatment
This Study Compares the Effects of Two Working Length Methods on Postoperative Pain in Single-rooted, Single-canal Teeth During Root Canal Retreatment
Evaluation of Postoperative Pain After Endodontic Retreatment Using Different Working Length Determination Methods: A Randomized Clinical Trial
The aim of this study is to compare the effects of two different working length determination methods on the incidence of postoperative pain in single-rooted, single-canal teeth undergoing root canal retreatment (RCR).
- Trial name
- NCT06732063
- Testing
- endodontic retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- öznur dişli
Apical Periodontitis, Retreatment
Biomarkers in Apical Periodontitis
Aim: To evaluate the effects of three different irrigation activation techniques-conventional syringe irrigation (CSI), ultrasonic irrigation (UI), and SWEEPS (Shock Wave Enhanced Emission Photoacoustic Streaming)-on the levels…
- Conditions
- Apical Periodontitis, Retreatment, Biomarkers, Cytokine
- Trial name
- NCT07504861
- Testing
- laser activation, PUI, CSI
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Postoperative Pain, Medicaments Substances in Therapeutic Use
Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients Undergoing Endodontic Treatment: a Clinical Study
This clinical study is designed to evaluate postoperative pain experienced by patients undergoing multi-visit endodontic retreatment and to investigate whether the choice of intracanal medicament influences pain levels between…
- Conditions
- Postoperative Pain, Medicaments Substances in Therapeutic Use, Calcium Hydroxide, Root Canal Retreatment
- Trial name
- NCT07396688
- Testing
- bioceramic based intracanal medication, Calcium Hydroxide Intracanal medication
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara University
Retreatment, Asymptomatic Apical Periodontitis
Effects of Irrigation Activation Systems on Postoperative Pain and Lesion Healing in Single-Visit Retreatment
In this superiority randomized clinical trial with a parallel design, 75 asymptomatic maxillary anterior teeth with 2-5 mm periapical lesions and a history of primary root canal treatment (PRCT) at least four years earlier were…
- Trial name
- NCT07150585
- Testing
- Ultrasonic Activation Group, Sonic Activation Group, Laser Activation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ege University
Non-surgical Retreatment
Effects of Different NiTi Systems on Postoperative Pain and Operation Time in Nonsurgical Endodontic Retreatment
This prospective, randomized, single-center, single-blind clinical trial evaluated the effects of different nickel-titanium retreatment and final shaping systems on postoperative pain and operation time during single-visit…
- Trial name
- NiTi-RETREAT (NCT07783945)
- Testing
- ProTaper Universal Retreatment System, MicroMega REMOVER, ProTaper Next
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Asymptomatic Apical Periodontitis, Root Canal Retreatment
Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer
The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in…
- Trial name
- NCT06973135
- Testing
- Bioceramic sealer root canal obturation, resin sealer root canal obturation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Saly Nazeer
Asymptomatic Apical Periodontitis, Endodontic Retreatment
Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment
This prospective, randomized, controlled, single-blind, parallel-group clinical trial evaluates whether intracanal cryotherapy reduces postoperative pain and inflammatory biomarker levels following single-visit endodontic…
- Conditions
- Asymptomatic Apical Periodontitis, Endodontic Retreatment, Cryotherapy
- Trial name
- ICE-PAIN (NCT07733700)
- Testing
- Intracanal cryotherapy, Room-temperature saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Alanya Alaaddin Keykubat University
Endodontics, Regenerative Endodontic Procedures
The Effect of Using Different Scaffolds in Retreated Teeth on The Clinical and Radiological Success of Regenerative Endodontic Treatment
This clinical study aims to compare the clinical and radiographic outcomes of four different scaffolds used in regenerative endodontic treatment of previously root canal-treated permanent teeth requiring retreatment.
- Conditions
- Endodontics, Regenerative Endodontic Procedures, PRF, i-PRF
- Trial name
- NCT07721051
- Volunteers
- 60 people
- Sponsor
- Kırıkkale University
Intervention Studies, ASA Physical Status I
Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases
The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3.
- Conditions
- Intervention Studies, ASA Physical Status I, Intracanal Medication, Periapical Abscess
- Trial name
- RCT (NCT07641933)
- Testing
- Calcium Silicate Intracanal Medication, Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Endodontic Retreatment, Non-surgical Retreatment
Development and Validation of a Deep Learning Model to Predict Endodontic Retreatment Difficulty From Periapical Radiographs
The aim of this study is to develop and evaluate an artificial intelligence-based model capable of analyzing periapical radiographs of maxillary and mandibular molars to predict the difficulty level of non-surgical root canal…
- Conditions
- Endodontic Retreatment, Non-surgical Retreatment, Endodontics, AI (Artificial Intelligence)
- Trial name
- Ai Retreatment (NCT07611279)
- Testing
- Deep Learning Model to Predict Endodontic Retreatment Difficulty from Periapical Radiographs
- Volunteers
- 123 people
- Sponsor
- Cairo University
Apical Periodontitis, Postoperative Pain
Effect of Integrated Apex Locator Motor Modes on Postoperative Pain in Endodontic Retreatment
This randomized controlled clinical trial aimed to evaluate the effect of different integrated electronic apex locator (EAL) modes on postoperative pain following nonsurgical endodontic retreatment.
