Clinical trials: Sickness Behavior, open to volunteers
Depression, Cancer
Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)
The purpose of this study is to develop and test a new intervention to reduce depressive symptoms in post-treatment cancer participants.
- Conditions
- Depression, Cancer, Stage III Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT06811454
- Testing
- MINDSET, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Case Comprehensive Cancer Center
Malnutrition, Infant, Breastfeeding, Exclusive
Providing Breastfeeding Support After Discharge From Hospital to Improve Growth and Development of Malnourished Infants
The current guidelines used to manage malnutrition among infants aged below 6 months (u6m) recommend that infants admitted to hospital with malnutrition be supported to reestablish exclusive breastfeeding before discharge.
- Trial name
- IBAMI-2 (NCT06372418)
- Testing
- Breastfeeding peer support intervention, Standard Care
- Volunteers
- 250 people
- Sponsor
- University of Oxford
Stigma of Mental Illness, Cancer
Healthcare Providers' Attitudes Toward Oncology Patients With Mental Disorders
ONCO-MinD is a multicentre, cross-sectional, non-interventional mixed-method study aimed at investigating healthcare providers' attitudes towards oncology patients with mental disorders in Italian cancer centres.
- Conditions
- Stigma of Mental Illness, Cancer, Psychiatric Comorbidity
- Trial name
- ONCO-MinD (NCT07748221)
- Testing
- OMS-HC Questionnaire and Semi-Structured Interviews
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Serious Mental Illness, Tobacco Use Disorder
Facilitation to Increase Tobacco Treatment
Smoking disproportionally impacts Veterans, and VA spends $2.7 billion annually on smoking-related health conditions. Veterans with serious mental illness (SMI) smoke tobacco products at triple the rate of Veterans without any…
- Trial name
- FITT (NCT07455526)
- Testing
- Multi-component facilitation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Critical Illness, Gender Equality
Ethnic and Gender Based Admittance Patterns in the ICU
The dominating proportion of patients in the ICU are men. Studies indicate that men receive more mechanical ventilation, vasoactive drugs, renal replacement therapy, invasive monitoring and have longer length of stay in the ICU.
- Conditions
- Critical Illness, Gender Equality, Discrimination, Sex, Discrimination, Racial
- Trial name
- EGAP-ICU (NCT05513456)
- Testing
- Randomization to a different factors in the case descriptions
- Where
- Sweden
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Heat Illness, Quality of Life
Structural Heat Adaptation and Education in Rural Setting
This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and quality of life during periods of extreme…
- Trial name
- SHAPES (NCT06983483)
- Testing
- Community education and awareness, Participatory local structural and environmental heat mitigation solutions
- Where
- Pakistan
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Depression
Treatment Interrupts Depression Early
The TIDE project aims to establish personal indicators for initial treatment choice for youth with first episode depression. Specifically, 100 adolescents and young adults (age 12 to 25) with untreated major depressive disorder…
- Trial name
- TIDE (NCT05002309)
- Testing
- Cognitive-Behavioural Therapy, Antidepressant medication
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Nova Scotia Health Authority
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Mood Disorder
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder
This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability…
- Trial name
- NCT00025935
- Testing
- Lithium
- Where
- United States
- Volunteers
- 2,350 people
- Sponsor
- National Institute of Mental Health (NIMH)
Loneliness, Mental Well-being
Creating Encounters Between Generations - Together Instead of Alone (GemsE)
Elderly people and children and young people (CYP) and from families with mentally ill parents are particularly affected by loneliness.
- Conditions
- Loneliness, Mental Well-being, Health-related Quality of Life
- Trial name
- GemsE (NCT07581171)
- Testing
- Mechanisms and effectiveness of intergenerational tandems
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Critical Illness, Neurologic Disorder
The "What Is Important to Us" Communication Intervention Pilot Clinical Trial
The objective of this study is to conduct a pilot randomized controlled trial (RCT) of a photo-narrative communication intervention developed by our study team with patients/parents of children with severe neurological impairment…
- Trial name
- NCT06208332
- Testing
- "What Is Important to Us" Communication Intervention
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Seattle Children's Hospital
Health Care Transition Readiness, Health Literacy
Health Care Transition Readiness Short-Form Video Intervention
The goal of this clinical trial is to assess whether social-media style short-form health education videos can increase health care transition readiness, self-efficacy, emotional well-being, health literacy, and appointment…
- Conditions
- Health Care Transition Readiness, Health Literacy, Self Efficacy, Emotional Wellbeing
- Trial name
- NCT06842576
- Testing
- Health Education Videos, GotTransition.org Website
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Los Angeles
Behavioral Activation, Major Depressive Disorder
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
The purpose of this study is to identify and validate a panel of genetic markers associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioural activation in children and youth with major depressive disorder…
- Conditions
- Behavioral Activation, Major Depressive Disorder, Anxiety Disorders, Antidepressant Drug Adverse Reaction
- Trial name
- PGx-SImBA (NCT06763081)
- Testing
- Not applicable- observational study
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- University of Manitoba
Medication Adherence
Adaptive Cell Phone Support (ACPS)
The goal of this pilot clinical trial is to test a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions.
- Trial name
- ACPS (NCT07064824)
- Testing
- Adaptive Cell Phone Support, Computer-Delivered Cell Phone Support, Automated Text Reminders
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Children's Hospital Los Angeles
Healthy Subjects (HS)
Evaluation of the Effectiveness of Teen Mental Health First Aid in Secondary School Students in Hong Kong
Mental health problems in adolescents are on the rise worldwide especially after COVID -19 pandemic. Early detection and intervention should help to reduce the adverse impact of the mental illness on the adolescent.
- Trial name
- tMHFA-HK (NCT07195890)
- Testing
- A course of teen Mental Health First Aid to be provided to participants
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TN Foo Centre for Positive Mental Health
Behavioral Monitoring in ICU, Prediction of Accidental Events Using AI-Assisted Video Analysis
Exploring the Use of AI-Assisted Video Monitoring to Predict Accidental Events in ICU Patients
This study aims to improve the safety and care of patients in the Intensive Care Unit (ICU) by using artificial intelligence (AI) to analyze video monitoring.
- Conditions
- Behavioral Monitoring in ICU, Prediction of Accidental Events Using AI-Assisted Video Analysis, ICU Patient Safety and Early Warning System
- Trial name
- AIME-ICU (NCT07307521)
- Testing
- AI-Assisted Video Monitoring
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Critical Illness Recovery, Mental Health
Building Resilience Through Anxiety Virtual Education in PICU Survivors
Survivors of Pediatric Intensive Care Unit (PICU) admissions often experience adverse mental health consequences, either as a result of, or associated with, their intensive care stay.
- Trial name
- BRAVE-PICU (NCT07906366)
- Testing
- Digital Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Rochester
Mental Health, Mental Health Literacy
Mental Health Literacy and Help-Seeking Behavior Among Adolescents
This study examines mental health awareness and help-seeking behaviors among adolescents aged 13-18 years in Assiut City, Egypt.
- Conditions
- Mental Health, Mental Health Literacy, Stigma of Mental Illness, Help-Seeking Behavior
- Trial name
- NCT07395245
- Testing
- School-Based Mental Health Literacy Educational Program
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Heat Illness, Quality of Life
Structural Heat Adaptation and Education in Urban Setting
This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and improve quality of life during periods of…
- Trial name
- SHAPES (NCT06991543)
- Testing
- Community education and awareness, and personal lifestyle and cooling behavior modification, Participatory local structural and environmental heat mitigation solutions
- Where
- Pakistan
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Aga Khan University