Clinical trials: Root Canal Treatment
Dental Pulp Diseases, Dental Pulp Necrosis
Non-instrumentation Root Canal Treatment of Primary Molars
This randomized clinical trial intended to evaluate the efficacy of a technique of root canal treatment of deciduous molars with non-instrumentation of root canals and use of a paste containing antibiotics (chloramphenicol and…
- Trial name
- EndoDecide-1 (NCT04942158)
- Testing
- Non-instrumentation technique with use of CTZ paste, Instrumentation technique and filling with Zinc Oxide and Eugenol paste
- Where
- 4 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- University of Sao Paulo
Bronchial Asthma
Salbutamol Administration by Nebulizer Versus Metered Dose Inhaler With Spacer in Asthma in Children
Asthma is a problem that affects many children and affects their physical health in addition to having a social and financial burden on individuals, families and healthcare systems.
- Trial name
- NCT03816267
- Testing
- Nebulizer, Salbutamol, Metered dose inhaler and spacer
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Apexification, Apexogenesis
Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma
Children often damage their front teeth. In approximately 6% of cases, the nerve inside the affected tooth dies (becomes 'non-vital') and natural root development stops.
- Conditions
- Apexification, Apexogenesis, Pulp Necrosis, MTA
- Trial name
- NCT01817413
- Testing
- Mineral trioxide aggregate, Revascularisation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Liverpool
Apical Periodontitis
Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment
Post-treatment apical periodontitis is commonly associated with persistent intracanal infection following root canal treatment. Effective disinfection of the complex root canal system during nonsurgical retreatment remains…
- Trial name
- NCT07469150
- Testing
- GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Root Canal Disinfection
Estimate the Effect of aPDT on Root Canal Disinfection
The aim of this study is to compare the clinical effect of traditional root canal disinfection and aPDT on root canal disinfection. And provide the reference for clinical application and experience.
- Trial name
- NCT02929927
- Testing
- Rubber dam isolation, aPDT, 1% iodine tincture
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Postoperative Complication, Root Canal Therapy
Comparison of Endodontic Flare up in Single Visit Root Canal Treatment Versus Multiple Visit Root Canal Treatment in Patients Visiting Scd, Swat.
This randomized controlled trial aims to compare the incidence of endodontic flare-ups in patients undergoing single-visit versus multiple-visit root canal treatment (RCT) at Saidu College of Dentistry, Swat.
- Conditions
- Postoperative Complication, Root Canal Therapy, Pulpitis - Irreversible
- Trial name
- NCT06972433
- Testing
- single visit root canal treatment, Multiple visit root canal treatment
- Volunteers
- 344 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Dental Pulp Necrosis
Root Canal Treatment in Primary Molars With Necrotic Pulp Using Two Different Pulp Therapies
This is a controlled, randomized, double-blind clinical study (researcher and research participant does not know which group they belong to), with the objective of evaluating clinical and radiographic performances of primary…
- Trial name
- NCT03650036
- Testing
- Pulp Therapy CTZ Paste, Pulp Therapy ZOE Paste
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- Federal University of Piaui
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Dentinal Loss
Guided Endodontics Compared to Conventional Endodontic Treatment in Calcified Lower Incisors
The dental pulp is a vital tissue that can be prone to physiological or pathological changes. Denticles, pulp stones, or other calcifications are frequently observed within "healthy" pulps.
- Trial name
- NCT06484218
- Testing
- conventional endodontic treatment, Guided endodontic treatment
- Where
- Lebanon
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Irreversible Pulpitis (toothache)
Garlic Oil As Root Filling Material in Primary Molars
The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years.
- Trial name
- NCT06755502
- Testing
- Garlic oil, Calcium Hydroxide, Iodoform, paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ultrasound Therapy; Complications
Ultrasound-Guided Versus Conventional Method for Caudal Block
Caudal epidural block has been widely used, especially in pediatric surgery, to supply intraoperative and postoperative analgesia by affecting the region between T10 and S5 dermatomes in surgeries below the umbilical level.
- Trial name
- NCT03427437
- Testing
- Bupivacaine, Adrenalin, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Omer Karaca
Lumbar Disc Herniation
Comparative Study Between UBE and PETD for the Treatment of Lumbar Spinal Canal Stenosis
OBJECTIVE Both unilateral biportal endoscopy technique(UBE) and percutaneous endoscopic transforaminal discectomy(PETD) are minimally invasive and effective surgical procedures for lumbar spinal stenosis.The object of this…
- Trial name
- NCT05033457
- Testing
- unilateral biportal endoscopy technique or percutaneous endoscopic transforaminal discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shaanxi Provincial People's Hospital
Pulpitis - Irreversible
Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment
Pulpotomy has been proposed in the last decade as a definitive treatment of mature permanent teeth with irreversible pulpitis due to the better understanding of the pulp biology and development of bioactive materials .
- Trial name
- NCT03916900
- Testing
- Pulpotomy, Root canal treatment
- Volunteers
- 52 people
- Sponsor
- Cairo University
Apical Periodontitis, Root Canal Infection
Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal
The aim of the study is first, to evaluate the clinical antibacterial efficacy of two different NaOCl concentrations (2,5% and 5%) under a predefined irrigant flow rate in teeth with pulp necrosis and apical periodontitis by…
- Trial name
- ENDOA (NCT06949176)
- Testing
- Root canal tratment using mecchanical and chemical preparation., Sodium Hypochlorite., Hydrogen peroxide.
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Root Canal Treatment in Children Primary Molars, Postoperative Pain
Efficiency of Sonic Activation During Root Canal Treatment of Primary Molars on Postoperative Pain and Facial Expressions
This study was conducted to evaluate the efficiency of sonic activation of 5%sodium hypochlorite during root canal treatment of primary molars on postoperative pain and facial expressions.
- Conditions
- Root Canal Treatment in Children Primary Molars, Postoperative Pain, Facial Expressions, Facial Emotions
- Trial name
- NCT07138937
- Testing
- Root canal treatment in primary molars with irreversible pulpitis, EDDY system for sonic activation of irrigation, side-vented needle
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Intracanal Medicament
Comparison of Inter-appointment Pain Reduction During Root Canal Treatment in Symptomatic Apical Periodontitis by Using Intracanal Medicaments; Chlorhexidine Gel and Single Antibiotic Paste Nitrofurantoin
This study is being conducted to find out which of two medications-Chlorhexidine Gel or Nitrofurantoin-works better in reducing pain between root canal treatment visits.
- Trial name
- NCT07198919
- Testing
- Chlorhexidine gel, Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Altamash Institute of Dental Medicine
Irreversible Pulpitis (Toothache), Dental Caries (Diagnosis)
Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis
The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first…
- Trial name
- NCT07046533
- Testing
- (pulpotomy), root canal treatment
- Volunteers
- 60 people
- Sponsor
- Lamiaa Saeed Ahmed Elshiekh
Apical Periodontitis
Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Study aimed at assessing the clinical and radiographic success of pulp regeneration using injectable platelet-rich fibrin in mature permanent molars with apical periodontitis versus root canal treatment using Gutta Percha (GP)…
- Trial name
- NCT06086249
- Testing
- Regeneration using Injectable platelet-rich fibrin, Root canal treatment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Endodontic Disease, Root Canal Infection
Comparison of Antibacterial Efficacy of Three Final Irrigants
This study was conducted to determine the antibacterial affect of three different solutions used as final irrigant during endodontic therapy.
- Trial name
- NCT03853200
- Testing
- QMix Root Canal Irrigant, 17%EDTA+2%Chlorhexidine, EDTA
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences