Clinical trials: Substance Use Disorder
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Drug Addiction
Survey of Buprenorphine Use Among "Out of Care" Population in France (P04933)(COMPLETED)
This study was a survey of drug users who obtain buprenorphine from the black market and have used buprenorphine during the last month.
- Trial name
- NCT00756353
- Volunteers
- 600 people
- Sponsor
- Indivior Inc.
Substance Use Disorders
Measurement Training and Feedback System: Family-Based Services
National mandates for increasing accountability in behavioral healthcare have created an urgent need for effective quality assurance (QA) procedures featuring pragmatic measures of treatment implementation quality in usual care…
- Trial name
- MTFS-FBS (NCT03342872)
- Testing
- Core Training: FBS System Mapping and MTFS-I Installation, Core Training & Facilitation: FBS System Mapping and MTFS-I Installation plus monthly on-site meetings
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
HIV, Hepatitis C
Ending Transmission of HIV, HCV, and STDs and Overdose in Rural Communities of People Who Inject Drugs (ETHIC)
This study will evaluate the referral to harm reduction services (HRS) including syringe services, naloxone overdose prevention, substance use treatment referral, HIV, HCV, and STD testing and referral and linkage to care through…
- Conditions
- HIV, Hepatitis C, Opioid-use Disorder, Injection Drug Use
- Trial name
- ETHIC (NCT04427202)
- Testing
- Referral to harm reduction services
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- University of Chicago
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Substance-related Disorders
Project CHOICE: Efficacy Testing of CHOICE and CHOICE+Normative Feedback Interventions
This study will use a pilot test format to examine the efficacy of a brief Motivational Interviewing (MI) intervention developed by the investigator Dr.
- Trial name
- CHOICE (NCT02083523)
- Testing
- Motivational Interview with Normative Feedback, Motivational Interview
- Volunteers
- 48 people
- Sponsor
- University of Illinois at Urbana-Champaign
Cannabis Use Disorder
CANDIS - Targeted Treatment for Cannabis Disorders
The purpose of this study is to develop a modular treatment program for cannabis use disorders and the evaluation of the effectiveness in a controlled clinical study.
- Trial name
- NCT00252980
- Testing
- Psychotherapy
- Where
- Germany
- Volunteers
- 210 people
- Sponsor
- Technische Universität Dresden
Perinatal Opioid Use Disorder, Opioid Use Disorder
Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT
To address both loneliness and engagement in perinatal and OUD care among perinatal women, the investigators plan to adapt an existing texting support chatbot, Penny, to make it appropriate for use by women who are pregnant and…
- Trial name
- PENNY-COPILOT (NCT06969261)
- Testing
- Penny COPILOT
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Tobacco Dependence
Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking
The purpose of this study is to determine: 1) the short-term clinical efficacy and safety of bupropion for helping adolescent tobacco smokers quit, and 2) The role of withdrawal symptoms in the maintenance of smoking in…
- Trial name
- NCT00248118
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Substance Use, Harm Reduction
A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
The primary goal of this study is to test the effectiveness of the iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment) curriculum, a novel drug education and diversion program, in approximately 300…
- Conditions
- Substance Use, Harm Reduction, Adolescent Behavior
- Trial name
- NCT06115746
- Testing
- iDECIDE
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Substance Use
Mindfulness-Based Substance Use Prevention (MINDS-UP)
The goal of this clinical trial is to test the feasibility, behavioral/neural mechanisms, and preliminary efficacy of "MINDfulness-based Substance Use Prevention Program," or "MINDS-UP", a novel substance use prevention…
- Trial name
- MINDS-UP (NCT06593470)
- Testing
- MINDS-UP, Prevention Plus Wellness
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Substance Use, Mental Health Issue
Adolescent Screening and Personalized Intervention Resource for Enhancement of Behavioral Health and Substance Use
Only a small fraction of youth who are beginning to experience behavioral health problems and use alcohol or illicit drugs receive needed treatment services due to the lack of accessible, effective early intervention resources.
- Trial name
- ASPIRE (NCT06306287)
- Testing
- ePACE Personalized Intervention, eFACE Fixed Intervention
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Cannabis Use Disorder
Teen Marijuana Check-Up
This study will test a behavioral intervention tailored for adolescents who smoke marijuana and have concerns about their use. The study's purpose is to determine whether this intervention (two-sessions of motivational…
- Trial name
- NCT01109563
- Testing
- Marijuana Check-Ins
- Volunteers
- 252 people
- Sponsor
- Denise Walker
Opioid Use Disorder
EMS-Initiated Buprenorphine
This is a multisite EMS study that will first conduct a sequence of pragmatic, prehospital field studies to provide preliminary feasibility, acceptability, and safety data for refinement and enhancement of a subsequent single-arm…
- Trial name
- EMS BUP (NCT07475728)
- Where
- 3 sites in United States
- Volunteers
- 495 people
- Sponsor
- Yale University
Binge Drinking, Problematic AOD Use
Two Consecutive Randomized Controlled Trials Using Mobile Phone Applications for Risky Alcohol Use
The purpose of this study is to evaluate the efficacy of three mobile phone applications, Promillekoll, PartyPlanner and TeleCoach among university student union members with problematic drinking.
- Trial name
- NCT02064998
- Testing
- Promillekoll, PartyPlanner, TeleCoach
- Where
- Sweden
- Volunteers
- 2,166 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Opioid Related Disorders, Opiate Addiction
Evaluation of Drug Utilization Patterns for Extended Release/Long Acting Opioids and Comparator Products
A drug utilization study will be performed to describe trends in the number of prescriptions and patients for class REMS ER/LA opioids and comparator products.
- Conditions
- Opioid Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02925806
- Testing
- Non-interventional study - retrospective database review
- Volunteers
- 5,575,834 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Opioid-use Disorder
Evaluation of Long-term Buprenorphine Plasma Exposure
The study objective is to characterise the long-term plasma exposure to buprenorphine after stopping SUBLOCADE treatment. There are no interventions planned.
- Trial name
- NCT03752528
- Testing
- Blood sample collection, Urine sample collection
- Where
- 11 sites in United States
- Volunteers
- 53 people
- Sponsor
- Indivior Inc.
Child Behavior, Parent-Child Relations
A Scaleable Video Coaching Intervention for Opioid-using Mothers
This study will adapt and evaluate a novel, innovative, and highly scalable parenting intervention that employs video coaching to target responsive parenting, Filming Interactions to Nurture Development (FIND), among women who…
- Conditions
- Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
- Trial name
- NCT04749771
- Testing
- Filming Interactions to Nurture Development, The Healthy Toddler Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Oregon
Substance Use, Self Esteem
Native Spirit: Significant Aim 3: Intervention
The proposed research will used community-based participatory research methods in an urban-based American Indian (AI) community to adapt, implement, and evaluate an after-school program, called Native Spirit (NS), that seeks to…
- Conditions
- Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
- Trial name
- NCT06785311
- Testing
- Native Spirit After-School Program
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cannabis Use, Cannabis Dependence
Neuroimaging of Adolescent Cannabis Use Treatment
This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use.
- Conditions
- Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse
- Trial name
- ACT (NCT07340554)
- Testing
- Contingency Management, Elastic Net Regression
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University