Clinical trials: Sexual Risk
Hiv
TelePrEP for At-risk Youth in Colorado
Youth represent the largest proportion of new HIV infections in Colorado, reflective of their inadequate access and uptake of pre-exposure prophylaxis(PrEP)for HIV prevention.
- Trial name
- NCT05520905
- Testing
- TelePrEP
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV Infections
Hormonal Birth Control and the Risk of Acquiring HIV
The purpose of this study is to find out whether hormonal birth control increases, decreases, or does not change the risk of women becoming infected with HIV.
- Trial name
- NCT00006324
- Testing
- Ethinyl estradiol/levonorgestrel, Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 6,360 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV
Epidemiological Study of HIV in the South African National Defense Force
This project, called PHIDISA I, will screen uniformed personnel of the South African National Defense Force (SANDF) and their registered family members for HIV, hepatitis B and C, gonorrhea, syphilis, and chlamydia to determine…
- Trial name
- NCT00341887
- Where
- 5 sites in South Africa
- Volunteers
- 8,676 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Adherence, HIV Risk Behaviors
The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Risk Behaviors (Drug and Alcohol Use, Sexual Risk Behavior, Poor Adherence to Medications) Among HIV+ Youth. - 1
The purpose of this study is to conduct a pilot study of Motivational Enhancement Therapy (MET), an empirically validated behavioral change strategy, with young adults who are HIV +.
- Conditions
- Adherence, HIV Risk Behaviors, Alcohol & Drug Use, Health Behaviors
- Trial name
- NCT00227825
- Testing
- Motivational interviewing
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Teen Pregnancy, Contraception Behavior
Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters
The goal of this randomized control trial (RCT) is to assess an innovative adolescent pregnancy prevention program among youth that are at the highest risk of adolescent pregnancy, to prevent pregnancy and Sexually Transmitted…
- Conditions
- Teen Pregnancy, Contraception Behavior, Sexually Transmitted Diseases, Reproductive Health
- Trial name
- NCT05889689
- Testing
- Relationship Smarts Plus & Mind Matters, Relationship Smarts Plus alone, Preparing Adolescents for Young Adulthood (PAYA).
- Where
- United States
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Trinity Church Inc.
Exposure to Violent Event, Bullying
Electronic Pre-visit Questionnaire to Prompt Discussions of Youth Violence in Primary Care
Pediatricians are supposed to talk about youth violence at all heath supervision visits, however these types of conversations rarely occur. There have been no studies assessing tools to prompt these discussions.
- Trial name
- NCT02041182
- Testing
- Pre-Visit Questionnaire
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV Infections
Community Intervention Trial for Youth (CITY) Study
The purpose of this study is to test whether a multi-component, community-level, HIV-prevention intervention is more effective than existing HIV prevention activities in reducing unprotected anal intercourse (UAI) among men ages…
- Trial name
- NCT00164580
- Testing
- Community-Level Intervention
- Where
- 8 sites in United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Acquired Immunodeficiency Syndrome, Alcoholism
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
We propose to conduct a multifactorial genetic study of cancer risk-related behaviors and other complex human characteristics. The main areas of interest are tobacco smoking, excess alcohol consumption, psychological traits, and…
- Conditions
- Acquired Immunodeficiency Syndrome, Alcoholism, HIV Infection, Neoplasm
- Trial name
- NCT00001500
- Where
- United States
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
HIV Infection
Suicidality and Suicide Attempt Among HIV Patients on Efavirenz-containing Versus Efavirenz-free Antiretroviral Regimens
The purpose of this study was to compare the frequency of suicidality and suicide attempt among HIV patients starting treatment with Efavirenz and with patients starting treatment with other HIV medications.
- Trial name
- NCT02211807
- Volunteers
- 11,400 people
- Sponsor
- Bristol-Myers Squibb
Drug Abuse, HIV Infections
Neurobehavioral Model of HIV in Injection Drug Users
The purpose of this R01 study is to evaluate the association between neuropsychological executive dysfunction and HIV infection among young injection and non-injection drug users.
- Trial name
- NCT00198861
- Testing
- Injection and Non-Injection Drug Users
- Where
- United States
- Volunteers
- 836 people
- Sponsor
- The City College of New York
Pregnant Individuals, Aneuploidy
The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment
The goal of the ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) study is to compare the concordance of results of a novel non-invasive circulating fetal cell (CFC) assay to the results of…
- Conditions
- Pregnant Individuals, Aneuploidy, Down Syndrome (Trisomy 21), 22q11.2 Deletion Syndrome
- Trial name
- ADVANCE (NCT07643896)
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- BillionToOne Inc.
