Clinical trials: Self Harm
Suicidal Ideation
Effectiveness of a CBT Online-based Program to Reduce Suicide Ideation Among School Adolescents
This is a single-blind two armed cluster randomized controlled trial (cRCT) aimed to determine the effectiveness of an integrated blended intervention (online a face-to face sessions) to reduce suicidal ideation (primary…
- Trial name
- NCT05229302
- Testing
- Reframet IT, Usual care
- Where
- Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Talca
Depression
The Omega-3 Fatty Acid Paediatric Depression Trial
This study investigates the therapeutic efficacy and safety of omega-3 fatty acids rich in eicosapentaenoic acid / docosahexaenoic acid in pediatric depression in a nine months double-blind multi-centre study in 220 children and…
- Trial name
- Omega-3-pMDD (NCT03167307)
- Testing
- Omega 3 fatty acid
- Where
- 7 sites in Switzerland
- Volunteers
- 257 people
- Sponsor
- Gregor Berger
Self-Injurious Behavior, Mental Retardation
Self-Injury: Diagnosis and Treatment
Self-injurious behavior is behavior in which a person hurts or harms himself. This behavior sometimes occurs in people with mental retardation or autism.
- Trial name
- NCT00065936
- Testing
- Naltrexone hydrochloride, Transcutaneous sensory nerve stimulation
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Suicide
Text-based Support for Parents of Adolescents Following an Emergency Department Visits
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.
- Trial name
- TESP (NCT06660199)
- Testing
- Text-based intervention
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- University of Michigan
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Suicide, Attempted
Skills to Enhance Positivity in Suicidal Youth
This is a Hybrid Type I Effectiveness-Implementation design. Specifically, this study proposes to test the effectiveness of STEP in reducing suicidal events and ideation in 216 adolescents, admitted to inpatient psychiatric care…
- Trial name
- STEP (NCT04994873)
- Testing
- STEP, Enhanced TAU
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Brown University
Suicide Prevention, User Experience
Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813
Suicide remains a serious public health issue in Flanders. Every day, nearly three people die by suicide, and many more attempt it or struggle with suicidal thoughts.
- Conditions
- Suicide Prevention, User Experience, Suicide, Suicidal Ideation
- Trial name
- CHATQ-1813 (NCT07176156)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- University Ghent
Suicide Prevention
Adjunctive Team Enhanced Intervention to Improve Suicide Prevention Evidence-Based Practices in Primary Care
The purpose of the proposed study is to evaluate the feasibility and acceptability of a brief educational intervention (TEACH) that includes evidence-based strategies designed to improve task-specific teamwork and its impact (vs.
- Trial name
- NCT04606173
- Testing
- Team Education for Adopting Changes in Healthcare (TEACH)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Suicidal Ideation, Suicide, Attempted
Safety Planning in Juvenile Justice for Suicidal Youth
This study will examine the feasibility and acceptability of a program designed to conduct safety planning with youth in the juvenile justice system who are at risk for a suicide attempt and/or self-injury and to increase the…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self-injury
- Trial name
- Safety (NCT03655470)
- Testing
- Safety Planning, Standard care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Brown University
Self Harm
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Approximately 20% of young people experience self-harm behaviour in their lives. Self-harm can occur across different mental health disorders, and lead to negative outcomes and risk of suicide.
- Trial name
- PsiloIMAGINE (NCT06798636)
- Testing
- Psilocybin 5 mg with cognitive behavioural therapy intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Suicidal Ideation, Attempted Suicide
A Randomized Trial for Suicidal Patients
Although suicide risk is highly prevalent among the patient population in mental health care, remarkably little research exists on effective treatments. Among a small set of novel approaches, CAMS is particularly promising.
- Conditions
- Suicidal Ideation, Attempted Suicide, Suicide
- Trial name
- NCT02685943
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Vestre Viken Hospital Trust
Suicide, Attempted, Addiction
Suicide Attempts and Tramadol : a Case Report
In France, over the last years the use weak opioid analgesics decreased́, whereas that of strong opioid analgesics (OFMA). Hospitalizations for opioid overdose increased́ by 128% from 2000 to 2015, and deaths related to…
- Trial name
- NCT05075291
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Montpellier
COVID-19, Infections
Defining COVID-19 Infection Severity on Presentation to Hospital
In the assessment of severity in coronavirus disease 2019 (COVID-19), the modified Brit_x0002_ish Thoracic Society (mBTS)，CURB65 et al.
- Conditions
- COVID-19, Infections, Morality, Death, Assisted
- Trial name
- NCT05677789
- Testing
- Medical observation, Supportive treatment (BSC), Intensive care management
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Fuzhou General Hospital
Attempt Suicide
Genetic Variants Associated With Adolescent Suicide Attempts
Suicidal behaviors is known to aggregate in families. The purpose of this study is to evaluate association between common polymorphisms in genes important for neurobiological pathways linked to suicidal behaviors and suicide…
- Trial name
- VGTSA (NCT02001649)
- Testing
- SNP Genotyping
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Mental Health Disorder, Suicide Attempt
Efficacy of the I-CARE Digital Health Intervention
When presenting to an ED with suicide, self-harm or other mental health crises, youth may also experience "boarding", which is defined by the Joint Commission as "the practice of holding patients in the ED or another temporary…
- Conditions
- Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
- Trial name
- NCT07150832
- Testing
- Improving Care, Accelerating Recovery & Education (ICARE)
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Suicide
REACH VET Implementation Program Evaluation
The VA's Office of Mental Health and Suicide Prevention implemented an new program to increase suicide prevention outreach for Veterans at highest risk for suicide.
- Trial name
- REACH VET (NCT03280225)
- Testing
- External facilitation
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Nonsuicidal Self Injury, Self Hatred
Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
Participants (aged 13-16) will be randomized to: (1) an online, active control group program encouraging feelings disclosure (i.e.
- Conditions
- Nonsuicidal Self Injury, Self Hatred, Suicidal Thoughts, Suicide Attempts
- Trial name
- Project SAVE (NCT04498143)
- Testing
- Project SAVE ("Stop Adolescent Violence Everywhere") SSI, Active Comparator: Supportive Therapy ("Share Your Feelings") SSI
- Where
- United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- University of Denver
Self Injurious Behavior, Adolescent Behavior Problem
IMAGINATOR 2.0: Co-design and Early Evaluation of a Novel Blended Digital Intervention Targeting Self-harm in Young People
This study aims to investigate acceptability and feasibility of a new version of the Imaginator intervention, Imaginator 2.0, targeting self-harm behaviour in young people aged 12-25 under mental health services in the UK.
- Conditions
- Self Injurious Behavior, Adolescent Behavior Problem, Child Behavior Problem, Mental Health Disorder
- Trial name
- IMAG2 (NCT06311084)
- Testing
- Imaginator 2.0
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Imperial College London
Self Harm, Suicidal Idealtion
Self Harm in Females of South Asian Family Origin
Aim of the study is to adapt and develop a culturally appropriate psychological intervention and to pilot test it's feasibility, and acceptability for the adult South Asian females presenting to general hospital emergency…
- Conditions
- Self Harm, Suicidal Idealtion, Hopelessness
- Trial name
- NCT00884078
- Testing
- Culturally adapted manualized problem solving training
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Lancashire Care NHS Foundation Trust