Clinical trials: Soft Tissue Injuries
Finger Injuries, Soft Tissue Injuries
Repair of Multiple Finger Defects Using the Dorsal Homodigital Island Flaps
Multiple finger defects are common in hand trauma and result in functional disability. These injuries are often complex and severe, and thus reconstructive alternatives are limited.
- Trial name
- NCT01767727
- Testing
- Soft tissue coverage
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University
Osteosarcoma, Pediatric
Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
Retrospective analysis of specific characteristics of complications and long-term oncological and function outcomes in lower-limb osteosarcoma pediatric patients.
- Conditions
- Osteosarcoma, Pediatric, Lower Limb Injury, Outcome
- Trial name
- NCT06162962
- Testing
- Retrospective analysis
- Where
- China
- Volunteers
- 345 people
- Sponsor
- Changye Zou
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Melanoma, Sarcoma
Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity
Hyperthermic isolated limb perfusion with melphalan alone is administered as a double perfusion schedule. These two isolates limb perfusions with melphalan are treated 3-6 weeks apart.
- Trial name
- NCT00001577
- Testing
- double isolated limb perfusion with melphalan alone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Osteosarcoma, Ewing's Sarcoma Family of Tumors
Markers of Anthracycline-Related Cardiac Muscle Injury
Anthracycline antibiotics are included in the chemotherapy regimens of approximately 82% of patients with bone cancer and 44% of those with soft tissue sarcoma diagnosed in childhood or adolescence.
- Conditions
- Osteosarcoma, Ewing's Sarcoma Family of Tumors, Rhabdomyosarcoma, Non-rhabdomyosarcoma Soft Tissue Sarcomas
- Trial name
- NCT01112800
- Sponsor
- St. Jude Children's Research Hospital
Open Wound of Lower Limb
Comparison of Distally Based Sural Artery and Supramalleolar Flap for Coverage of Dorsum of Foot and Ankle Defects
Our main aim for this study was to evaluate the long-term outcome comparisons between sural artery and Supramalleolar flap in the reconstruction of extensive defects of non-weight bearing regions of foot and ankle.
- Trial name
- NCT05027542
- Where
- Pakistan
- Volunteers
- 53 people
- Sponsor
- Abeer Musaddiq
Soft Tissue Injuries
Bilaterally Innervated Sensory Dorsal Digital Flaps for Sensory Reconstruction of the Fingers
Sensory coverage in the finger continues to be a challenging problem. This study reports sensory reconstruction of the fingers with the bilaterally innervated dorsal digital flaps and compares the results between the dual- and…
- Trial name
- NCT02167646
- Testing
- Flap including bilateral nerve branches
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Soft Tissue Injuries
Effectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in Children
Local anaesthesia is considered one of the most alarming and non-comfortable dental procedures for children. This goes back to the persisting effect of the local anaesthesia after finishing dental procedures.
- Trial name
- NCT05448807
- Testing
- OraVerse
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Balanced, Soft Tissue Injuries
Effects of Soft Tissue Mobilization and Vibration Therapy in Competitive Rowers
This randomized controlled study aims to investigate the effects of instrument-assisted soft tissue mobilization (IASTM) and percussion massage therapy on balance, explosive strength, and functional performance in competitive…
- Trial name
- NCT07004374
- Testing
- a percussion massage gun, specially designed stainless-steel instruments
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Athletic Injuries, Eczematous Skin Diseases
Using Hydrating Cream to Improve Repeated Hand Skin Injury Among Tug-of-war Players
Athletes commonly face skin injuries during training and competition, which can negatively impact their performance and physical health.
- Conditions
- Athletic Injuries, Eczematous Skin Diseases, Skin Avulsion
- Trial name
- NCT05861713
- Testing
- Hydrating Cream
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Soft Tissue Inflammation
Prevention of Hypergranulation Tissue After Gastrostomy Tube Placement
The primary objective of this study is to compare the incidence of postoperative hypergranulation tissue formation after gastrostomy tube placement among children randomized to one of three treatments, in addition to measuring…
- Trial name
- NCT01501539
- Testing
- Standard Hydrocolloid Dressing, Silver Hydrocolloid Dressing
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Fracture, Osteomyelitis
Treatment of Fracture Related Infection in Latin America.
Postoperative bone infection is a severe complication in the treatment of fractures and is more frequent than in elective joint replacement surgeries.
- Conditions
- Fracture, Osteomyelitis, Soft Tissue Injuries, Bone Loss
- Trial name
- NCT05467644
- Testing
- Treatment of Fracture Related Infection
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- Manoel Victorino Hospital
Wounds
Negative Pressure Wound Therapy With the Engenex™-Pump and Bio-Dome™ Dressing, an Evaluation
Negative pressure wound therapy (NPWT) has become a powerful tool in wound bed preparation of complex wounds and is routinely used in various disciplines, including general surgery and plastic surgery.
- Trial name
- NCT01107821
- Testing
- Engenex™ pump and Bio-Dome™ Wound Dressing
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Ghent
for Upper Limb Soft Tissue Coverage
The Radial Forearm Flap In Reconstruction Of Upper Limb Injuries
The radial forearm flap is a very useful and versatile flap with a long vascular pedicle and a thin, pliable skin. It's used in reconstruction of the mutilated hand as a reverse pedicled flap.
- Trial name
- NCT06319586
- Testing
- Radial Forearm Flap
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post Traumatic Skin Loss
Negative Pressure Wound Therapy in Traumatic Skin Loss
Assessment of the effectiveness of negative pressure wound therapy on post-traumatic wounds, as regard to : The period of granulation tissue formation. The infection rate in NPWT in comparison to conventional dressing.
- Trial name
- NCT05653297
- Testing
- Vacuum-Assisted Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University
Finger Injury
Surgical Versus Conservative Treatment of Acute Mallet Fingers; a Randomised Controlled Trial
The investigators are investigating if surgical treatment of injuries to the tendon which straightens the finger tip gives a better functional outcome than treatment with a splint while the tendon heals.
- Trial name
- NCT01016197
- Testing
- extensor tendon repair, Mallet splint for 4 weeks
- Where
- United Kingdom
- Sponsor
- Mid Cheshire Hospitals NHS Foundation Trust
Emergencies, Infusion Site Injury
Soft Tissue and Bone Diameter in Children and Adults for Intraosseus Access
Retrospective observational study: Soft tissue and bone diameters are assessed in MRI and CT scans of patients. Data is compared with recommendations of intraosseus needle producers to assess whether the information provided by…
- Conditions
- Emergencies, Infusion Site Injury, Bone Infection
- Trial name
- NCT03082066
- Testing
- CT or MRI scan
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Medical University Innsbruck
Wounds and Injuries, War-Related Injuries
Wound Bacterial Microbiota and Their Antibiotic Resistance
The purpose of the study is to explore the microbiology in war-associated wounds of hospitalized patients from the Syrian armed conflict. Cultures collected from acute wounds with clinical signs of infection will be analyzed.
- Conditions
- Wounds and Injuries, War-Related Injuries, Wound Infection, Wounds, Penetrating
- Trial name
- NCT02744144
- Where
- Jordan
- Volunteers
- 457 people
- Sponsor
- Karolinska Institutet
Hip Dysplasia
Soft Tissue Pathology in Hip Dysplasia Before and After Periacetabular Osteotomy
Introduction: The lack of congruence between the acetabulum and femoral head in hip dysplasia compromise the passive stability of the hip joint resulting in increased stress on the acetabular labrum, joint capsule and the muscles…
- Trial name
- NCT02311166
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus