Clinical trials: Soft Tissue Injuries
Hand Injuries
Reconstruction of Hand Soft Tissue Defects
Evaluation of distally based posterior interosseous artery flap in reconstructing hand soft tissue defects that may result from trauma, extensive burns, tumor resection or congenital deformities.
- Trial name
- NCT05218252
- Testing
- Posterior interosseous artery flap
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Sohag University
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University
Concealed Penis
Surgical Repair of Pediatric Concealed Penis is Generally Safe and Efficacious. Criteria for Pediatric Concealed Penis Surgical Success Are Still Poorly Standardized, so Our Study Presents a Multi-dimensional Framework Consisting of Morphometric Measurements and Subjective Psychometric Parameters.
A concealed penis (CP) refers to a condition in which the normally-sized penis appears smaller or completely hidden in the prepubic area. Surgical repair of pediatric concealed penis is generally safe and efficacious.
- Trial name
- MPPPS SPL BPL (NCT07615439)
- Testing
- penoplasty by complete penile degloving to release all anomalous restrictive attachments, followed by phallopexy via proper fixation of the penile base
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Eslam Saad Hamza
Pediatric ALL, Surgery
Concealed Penis in Pediatric Age Group
Background: Comparison between three different surgical techniques in the management of concealed penis. Methods: This prospective interventional non-randomized study included 150 pediatric patients with concealed penis.
- Conditions
- Pediatric ALL, Surgery, Urologic Diseases
- Trial name
- NCT05565040
- Testing
- Circumcision in concealed penis
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Egyptian Biomedical Research Network
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Patella Dislocation
Outcome After Soft Tissue Realignment of the Tibial Insertion of the Patella Tendon
Soft tissue realignment of the tibial insertion of the patella tendon is a simple operative technique for treating dislocation of the patella in childhood and adolescence.
- Trial name
- NCT01059721
- Testing
- Medialising insertion of patella tendon
- Volunteers
- 43 people
- Sponsor
- Medical University of Graz
Traumatic Dental Injury, Tooth Aplasia
Premolar Autotransplantation in Juvenile Dentition: Quantitative Assessment of Vertical Bone and Soft Tissue Growth
Objective: Premolar autotransplantation represents an effective therapeutic option for the treatment of juvenile dentition in traumatic dental injury with tooth loss.
- Trial name
- NCT02740907
- Testing
- premolar autotransplantation
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- MKG-Praxisklinik
Open Wound of Lower Limb
Comparison of Distally Based Sural Artery and Supramalleolar Flap for Coverage of Dorsum of Foot and Ankle Defects
Our main aim for this study was to evaluate the long-term outcome comparisons between sural artery and Supramalleolar flap in the reconstruction of extensive defects of non-weight bearing regions of foot and ankle.
- Trial name
- NCT05027542
- Where
- Pakistan
- Volunteers
- 53 people
- Sponsor
- Abeer Musaddiq
Tennis Elbow
Mobilition With Movement and Soft Tissue Mobiiztion in Tennis Elbow
Lateral epicondylitis or tennis elbow is one of the most common lesions of the arm. This injury is a major challenge, as it is difficult to treat, prone to recurrence and may last for several weeks or months, with an average…
- Trial name
- NCT05039827
- Testing
- Mobilization with movement, Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Wounds and Injuries, War-Related Injuries
Wound Bacterial Microbiota and Their Antibiotic Resistance
The purpose of the study is to explore the microbiology in war-associated wounds of hospitalized patients from the Syrian armed conflict. Cultures collected from acute wounds with clinical signs of infection will be analyzed.
- Conditions
- Wounds and Injuries, War-Related Injuries, Wound Infection, Wounds, Penetrating
- Trial name
- NCT02744144
- Where
- Jordan
- Volunteers
- 457 people
- Sponsor
- Karolinska Institutet
Nerve Injury, Digital Pulp Defect
Free Dorsal Digital Flap for Reconstruction of Volar Soft Tissue Defect of Digits
The aim of the current report is to investigate the feasibility of transferring the free dorsal digital flap, including both dorsal branches of the proper digital nerves (PDNs), to reconstruct the volar soft tissue defect of…
- Trial name
- NCT01533337
- Testing
- Free dorsal digital flap
- Volunteers
- 12 people
- Sponsor
- The Second Hospital of Tangshan
Soft Tissue Inflammation
Prevention of Hypergranulation Tissue After Gastrostomy Tube Placement
The primary objective of this study is to compare the incidence of postoperative hypergranulation tissue formation after gastrostomy tube placement among children randomized to one of three treatments, in addition to measuring…
- Trial name
- NCT01501539
- Testing
- Standard Hydrocolloid Dressing, Silver Hydrocolloid Dressing
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Complex Digital Injuries
Reconstruction of a Neurocutaneous Defect of the Proximal Phalanx With a Heterodigital Arterialized Nerve Pedicle Flap
Complex digital injuries involving soft tissue loss and digital nerve defect pose challenging problems for hand surgeons. This study uses the heterodigital arterialized nerve pedicle flap including the dorsal branch of the…
- Trial name
- NCT01837407
- Testing
- Composite Flap
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Melanoma, Sarcoma
Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity
Hyperthermic isolated limb perfusion with melphalan alone is administered as a double perfusion schedule. These two isolates limb perfusions with melphalan are treated 3-6 weeks apart.
- Trial name
- NCT00001577
- Testing
- double isolated limb perfusion with melphalan alone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection
Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Abscess
The purpose of this study is to better understand why children develop methicillin-resistant Staphylococcus aureus (MRSA) skin infections that require surgical drainage and whether antibiotics are helpful after the infection is…
- Conditions
- Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection, Skin Abscess
- Trial name
- NCT01498744
- Testing
- Oral Clindamycin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Wounds
Negative Pressure Wound Therapy With the Engenex™-Pump and Bio-Dome™ Dressing, an Evaluation
Negative pressure wound therapy (NPWT) has become a powerful tool in wound bed preparation of complex wounds and is routinely used in various disciplines, including general surgery and plastic surgery.
- Trial name
- NCT01107821
- Testing
- Engenex™ pump and Bio-Dome™ Wound Dressing
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Ghent
Fractures, Bone
Effect of Instrument Assisted Soft Tissue Mobilization and Dynamic Cupping
Children who experience fractures may develop stiffness and limited range of motion in their affected joints, notably the elbow.
- Trial name
- NCT06673745
- Testing
- IASTM, Dynamic cupping therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Femur Fracture
Titanium Elastic Nails in the Treatment of Pediatric Femur Fractures
Titanium elastic nails in the pediatric femoral fractures: A prospective randomized clinical trial of eliminating nail protrusion to decrease soft tissue complications
- Trial name
- NCT00175656
- Testing
- Elimination of titanium elastic nail prominence at the insertion site and leaving the nails in situ
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Soft Tissue Injuries
Cost-effectiveness of Two Painkillers for Treating Pain After Limb Injuries
Background: Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are commonly used oral analgesics in emergency departments (ED) not only in Hong Kong but throughout the world.
- Trial name
- NCT00528658
- Testing
- Paracetamol, Ibuprofen
- Where
- Hong Kong
- Volunteers
- 782 people
- Sponsor
- Chinese University of Hong Kong
Sarcoma, Wound Infection
Negative Pressure Dressing Therapy in Soft Tissue Sarcoma Surgery
This randomised controlled trial aims to evaluate the difference in surgical site infection following excision of soft tissue sarcomas.
- Trial name
- NCT02901405
- Testing
- Negative Pressure Wound Therapy (ActivVAC, KCI), Standard dressings
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- NHS Greater Glasgow and Clyde