Clinical trials: Sinus Disease
Acute Otitis Media (AOM)
Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media)
This study is being conducted at multiple hospitals and clinics to better understand whether antibiotics truly help children feel better when they have an ear infection (acute otitis media).
- Trial name
- MEASURE (NCT07730814)
- Testing
- Amoxicillin, Amoxicillin-Clavulanate
- Where
- 5 sites in United States
- Volunteers
- 1,100 people
- Sponsor
- Nader Shaikh
Head and Neck Cancer, Pain
Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
RATIONALE: Acupuncture may help relieve pain and dysfunction caused by cancer surgery. It is not yet known whether acupuncture is more effective than standard therapy in treating pain and dysfunction in patients who have…
- Trial name
- NCT00090337
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Emergence Agitation
Comparison of Effect of Dexmedetomidine and Midazolam on Emergence Agitation
Since the frequency of emergence agitation (EA) is relatively high in children while undergoing nasal surgery, and there is not much data available in Pakistan regarding EA in adults undergoing functional endoscopic sinus surgery…
- Trial name
- NCT07392983
- Testing
- Dexmedetomidine, Midazolam
- Where
- 2 sites in Pakistan
- Volunteers
- 146 people
- Sponsor
- Muhammad Aamir Latif
Vesico-vaginal Fistula
Treatment of Vesico-vaginal Fistula by a Robot Assisted Laparoscopy : Results of a Multicentric Series (FFVLARO)
Robot-assisted Vesico-Vaginal fistula (VVF) repair was described a few years ago as an alternative to the open approach to minimize the morbidity of this surgery.
- Trial name
- FFVLARO (NCT04172389)
- Testing
- vesico-vaginal fistula robot assisted laparoscopic repair
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Central Hospital, Nancy, France
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Laryngeal Cancer
Study of the Risk of Pharyngocutaneous Fistula in a Population of Patients Undergoing Total Laryngectomy and Creation of a Score for Pre-operative Risk Stratification.
Multicenter retrospective study of a cohort of patients affected by laryngeal carcinoma and subjected to total laryngectomy surgery at the centers participating in the reference period and responding to inclusion criteria.
- Trial name
- NCT06308016
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Regina Elena Cancer Institute
Arteriovenous Fistula
Color Doppler Ultrasonography in Prediction of Arteriovenous Fistula Maturation in Hemodialysis Patients
The transplant is the definitive treatment of renal insufficiency, in our days. While waiting for it, the arteriovenous fistula surgery is standard procedure.
- Trial name
- NCT03171701
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Female Genital Fistula, Incontinence
Adverse Outcomes Following Female Genital Fistula Repair
Following genital fistula repair, fistula repair breakdown and recurrence, persistent and incidence incontinence are major adverse outcomes, limiting women's health and wellbeing.
- Trial name
- Mulisa (NCT05437939)
- Where
- Uganda
- Volunteers
- 802 people
- Sponsor
- University of California, San Francisco
Sinusitis
Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children
The investigators objective is to compare short course (5 days) to long course (14 days)antibiotics for the treatment of acute bacterial sinusitis in children.
- Trial name
- NCT01166945
- Testing
- Amoxicillin-Potassium Clavulanate Combination
- Where
- 2 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of Wisconsin, Madison
Pilonidal Sinus, Recurrence
Off-midline Closure Errors as a Risk Factor for Recurrence Following Limberg Flap in Patients With Pilonidal Sinus
Background. Limberg flap, one of the recently being popularized off-midline closure techniques, is widely performed for the treatment of sacrococcygeal pilonidal sinus; however, recurrences still can be seen. Objective.
- Trial name
- NCT02663466
- Testing
- erroneous off-midline closures
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Medical Park Gaziantep Hospital
Pilonidal Sinus
Umblical Pilonidal Sinus Evaluation
Purpose: Pilonidal sinus disease (PSD) is a chronic inflammatory condition of skin due to implanted loose hair. PSD is commonly seen in sacrococcygeal region, but can also be seen in axilla, perineum, suprapubic regions, on hands…
- Trial name
- NCT04856605
- Testing
- surgery
- Volunteers
- 82 people
- Sponsor
- Istanbul Medeniyet University
Cystic Fibrosis, Rhinosinusitis
Tobramycin Delivered by Nebulized Sonic Aerosol for Chronic Rhinosinusitis Treatment of Cystic Fibrosis Patients
Patients with cystic fibrosis frequently develop chronic rhinosinusitis. Bacterial colonization is facilitated by a reduced mucociliary function and some previous studies suggest that the microbiology of the upper airways might…
- Conditions
- Cystic Fibrosis, Rhinosinusitis, Lung Diseases
- Trial name
- AVASMUC (NCT02888730)
- Testing
- Tobramycin nebulized nasally, Physiologic serum nebulized nasally
- Where
- 6 sites in France
- Volunteers
- 86 people
- Sponsor
- Virginie ESCABASSE
Cancer
Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation
RATIONALE: Captopril may protect the lungs from the side effects of bone marrow or stem cell transplantation. PURPOSE: Randomized phase III trial to determine the effectiveness of captopril to lessen the side effects in patients…
- Trial name
- NCT00004230
- Testing
- captopril, cyclophosphamide, autologous bone marrow transplantation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Northwestern University
Sinus Bradycardia, Atrioventricular Block
Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
Heart transplants save the lives of nearly 500 children in heart failure per year. Columbia is one of the largest pediatric heart transplant centers in the world, averaging 25 transplants per year, and providing ongoing care to…
- Trial name
- NCT02462941
- Testing
- Adenosine, Cardiac catheterization
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
Anal Fistula
Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain
comparison between to groups of patients with simple anal fistula one group underwent sistulotomy the other underwent fistulotomy and marsupialization of the wound edges , the investigator tested the incidence of postoperative…
- Trial name
- NCT04155905
- Testing
- fistulotomy and marsupialization of wound edges, fistulotomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Intracranial Aneurysm, Brain Arterial Disease
Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
BALT has designed an electronic platform to continue collecting clinical data as part of the post-marketing clinical follow-up of its devices.
- Conditions
- Intracranial Aneurysm, Brain Arterial Disease, Acute Ischemic Stroke, Peripheral Vascular Diseases
- Trial name
- EVIDENCE (NCT04927156)
- Testing
- BALT medical devices
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Balt Extrusion
Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.
Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects.
- Conditions
- Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus, Anomalous Coronary Artery Course, Anomalous Coronary Artery with Aortic Origin and Course Between the Great Arteries
- Trial name
- NECESSARY (NCT05159791)
- Testing
- Invasive coronary blood flow assessment and simulations and fluid dynamic patient specific simulation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato
Pancreatic Fistula
Evaluation of a Novel Pancreaticojejunostomy Technique for Pancreaticoduodenectomy
Pancreaticoduodenectomy is a surgical procedure for removing cancer in the pancreas, the bile system or the duodenum that is associated with a high rate of complications.
- Trial name
- NCT01696903
- Testing
- Pancreaticojejunostomy technique
- Where
- 2 sites in Sweden
- Volunteers
- 123 people
- Sponsor
- Karolinska Institutet
Anorectal Fistula
Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas
The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-[X]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for…
- Trial name
- NCT03321266
- Testing
- Cook Biodesign® Fistula Plug
- Where
- 4 sites in United States, Germany
- Volunteers
- 79 people
- Sponsor
- Cook Group Incorporated
Asthma
Charcot Leyden Crystals in Pathology
Charcot Leyden crystals (CLC) are sometime reported in pathological reports of airway or sinonasal samples but their clinical significance remain elusive.
- Trial name
- CLCpath (NCT03999242)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier