Clinical trials: Sinus Surgery
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Pilonidal Sinus
Study on Surgical Treatment of Pilonidal Sinus Disease
Comparison of limited excision-primary closure, Limberg, and modified Limberg flap techniques for the surgical treatment of pilonidal sinus disease, each performed by a separate surgeon, in terms of postoperative outcomes and…
- Trial name
- NCT02849197
- Testing
- surgery for pilonidal sinus disease
- Volunteers
- 802 people
- Sponsor
- Bezmialem Vakif University
Pulmonary Arteriovenous Malformation, Congenital Disorders
A Review of Surgical Management of Congenital Pulmonary Airway Malformations (CPAM): A Decade of Experience
Congenital pulmonary malformation in children is a rare abnormality mostly diagnosed before birth during antenatal ultrasound examinations.
- Trial name
- CPAM (NCT04449614)
- Testing
- Thoracoscopic CPAM resection
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- King's College Hospital NHS Trust
Evaluate and Compare Between Excision and Primary Closure Procedure and Rhomboid Flap Technique for the Treatment of Pilonidal Sinus, Duration of Operation,
Rhomboid Flap Versus Primary Closure After Excision of Sacrococcygeal Pilonidal Sinus. (A Prospective Randomized Study)
To evaluate and compare between excision with primary closure of wound and excision with Rhomboid flap reconstruction in the treatment of pilonidal sinus as regard duration of operation, healing time, hospital stay, complications…
- Trial name
- non (NCT01223599)
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula
Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery
The study is primarily a descriptive study examining the physiological, ventilatory, surgical, and recovery effects of patients ≤ 6 months of age who undergo thoracoscopic surgery and to determine the accuracy of transcutaneous…
- Conditions
- Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula, Esophageal Atresia
- Trial name
- NCT02033772
- Testing
- Thoracoscopic surgery
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Arlyne Thung
Chronic Rhinosinusitis
Early Saline Irrigation to Decrease Post-operative Endoscopic Debridement
Nasal saline is a common treatment adjunct in the post-operative setting for endoscopic sinus surgery. However, the ideal timing and quantity of irrigation in the early post-operative period remains unknown.
- Trial name
- NCT01943370
- Testing
- Early saline irrigation, Routine Irrigation
- Volunteers
- 25 people
- Sponsor
- University of Alberta
Hypospadias, Distal Penile Hypospadias (Disorder)
Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomized Trial
This randomized controlled trial evaluates the effect of adding Byar's flap in combination with double dartos flap coverage during tubularized incised plate (TIP) urethroplasty in children with distal hypospadias.
- Trial name
- DD-TIP-BF (NCT07525570)
- Testing
- Double Dartos Flap Coverage, Byar's Flap + Double Dartos Flap
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Javaid Afridi
Sacrococcygeal Pilonidal Sinus
Effectiveness of Different Surgical Techniques for Curative Treatment of Pilonidal Sinus Disease in the Pediatric Population
Pilonidal sinus disease (PSD) in children is associated with significant morbidity and recurrence risk. Multiple surgical techniques are used, including excision with open healing, primary midline closure, off-midline closure…
- Trial name
- PiloPedia (NCT07470294)
- Testing
- Surgical treatment for pilonidal sinus disease, including various techniques including excision with or without primary closure, or endoscopic techniques.
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Oroantral Fistula
A Pedicled Buccal Periosteal Flap for the Closure of Oro-antral Fistula
The aim of this study is to evaluate both clinically and radiologically the efficacy of using the pedicled buccal periosteal flap for closure of oroantral fistula without affecting the original intraoral anatomy.
- Trial name
- NCT05987943
- Testing
- A Pedicled Buccal Periosteal Flap for the Closure of Oro-antral Fistula
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Marwa Taha Ibrahim
Breast Cancer, Colorectal Cancer
Positron Emission Tomography/Computed Tomography Scanning Before Surgery in Patients With Non-Small Cell Lung Cancer, Colorectal Cancer, Breast Cancer, Esophageal Cancer, or Head and Neck Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography/computed tomography (PET/CT) scanning before surgery, may help measure the extent of disease.