- Conditions
- Apical Periodontitis, Postoperative Pain, Endodontic Retreatment
- Trial name
- EAL-Pain (NCT07527897)
- Testing
- Electronic Apex Locator, Integrated Apex Locator Motor
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Recep Tayyip Erdogan University
This Study Will be Performed to Evaluate the Efficiency of 810 nm Diode Laser Disinfection on Periapical Healing in Root Canal Retreatment Cases
The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment
The main cause of endodontic disorders is microbial infection. From the infected root canal, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and…
- Trial name
- Retreatment (NCT07194837)
- Testing
- diode laser, Calcium Hydroxide (Ca(OH)2)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Root Canal Therapy, Root Canal Retreatment
Factors Affecting Success and Survival Rates in Root Canal Retreatment
The aim of this study is to evaluate the effects of pre-treatment and procedural factors on survival and success rates in teeth that underwent non-surgical root canal retreatment at Trakya University, Faculty of Dentistry between…
- Trial name
- NCT07005492
- Testing
- radiological and clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Trakya University
Retreatment
Effect of Different Apex Locators on Postoperative Pain in Endodontic Retreatment of Single-Rooted Teeth: Prospective Randomized Clinical Study
Nonsurgical endodontic retreatment is a vital procedure that promotes periapical healing by eliminating previous root canal fillings, necrotic tissue, and residual microorganisms, thanks to the comprehensive cleaning of the root…
- Trial name
- NCT06964490
- Testing
- determination of working length
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ipek Eraslan Akyuz
Retreatment, Cryotherapy
Effect of Intracanal Cryotherapy on Postoperative Pain
Introduction: Since 1960, cryotherapy, involving the application of cold, has been used in various fields of medicine for pain treatment.
- Trial name
- NCT06764823
- Testing
- Cryotherapy, Control
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Gastric Cancer, Gastroesophageal Junction Cancer, Immune Checkpoint Inhibitors (ICIs)
Immune Checkpoint Inhibitors (ICIs) Retreatment in Second-line Treatment of Advanced Gastric Cancer: a Retrospective, Real-world Study
This is a single-center, retrospective, observational, real-world study. We collected general and clinical data of patients with advanced gastric cancer who were admitted to the First Affiliated Hospital of Zhengzhou University…
- Conditions
- Gastric Cancer, Gastroesophageal Junction Cancer, Immune Checkpoint Inhibitors (ICIs), Second-line, Retreatment
- Trial name
- NCT06814548
- Testing
- ICIs(Immune checkpoint inhibitors)
- Volunteers
- 200 people
- Sponsor
- Yongxu Jia
Retreatment
Post Operative Pain After Endodontic Retreatment
Clinical Trial The aim of this clinical study was to evaluate the effect of different root canal sealers on post operative pain after a single session endodontic retreatment of the teeth have single root and canal with chronic…
- Trial name
- NCT06803277
- Testing
- endodontic retreatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Post-operative Pain, Retreatment
Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic Teeth
Introduction: The aim of this study comparing the post operative pain after the retreatment of asymptomatic and symptomatic teeth that during single visit treatment with rotary and reciprocal nickel titanium files.
- Conditions
- Post-operative Pain, Retreatment, Symptomatic Periapical Periodontitis, Endodontic Disease
- Trial name
- Endodontics (NCT06357481)
- Testing
- Endodontic Retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
PARP Inhibitor Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment
Oregovomab and PLD in PARP Inhibitor Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment
This study is phase II, open label, clinical trial to determine the efficacy of Oregovomab and non-platinum chemotherapy in PARP inhibitor resistant ovarian, fallopian tube, or primary peritoneal cancer patients who were not…
- Trial name
- NCT05407584
- Testing
- Orevogomab+PLD, Orevogomab+Paclitaxel
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Endodontically Treated Teeth, Endodontical Retreatment
Broken Instrument Removal
The aims of this retrospective analysis are (1) to evaluate the success rate of a non-surgical retreatment of teeth with broken file instrument into the canal using ultrasounds, microscope and a modified spinal needle, (2) to…
- Trial name
- NCT05128266
- Testing
- Endodontical Retreatment
- Volunteers
- 161 people
- Sponsor
- Catholic University of the Sacred Heart