Clinical trials: Spectrum
Autism Spectrum Disorder
Effect of Omega-3 Fatty Acid on Neurobehavioral Status of Children With Autism Spectrum Disorder: A Randomized, Double-Blind, Placebo Controlled Trial
This study is conducted to assess whether Omega-3 fatty acid improves neurobehavioral staus of children with Autism Spectrum Disorder and whether there is any correlation of this improvement with reference range of Omega-3 fatty…
- Trial name
- NCT06125782
- Testing
- Omega 3 fatty acid
- Where
- Bangladesh
- Volunteers
- 64 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Autism Spectrum Disorder (ASD)
Pilot-RCT With Individualized Homeopathic Treatment in the Children With Autism Spectrum Disorder
This study looked at whether homeopathic treatment could help children with Autism Spectrum Disorder (ASD) when used alongside regular therapies like speech and occupational therapy.
- Trial name
- Pilot-RCT ASD (NCT07054697)
- Testing
- Homoeopathic medicines, THERAPY
- Where
- India
- Volunteers
- 54 people
- Sponsor
- Aditi Chadha
Autism Spectrum Disorder, Intellectual Disability
Heart Rate Informed Changes in Care for Non-Communicating Patients
The overarching aim is to generate knowledge to reduce incidence of pain in non-verbal patients' everyday life. The trial will 1) evaluate how HR can be used to identify potentially painful care procedures that should be…
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Communication, Nonverbal
- Trial name
- NCT05738278
- Testing
- HR-informed change in routine, Delayed HR-informed specific change in routine
- Where
- 2 sites in Norway
- Volunteers
- 38 people
- Sponsor
- University of Oslo
Autism Spectrum Disorder
ABC-CT Pre-School Feasibility Study
This is a multicenter study that aims to determine whether the EEG and ET experiments studied in the ABC-CT Phase 1 and ABC-CT Confirmation studies can be successfully used with 3-5-year-old children and to determine the…
- Trial name
- NCT06413316
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Autism Spectrum Disorders
Intestinal Permeability in Children With Autism Spectrum Disorder
In recent years, increasing attention has been directed toward the role of the gut-brain axis in the pathogenesis of neurodevelopmental disorders, particularly Autism Spectrum Disorder (ASD).
- Trial name
- IP-ASD (NCT07032857)
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- University of Bari
Autism Spectrum Disorder, Autism Spectrum Disorder With Absence of Functional Language
Aut-CARE Intervention to Improve Cognitive and Emotional Functioning in Young Adults on the Autism Spectrum
Currently, many autistic youths struggle to adapt to academic programs or the workforce, often turning to third-sector organizations such as specialized associations and foundations.
- Trial name
- Aut-CARE (NCT07041502)
- Testing
- Aut-CARE
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Autism Spectrum Disorder, Anxiety
Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities
The goal of this clinical trial is to investigate neural constructs related to anxiety symptoms in response to Facing Your Fears (FYF) treatment in autistic participants with co-occurring anxiety.
- Trial name
- IAA (NCT06904508)
- Testing
- Facing Your Fears (FYF) Intervention: A CBT Focused Group Treatment for Autistic Youth with Anxiety
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Montclair State University
Autism Spectrum Disorder
A Virtual Dental Office Experience for Children With Autism Spectrum Disorder
The objective of this study is to evaluate the effectiveness of virtual reality (360° video) compared to a social story for reducing pre-visit dental anxiety for children with autism spectrum disorder (ASD) improve the dental…
- Trial name
- NCT05196230
- Testing
- Control Condition (Social Story), Experimental Condition (360° Video)
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
PIK3CA-related Overgrowth Spectrum
Health-related Quality of Life, Symptom Severity, and Pain Among Patients With PIK3CA-related Overgrowth Spectrum: A Mixed-methods Observational Study
This was a mixed-methods observational study that incorporated both qualitative interviews and longitudinal quantitative data collection through an online survey (initial, 2 months, and 4 months).
- Trial name
- NCT05294289
- Testing
- Alpelisib
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Novartis Pharmaceuticals
Autism Spectrum Disorder
Sleep, Mood, and Quality of Life Issues in ASD Adolescents and Adults.
Autism Spectrum Disorder (ASD) presents unique challenges, particularly in sleep, mood, and quality of life for adolescents and adults.
- Trial name
- NCT07033078
- Where
- Taiwan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Neuromyelitis Optica Spectrum Disorder (NMOSD)
Efficacy and Safety of Conventional Immunosuppressant Therapies in Elderly Patients With Neuromyelitis Optica Spectrum Disorder
Newly diagnosed NMOSD patients
- Trial name
- NCT07032337
- Volunteers
- 2,985 people
- Sponsor
- Samsung Medical Center
Challenging Behavior, Autism Spectrum Disorder
Measurement of Treatment Effects
The overall objective is to evaluate and compare the efficacy of two common treatments for CB in children and adolescents with autism using multiple outcome measures.
- Trial name
- NCT07024303
- Testing
- Psychotropic medication (at discretion of psychiatrist), Behavioral therapy
- Volunteers
- 20 people
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
Autism, Autism Spectrum Disorder (ASD)
Evaluation of the Social ABCs in Israel
The goal of this study is to evaluate the effectiveness of the Social ABCs program for young autistic children and their parents. The study will also explore predictors of treatment success and child outcomes.
- Trial name
- NCT07025603
- Testing
- The social ABCs
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Hebrew University of Jerusalem
Autism Spectrum Disorder, Neurodevelopmental Disorders
Early Detection and Referral for Autism and Neurodevelopmental Disorders at the Maternal and Child Protection Services
This study aims to compare two screening strategies for identifying infants with a potential risk of Autism Spectrum and Neurodevelopmental Disorders to provide early access to care and increase the likelihood of a favorable…
- Trial name
- NCT05815095
- Testing
- PREAUT grid
- Where
- France
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Autism Spectrum Disorder
The Validation and Biological Index Studies on the Improved Social Function of ASD by 40 Hz tACS
In this proposed study, tACS will be used to intervene in the autism spectrum disorders of children and adolescents, and the efficacy of this intervention method will be evaluated, as well as the internal mechanism of…
- Trial name
- NCT06362200
- Testing
- 40 Hz tACS intervention
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Central South University
Autism Spectrum Disorder, Autism
Vancomycin and Fecal Microbiota Transplant in a Single Patient With Autism Spectrum Disorder
Single patient with ASD will be treated with Vancomycin followed by FMT.
- Trial name
- NCT04878718
- Testing
- Fecal Microbiota Transplant; Vancomycin
- Where
- United States
- Sponsor
- ProgenaBiome
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Autism, Autism Spectrum Disorder
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Autism
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding autism.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Autism, Akinetic
- Trial name
- NCT04100863
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Autism Spectrum Disorder, Developmental Disability
Propranolol for Challenging Behaviors in Autism
Severe challenging behaviors such as aggression and self-injury can cause significant morbidity and decrease the quality of life for individuals with Autism Spectrum Disorders (ASD).
- Conditions
- Autism Spectrum Disorder, Developmental Disability, Aggression, Self-Injurious Behavior
- Trial name
- NCT04047355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Therapeutic Impacts of Theta Burst Stimulation Over Bilateral Posterior Superior Temporal Sulcus in Autism Spectrum Disorder
The investigator would like to investigate the impact of intermittent theta burst stimulation over bilateral posterior superior temporal sulcus in autism spectrum disorder
- Trial name
- NCT05578209
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital