Clinical trials: Spinal Injuries
Neuromuscular Disorders, Neurodevelopmental Disorders
Safety, Usability, and Effectiveness of a Gait Exoskeleton for Children and Adolescents With Neurodevelopmental Disorders.
Neurodevelopmental disorders often result in abnormal development of the Central Nervous System (CNS), frequently causing motor dysfunctions such as the inability to stand and walk.
- Trial name
- NCT07159360
- Testing
- CLINICAL EXPLORER
- Where
- 2 sites in Mexico, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MarsiBionics
Spinal Cord Injury
Medico-legality of Acute Spinal Cord Injuries
1. Describe different medico-legal aspects of TSI (mode of trauma, cause and Pattern of spinal injuries). 2. Assess the outcome of TSI in studied cases. 3.
- Trial name
- NCT06717503
- Testing
- data collection
- Volunteers
- 120 people
- Sponsor
- Assiut University
Spinal Cord Injuries, Neuropathic Pain
Evaluation of Initiation Time on the Efficacy of Gabapentin in Treating Neuropathic Pain in SCI
Neuropathic pain is a common complaint in those with spinal cord injury (SCI) that has a significant negative effect on quality of life. Efficacy of various treatments, however, remains controversial.
- Trial name
- NCT04256603
- Testing
- Gabapentin, No gabapentin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- MetroHealth Medical Center
Spinal Cord Injury
Autologous Mesenchymal Stem Cells in Spinal Cord Injury (SCI) Patients
The aim of this study is to evaluate the use of autologous expanded mesenchymal stem cells intralesional transplantation as a safe and potentially beneficial treatment for patients with spinal cord injury.
- Trial name
- MSC-SCI (NCT01694927)
- Testing
- Autologous Mesenchymal Stem Cells
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Clínica Las Condes. LIT INNOVA CORFO
Spinal Cord Injury, Stroke
Interactive Motor Imagery in Virtual Reality
This project will build and test the first rehabilitation system employing virtual reality (VR)-based observation, motor imagery and execution to treat lower-limb neuropathic pain and motor dysfunction in participants with an…
- Trial name
- NCT02149186
- Testing
- iCTuS-L
- Where
- Switzerland
- Volunteers
- 79 people
- Sponsor
- University of Zurich
Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS)
Control of Assistive Devices Via Brain-Computer Interface Technology
The CONVOY Study is a clinical trial designed to explore the feasibility of participants from the PRIME Study (NCT06429735) using the N1 Implant to control various assistive devices.
- Conditions
- Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS), Quadriplegia, Spinal Cord Injury (SCI)
- Trial name
- CONVOY (NCT06710626)
- Testing
- Assistive Robotic Arm
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Neuralink Corp
Spinal Cord Injuries, Neurogenic Bladder
Pediatric Locomotor Training Bladder Study
Bladder dysfunction is one of the most important factors influencing duration and quality of life in children with spinal cord injury.
- Trial name
- NCT03559036
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Spinal Cord Injury
Functional Electrical Stimulation (FES) Cycling for Children With Spinal Cord Injuries (SCI)
The overall objective of this research project is to examine the clinical efficacy of lower extremity cycling with functional electrical stimulation to improve the health and fitness of children with spinal cord injuries (SCI).
- Trial name
- NCT00245726
- Testing
- FES Cycle, ES therapy, Passive (Motor Assist) Cycle
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Shriners Hospitals for Children
Spinal Cord Injury at C5-C7 Level, Spinal Cord Injuries
Grasp-Release Assessment of a Networked Neuroprosthesis Device
The overall objective of this trial is to characterize the safety and effectiveness of the Networked Neuroprosthesis Device - Upper Extremity (NP-UE) in individuals living with cervical SCI.
