Clinical trials: Short-chain Fatty Acids
Prematurity, Low Birth Weight Neonates
Metagenomic & Metabolomic Study: Bifidobacterium Probiotic Effects on Gut Microbiota & SCFA in Preterm NICU Infants
One million premature babies die due to prematurity complications, contributing the most to the causes of death in children under 5 years old.
- Trial name
- NCT07213414
- Testing
- Probiotics
- Where
- 3 sites in Indonesia
- Volunteers
- 72 people
- Sponsor
- Hasanuddin University
Iron Deficiency Anemia
Effect of Cow's Milk Kefir on Short Chain Fatty Acid (SCFA), Haemoglobin, and Ferritin Levels of Anemic Adolescent Girls
Introduction: The prevalence of anemia among adolescent girls in Indonesia is still quite high. According to the Indonesian Health Survey (IHS) in 2023, it was 18% and is still a national problem.
- Trial name
- NCT06957717
- Testing
- cow's milk kefir, pasteurized cow's milk
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lusyana Gloria Doloksaribu
Child Development
Study of the Effects of Soy Exposure in Early Life on Bone Development and Gut Microbiota
In this project, the investigators aim to investigate the effects of soy consumption at early life on the development of gut microbiota and bone growth.
- Trial name
- NCT05763589
- Testing
- No intervention is involved
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The Hong Kong Polytechnic University
Aerobic Endurance, Metabolism
Effect of Short-chain Fatty Acids on Aerobic Endurance
Randomized, double-blind, placebo-controlled crossover study designed to determine the effects of increasing colonic short-chain fatty acid (SCFA) content on aerobic endurance in healthy adults, and to identify underpinning…
- Trial name
- NCT06054607
- Testing
- High-amylose maize starch+acetate/butyrate, Low-amylose maize starch
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Healthy Mothers, Healthy Infants
Maternal High Fibre Fermented Diet Effect on Breastfed Infant Gut Microbiome
Breastfeeding is recommended for babies from birth to six months old because breast milk provides all the nutrients babies need for growth and development.
- Trial name
- MumBabyGut (NCT06977113)
- Testing
- High Fibre Fermented Food Diet, Control Habitual Diet
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Short Chain Fatty Acids Concentration in Breast Milk
Study on Short Chain Fatty Acids Concentration in Breast Milk and Its Correlation With the Maternal Diet
The purpose of this study is to determine whether the acetate, butyrate and propionate concentration in breast milk and to evaluate the possible correlation of these concentrations with maternal diet.
- Trial name
- NCT02301728
- Testing
- sampling of breast milk, obtaining information about the maternal diet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federico II University
Breastfeeding, Exclusive
Profile of Human Milk Oligosaccharides and FUT2 Polymorphism of Mothers in Indonesia
Human milk oligosaccharides (HMOs), the third most abundant constituent of breastmilk, are known to have beneficial effects on infant immunity. Maternal genetic polymorphisms cause HMO variability.
- Trial name
- NCT05156255
- Where
- Indonesia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Child Development
Soy Exposure on Bone Development and Gut Microbiota
In this project, the investigators aim to investigate the effects of soy consumption at early life on the development of gut microbiota and bone growth.
- Trial name
- NCT05213780
- Testing
- No intervention is involved
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Microbial Colonization, Gut Microbiota
Diet Supplementation With Prebiotics to Improve Gut Health in Egyptian Children
The study described herein seeks to assess the extent to which diet supplementation of young Egyptian children, one of the most vulnerable groups to the risk of diarrhea, with prebiotic fiber can improve their gut health.
- Trial name
- NCT06561724
- Testing
- Biscuits maltodextrin, Biscuits includes prebiotics tartoufa inulin, Biscuits includes prebiotics chicory inulin
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Anorexia Nervosa
The Role of Short-chain Fatty Acids in Malnutrition on Stress, Eating Behavior, and Nutritional State
This clinical trial aims to test the psychobiological effects of certain substances produced by gut bacteria, known as short-chain fatty acids (SCFAs), in people with anorexia nervosa.
- Trial name
- NCT06064201
- Testing
- Short-chain fatty acids (SCFAs)
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- KU Leuven
Eating Disorders in Adolescence, Eating Disorders in Children
A Study of the Intestinal Microbiota in Children and Adolescents With Eating Disorders. A Perspective From Psychoneuroimmunology
The goal of this observational study is to learn if behavioral and psychological factors are associated with the intestinal microbiota composition and function in children and adolescents with eating disorders (ED).
- Trial name
- PSYNIGED (NCT07066033)
- Where
- 2 sites in Spain
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Esther Nova
Metabolic Syndrome
Effects of Probiotics on Metabolic Syndrome ,Intestinal Microflora and SCFA.
The improvement effects of GLAC biotech probiotics contains 5 specialized strains on the biochemical analysis and gut microbiota will be verified in the clinical trial through cooperation with the ADPRC.
- Trial name
- NCT06183801
- Testing
- Probiotics 1, Probiotics 2, Probiotics 3
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Glac Biotech Co., Ltd
Parkinson Disease
Prebiotics in the Parkinson's Disease Microbiome
There are about one million Parkinson's disease (PD) patients in America. The risks associated with whether or not an individual may develop PD include environment and genetic (biologic, hereditary) factors.
- Trial name
- NCT04512599
- Testing
- Prebiotic Bar
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rush University Medical Center