HIV, Sexually Transmitted Diseases
Project RESPECT: The Efficacy of HIV/STD Prevention Counseling
The efficacy of counseling to prevent infection with the human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) has not been definitively shown.
- Trial name
- NCT00362791
- Testing
- "Enhanced HIV/STD Counseling:" 4 face-to-face, interctive counseling sessions based on the Theory of Reasoned Action & Health Belief Model, "Brief Counseling" (aka "client-centered counseling"): 2 brief, face-to-face interactive sessions targeted a patient-identified risk behavior, "HIV Prevention Education": 2 brief, didactic sessions informing the patient about HIV/STD prevention strategies
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Trichomonas Vaginitis, Chlamydia Trachomatis
Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing
The purpose of this study is to determine the prevalence and treatment rates of T. vaginalis, C. trachomatis, and N. gonorrhoeae in women seeking emergency contraception or urine pregnancy testing in the Magee-Womens Hospital…
- Conditions
- Trichomonas Vaginitis, Chlamydia Trachomatis, Neisseria Gonorrhoeae Infection
- Trial name
- NCT00978848
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Infections, Papillomavirus
Post-marketing Study to Assess the Safety of CERVARIX When Used in the United States and in Canada
This study will assess the risk of spontaneous abortion during weeks 1-19 of gestation, and other pregnancy outcomes, in an Exposed vaccinated cohort, i.e.
- Trial name
- NCT01290393
- Testing
- Data collection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Risky Sexual Behavior, Emotional Regulation
Education Program to Reduce Risky Behavior in Adolescents Ph I
This phase will complete the TRAC adaptation to a web app. The pilot study (R21 HD089979) effectively translated the ER content of TRAC and the same procedures will be used to translate the remaining content.
- Conditions
- Risky Sexual Behavior, Emotional Regulation, Adolescent Behavior
- Trial name
- iTRAC (NCT05607784)
- Testing
- Formative Research- Content Translation, Formative Research- Content Feedback and Acceptability
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Klein Buendel, Inc.
HIV/AIDS
Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration
HIV prevalence among incarcerated youth living with HIV (YWH) is three times that of the general population and one in seven of all persons with HIV experience incarceration each year.
- Trial name
- LINK2 (NCT03584932)
- Testing
- LINK2 Youth Services Navigation Intervention
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of California, Los Angeles
HIV, Chlamydia
National Rapid TLC: Testing and Linkage to Care
The goal of this cross-sectional study is to learn if the GeneXpert system is a practical system for HIV and STBBI testing in community-based organizations and health clinics.
- Conditions
- HIV, Chlamydia, Gonorrhea, HCV
- Trial name
- NCT07730801
- Testing
- Xpert® HIV-1 Qual XC
- Where
- 2 sites in Canada
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV Prevention
PrEP Restart for Adolescent Girls and Young Women Using STI Self Testing and Assessment of Risk
This is a pilot randomized trial among 50 AGYW (aged ≥16≤18 years), who discontinued PrEP use within the past 6 months, assigned in a 1:1 ratio to receive: 1) STI self-test kits (Neisseria gonorrhoea (NG), Chlamydia trachomatis…
- Trial name
- PALESA (NCT06030856)
- Testing
- STI test kits (NG, CT and TV) for home use, Self Administered Behavioural Risk Assessment
- Where
- South Africa
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wits RHI Research Centre Clinical Research Site
Smoking, Sexual Behavior
Linking Lives: Building Quality Parent Components for School-Based Health Programs in Middle Schools
The purpose of this study is to develop and evaluate the effectiveness of a parent-based intervention that can be implemented in conjunction with existing school-based programs designed to prevent or reduce sexual risk behavior…
- Trial name
- NCT00136279
- Testing
- Linking Lives parent-based intervention
- Where
- United States
- Volunteers
- 9,510 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections, Viremia
Enhanced Virologic Monitoring for Pregnant and Postpartum Women With HIV
The goal of this study is to learn about supporting pregnant and postpartum women living with HIV with treatment adherence. The investigators will conduct a pilot study of an intervention that includes peer counseling about viral…
- Conditions
- HIV Infections, Viremia, Pregnancy Related
- Trial name
- NCT05845619
- Testing
- Enhanced virologic monitoring
- Where
- 4 sites in Kenya
- Volunteers
- 550 people
- Sponsor
- University of California, San Francisco