Clinical trials: Spectrum
Cerebral Palsy, Muscular Dystrophies
Turkish Version of The Measure of Processes of Care (MPOC)
Family-centred care (FCS) is considered the best practice in providing rehabilitation to children with disabilities and special needs.
- Conditions
- Cerebral Palsy, Muscular Dystrophies, Autism Spectrum Disorder, Traumatic Brain Injury
- Trial name
- NCT03508583
- Testing
- Participation
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Autism Spectrum Disorder, Parents
Clinicianless Training in Autism Treatment: An Adaptive Online Parent Education Program
This project will examine the feasibility, acceptability, and preliminary efficacy of using a smartphone app-based parent training program focused on early autism intervention strategies.
- Trial name
- NCT04992169
- Testing
- Smartphone-App Parent Training in Pivotal Response Treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of California, Santa Barbara
Autism Spectrum Disorders
Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorders
Determine if riluzole shows evidence of efficacy, safety, and tolerability targeting drug-refractory irritability (DRI) in persons with autism spectrum disorders (ASD).
- Trial name
- NCT02081027
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pediatric Bipolar Spectrum Disorders
Inositol and Omega-3 Fatty Acids in Pediatric Mania
The purpose of this study is to a) evaluate the efficacy of omega-3 fatty acids versus inositol in the treatment of pediatric bipolar disorder, b) evaluate the efficacy of omega-3 fatty acid plus inositol in the treatment of…
- Trial name
- NCT01396486
- Testing
- Omega-3, Inositol
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Schizophrenia
Cognitive Enhancement Therapy for Early-Stage Schizophrenia
This study will determine the effectiveness of cognitive enhancement therapy (CET) in treating cognitive abnormalities in people experiencing the early stages of schizophrenia.
- Trial name
- NCT00167362
- Testing
- Cognitive enhancement therapy (CET), Enriched supportive therapy (EST)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Schizophrenia, Bipolar I Disorder
Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I Disorder
The purpose of this study is to demonstrate the efficacy and safety of quetiapine fumarate (SEROQUEL) in the treatment of adolescent patients with schizophrenia and bipolar I disorder.
- Trial name
- ANCHOR 150 (NCT00227305)
- Testing
- quetiapine fumarate
- Where
- 48 sites in United States, India and 7 more
- Volunteers
- 381 people
- Sponsor
- AstraZeneca
PCOS
Eye Evaluation in Patients With PCOS
To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in polycystic ovary syndrome (PCOS) and to compare them with healthy…
- Trial name
- NCT01950832
- Testing
- Investigating clinically normal patients with optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Gökhan Açmaz
Autism Spectrum Disorder
The Therapeutic Effects of Intermittent Theta Burst Stimulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of theta burst stimulation over right inferior frontal gyrus in autism spectrum disorder
- Trial name
- NCT04987749
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Bipolar Disorder, Schizophrenia
Clinical Risk State for Bipolar Disorder in Adolescents
Aim: The purpose of the study is to characterize the at-risk phases preceding a first episode of bipolar disorder and of schizophrenia, and to identify clinical and biological predictors of the disease development.
- Trial name
- NCT01383915
- Where
- United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Cognition
Effects of Hyperbaric Oxygen Therapy on Cognitive Function on Autistic Spectrum Disordered Children
HYPOTHESIS 1. Hyperbaric Oxygenation Therapy will be safe to use with neurotypical adults and children. 2. Hyperbaric Oxygenation Therapy will have a statistically significant positive effect on measures of cognitive function in…
- Trial name
- NCT00631215
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pediatric Partners of Ponte Vedra
Autism Spectrum Disorder
Investigation of Brain Plasticity in Autism Spectrum Disorders
Individuals with autism spectrum disorders (ASD) commonly experience variances in tactile behaviors, such as hypersensitivity to light touch stimuli, altered texture discrimination, and hyporesponsivity to pain.
- Trial name
- NCT04706364
- Testing
- Neuropsychological Testing, (Optional) Saliva Collection, Sensory Testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism Disorder
TRIal of PPF3 vs. PlaCEbo in the TReatment of Children and AdolescenTs With NeurOdeveloPmental DisorderS
A Randomized Placebo-Controlled TRIal of PPF3 vs. PlaCEbo in the TReatment of children and AdolescenTs with NeurOdeveloPmental DisorderS
- Trial name
- TRICERATOPS (NCT07893964)
- Testing
- PPF3
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autistic Disorder
Comparison of Applied Behavioral Analysis (ABA) Versus ABA and Risperidone
Hypotheses: 1. Preschool children with autism spectrum disorders (ASDs) who undergo ABA treatment only will demonstrate significantly better outcomes compared to an age and severity matched control group without ABA treatment. 2.
- Trial name
- NCT00374764
- Testing
- Risperidone, ABA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Autism Spectrum Disorder, High-functioning Autism
Effects of Transcranial Pulse Stimulation on ASD
The aim of this study is to evaluate the efficacy and tolerability of TPS on young adolescents with ASD. Methods: This is a two-armed, randomized, double-blinded, sham-controlled trial.
- Trial name
- NCT05408793
- Testing
- Transcranial Pulse Stimulation
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia, Schizoaffective Disorder
Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis
This study will assess the effectiveness of an experimental treatment intervention for adolescents and adults who have experienced their first episode of psychosis during the past two years.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder
- Trial name
- NCT01216891
- Testing
- Multi-element, team-oriented treatment
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Autism Spectrum Disorder, Early Developmental Impairment
Multicenter Validation Study on Autism Screening Using a Machine-assisted System
The goal of this observational study is to assess the effectiveness of a machine-assisted system for early screening of autism. The main questions it aims to answer are: Does the machine-assisted system including 5 main…
- Conditions
- Autism Spectrum Disorder, Early Developmental Impairment, Language Development Disorders
- Trial name
- NCT07006948
- Testing
- Autism Diagnostic Observation Schedule, the 2nd edition(ADOS-2), Griffiths Developmental Scales, Chinese edition(GDS-C)
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism, Autism Spectrum Disorder
Improving Academic and Social Functioning in Middle-Schoolers With Autism
The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT06705907
- Testing
- Achieving Independence and Mastery in School (AIMS), Building Essential Social Skills for Teens (BESST)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Schizophrenia, Bipolar
Bipolar and Schizophrenia Consortium for Parsing Intermediate Phenotypes
Briefly, this multisite study is designed to identify endophenotypes (i.e., heritable biomarkers) associated with either schizophrenia or bipolar disorder alone, or both together.
- Trial name
- NCT00666432
- Testing
- This is an observational study model that is family based
- Where
- 6 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
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