- Conditions
- Spinal Cord Injury at C5-C7 Level, Spinal Cord Injuries, Spinal Cord Injury Cervical
- Trial name
- GRANND (NCT05863754)
- Testing
- Networked Neuroprosthesis Device
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- MetroHealth Medical Center
Cervical Spinal Cord Injury
Laminectomy Alone Versus Laminectomy and Fusion for Traumatic Cervical Spinal Cord Injury Without Instability
The aim of study is to compare clinical and radiological outcomes of laminectomy alone to laminectomy and fusion in the treatment of traumatic cervical spinal cord injury without instability.
- Trial name
- NCT05360524
- Testing
- Laminectomy alone versus laminectomy and fusion
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Spinal Cord Injury
Large Language Models for Epidural Stimulation Electrode Mapping in Spinal Cord Injury
This observational and methodological study aims to compare the performance of large language models in generating electrode contact configuration recommendations for epidural electrical stimulation in spinal cord injury.
- Trial name
- NCT07817238
- Testing
- ChatGPT-4o Large Language Model, Claude Large Language Model, Grok 3 Large Language Model
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Gelisim University
Spinal Cord Injury
Daily-life Brain Control Of A Hand Exoskeleton After Cervical Spinal Cord Injury
In this study, 6 volunteer participants with chronic spinal cord injury will be invited to use an autonomous hand exoskeleton device controlled by a brain/neural-computer interaction (BNCI) system fusing electroencephalography…
- Trial name
- NCT02336321
- Testing
- BNCI controlled hand exoskeleton
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- University Hospital Tuebingen
Spinal Cord Injury
A Scar Recognition Software for Chronic Spinal Cord Injury (SCI)
To construct and validate a software to recognize scar for patients with chronic SCI based on multimodal MRI.
- Trial name
- NCT04955509
- Testing
- MRI
- Volunteers
- 25 people
- Sponsor
- Peking University Third Hospital
Spinal Cord Injury
The Effect of FES on Children With Spinal Cord Injury
Regular exercise is strongly recommended to help maintain a healthy lifestyle. Unfortunately, children and young adults with damaged spinal cords may not be able to exercise regularly.
- Trial name
- NCT00291317
- Testing
- RT 300-P FES Cycle
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Specialized Hospital
Acute Spinal Cord Injury, Spinal Cord Injuries
Safety, Feasibility, and Efficacy of TSCS on Stabilizing Blood Pressure for Acute Inpatients With SCI
Current forms of pharmacologic and non-pharmacologic treatments for hypotension and orthostatic hypotension (OH) remain inadequate during acute inpatient rehabilitation (AIR) following a traumatic spinal cord injury (SCI).
- Conditions
- Acute Spinal Cord Injury, Spinal Cord Injuries, Neuromodulation, Traumatic Spinal Cord Injury
- Trial name
- NCT06000592
- Testing
- Digitimer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jill M. Wecht, Ed.D.
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Spinal Cord Injury
The Effect of an Exercise Program on Physical Function After a Spinal Cord Injury
This study would focus on adding a group exercise program to the usual therapy delivered in the hospital. We propose to design an exercise program that would be 30 minutes in length, 3 times per week.
- Trial name
- NCT00535210
- Testing
- Cardiovascular training, Balance training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Spinal Cord Injuries, Pain, Chronic
Hypnotic Cognitive Therapy Reduce Acute & Chronic SCI Pain in Inpatient Rehabilitation
Chronic spinal cord injury (SCI) pain is complex and difficult to treat. For individuals with SCI, pain often begins early in the course of their SCI and continues longitudinally.
- Conditions
- Spinal Cord Injuries, Pain, Chronic, Spinal Cord Injury, Acute
- Trial name
- HYPCT (NCT05047120)
- Testing
- Hypnosis enhanced cognitive behavioral therapy, Pain Education
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Washington
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Traumatic Injury of the Spinal Cord
Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Hypothesis of the Study: Based on the presented results, the investigator hypothesises that HBO preserves neurons that are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of their function.
- Trial name
- NCT03101982
- Testing
- HBO
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Graz