- Conditions
- Breast Cancer, Colorectal Cancer, Esophageal Cancer, Head and Neck Cancer
- Trial name
- NCT01254591
- Testing
- 18F-fluoromisonidazole, fluorescence angiography, laboratory biomarker analysis
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University College London (UCL) Cancer Institute
Pilonidal Sinus
Fistulectomy vs. Modified Karydakis Procedure for Pilonidal Sinus
This study wants to improve patient care affected by pilonidal sinus during and after surgery. Pilonidal sinus excision is a frequent procedure, despite this, there is still not an appropriate surgical technique because of a lack…
- Trial name
- NCT03271996
- Testing
- Primary closure, Fistulectomy
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Dimitri Christoforidis
Surgical Hemostasis
Comparative Study Between the Effect of Dexmedetomidine ,Midazolam or Bupivacaine Packing During FESS on Surgical Field Visualization
The goal of this interventional study is to compare the nasal packing with dexmedetomidine .midazolam or bupivacaine on surgical field visualization during FESS .
- Trial name
- FESS (Function (NCT07013955)
- Testing
- Saline, Dexmedetomidine, Midazolam
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Minia University
Spinal Cord Vascular Diseases
Surgical Intervention of Spinal Arteriovenous Malformations and Fistulas
Spinal arteriovenous fistulas (AVFs) and arteriovenous malformations (AVMs) are complex neurosurgical lesions that are very challenging to manage.
- Trial name
- SUIT-SAVM (NCT03024749)
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Hongqi Zhang, MD
Vestibular Fistulae
Rectovestibular Fistula Which Surgical Approaches?
This study was a prospective, randomized, comparative study that included female children with rectovestibular fistulae who were selected from patients with anorectal malformations treated at the pediatric surgical unit, Assiut…
- Trial name
- Vestibanus (NCT04970160)
- Testing
- TSARP, PSARP, Classic ASARP
- Volunteers
- 84 people
- Sponsor
- Aswan University Hospital
Tracheo Esophageal Fistula, Congenital Diaphragmatic Hernia
Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries
the aim of this study is to compare the effect of different modes of mechanical ventilation by using volume-controlled ventilation and pressure-controlled ventilation on cerebral blood flow monitored by cerebral oximetry during…
- Trial name
- NCT04507295
- Testing
- cerebral oximetry ( INVOS 5100 )
- Volunteers
- 30 people
- Sponsor
- Cairo University
Hypospadias
The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery.
Post-operative tissue oedema is one of the main causes of failure of hypospadias repair. Severe oedema may disrupt the suture line, invite infection and result in repair failure.
- Trial name
- NCT04196400
- Testing
- steroid betamethasone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Meningitis and Sinusitis in Transnasal Surgery
Effectiveness of Preoperative Antiseptic Preparation in Transnasal Skull Base Surgery
Objective: Transnasal skull-base surgery is a complex and invasive procedure that involves the use of preoperative antiseptic preparations.
- Trial name
- NCT06313281
- Testing
- Preoperative Antiseptic preparation prior to transnasal skull base surgery
- Where
- Saudi Arabia
- Volunteers
- 142 people
- Sponsor
- King Saud University
Postprocedural Gastric Stasis
Gastric Emptying After Infracolic or Supracolic Gastrojejunostomy Following Pancreaticoduodenectomy
Patients undergoing whipples pancreaticoduodenectomy tend to develop delayed gastric emptying. The study compares two types of anastamosis of stomach to jejunum (supracolic and infracolic) and compares whether it influences the…
- Trial name
- NCT01191138
- Testing
- Infracolic gastrojejunal anastamosis, Supracolic gastrojejunal anastamosis
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Asian Institute of Gastroenterology, India
Functional Endoscopic Sinus Surgery
Effect of Functional Endoscopic Sinus Surgery On Eustachian Tube Function in Patients With Nasal Polypi
This study is conducted to : Correlate the incidence of ETD with nasal polypi. To evaluate the effects of functional endoscopic sinus surgery on eustachian tube function in patients with nasal polypi
- Trial name
- NCT05053906
- Testing
- Endoscope
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pilonidal Sinus, Pilonidal Disease
Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone)
The goal of this randomized clinical trial is to establish the efficacy of 'pit picking with laser therapy' versus 'pit picking alone' on both short and long-term outcomes in patients of 12 years and older with primary pilonidal…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Pilonidal Sinus of Natal Cleft, Pilonidal Disease of Natal Cleft
- Trial name
- LA POPA (NCT06140199)
- Testing
- Pit-picking surgery, Pit-picking surgery with Sinus Laser assisted Closure
- Volunteers
- 482 people
- Sponsor
- dr. IJM Han-Geurts