Clinical trials: Surgery of Breast Cancer
Breast Cancer
Cosmetic and Functional Outcomes After Breast Conserving Surgery
The initial aesthetic and functional conditions are recorded with the help of the Breast Cancer Treatment Outcome Scale (BCTOS),an international validated questionnaire, and the Breast Cancer Conservative Treatment - cosmetic…
- Trial name
- NCT01496001
- Testing
- Lumpectomy, axillary block dissection, breast conserving surgery, Radiotherapy
- Where
- Hungary
- Volunteers
- 300 people
- Sponsor
- National Institute of Oncology, Hungary
Breast Cancer, Right or Left Breast Mammary Reconstruction
Psycho-esthetic Impact of Tattoo Technology as Part of Mammary Reconstruction After Surgery Against Breast Cancer
Mammary reconstruction replaces total skin transplant, which may causing patient discomfort. It is a simple, painless and reproductible technology that avoids consequences and complications related to transplant.
- Conditions
- Breast Cancer, Right or Left Breast Mammary Reconstruction, Malignant Neoplasm Reconstruction by Tattoo of Areola of Female Breast
- Trial name
- NCT02464982
- Testing
- Tattoo
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer
Accessory Joint and Neural Mobilizations in Shoulder After Breast Cancer Surgery. Randomized Clinical Trial.
The potential consequences after breast cancer surgery are joint pain and sensitive disorders, the main sign of which is alterations in shoulder mobility.
- Trial name
- NCT02366793
- Testing
- Accessory joint mobilization, Nerve mobilization
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Breast Cancer, Chemotherapy Effect
Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Introduction: Neoadjuvant chemotherapy (NACT) has been the standard therapy for treating patients with locally advanced breast cancer (LABC). Doxorubicin-based regimen showed a clinical response for 70-80%.
- Trial name
- NCT04418089
- Testing
- Simvastatin 40mg
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Breast Neoplasms
A Prospective Study of Preoperative Tumor-bed Boost Followed by Oncoplastic Surgery and Adjuvant Whole Breast Radiotherapy for Early Stage Breast Cancer (BIRKIN)
This study explores the feasibility of preoperative single-dose tumor-bed boost followed by oncoplastic breast-conserving surgery and ultra-hypofractionated postoperative radiotherapy in patients with early stage breast cancer.
- Trial name
- BIRKIN (NCT05603078)
- Testing
- Preoperative MRI-guided tumor-bed boost and postopreative ultra-hypofractionated radiotherapy (26 Gy/5.2Gy/5)
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Breast Cancer
Radiation Therapy in Treating Women Who Have Undergone Surgery for Early-Stage Invasive Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Radiation to the tumor site and surrounding area may kill more tumor cells.
- Trial name
- NCT00005957
- Testing
- Standard Breast Irradiation, Breast Radiation plus Regional Radiation
- Where
- 26 sites in Canada
- Volunteers
- 1,832 people
- Sponsor
- NCIC Clinical Trials Group
Stroke, Transient Ischemic Attack
The "COSMOS"-Study (Copeptin in Osmoregulation and Stress Assessment)
Sodium imbalance is common and an adverse prognostic factor in hospitalized patients. However, identifying the causes of sodium imbalance is challenging in clinical practice.
- Trial name
- NCT00390962
- Where
- Switzerland
- Volunteers
- 469 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer, Breast Neoplasms
Trends of Mastectomy and Breast-Conserving Surgery in Female Breast Cancer Patients
Breast cancer is the most common cancer in women across the world, accounting for 25.2% of cancer cases among females and 14.7% of cancer-related deaths among females worldwide.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Cancer Female
- Trial name
- NCT03762642
- Testing
- Mastectomy, Breast-Conserving Surgery
- Where
- Saudi Arabia
- Volunteers
- 335 people
- Sponsor
- King Abdulaziz University
Breast Cancer
Comparison of MRI and CEDM to Evaluate Treatment Response Before Surgery
The purpose of this study is to compare the diagnostic accuracy of breast magnetic resonance imaging (MRI) and contrast enhanced digital mammography (CEDM) in assessing the residual disease extent in patients who have completed…
- Trial name
- NCT03070340
- Testing
- Breast Magnetic Resonance Imaging (MRI), Contrast Enhanced Mammography (CEDM)
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lymphedema of Upper Arm
Study of the Change of Breast Cancer Patients' Upper Limb Lymphatic Drainage Pathway After Operation
Lymphoscintigraphy is a noninvasive，accurate and effective imaging modality. In this study, it is used to investigate the imaging characteristics of patients'upper limb lymphatic drainage before operation, and the influence of…
- Trial name
- NCT02691624
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Breast Cancer, Modified Radical Mastectomy
Use of Harmonic in Breast Surgery
To compare harmonic scalpel with electrocautery for outcomes i.e. estimated blood loss (EBL), operating time, drain Volume and drain Days, seroma formation, surgical site infection and postoperative pain in adult females…
- Trial name
- HMRM (NCT01587248)
- Testing
- Harmonic, electrocautery
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Aga Khan University
Breast Cancer
Cryosurgery in Treating Women With Breast Lesions
RATIONALE: Cryosurgery kills cancer cells by freezing them. Cryosurgery followed by lumpectomy or mastectomy may be an effective treatment for breast lesions.
- Trial name
- NCT00020852
- Testing
- conventional surgery, cryosurgery
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer
Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer
RATIONALE: Collecting samples of blood and tissue from patients with cancer to study in the laboratory may help doctors learn how fluvastatin effects biomarkers related to breast cancer.
- Trial name
- NCT00416403
- Testing
- fluvastatin sodium, Breast Cancer Surgery Only - Arm III
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Pegylated Liposomal Doxorubicin and Docetaxel in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00524459
- Testing
- docetaxel, pegylated liposomal doxorubicin hydrochloride, conventional surgery
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Roswell Park Cancer Institute
Breast Cancer
Preoperative Breast Magnetic Resonance Imaging for Patients Undergoing Mammoplasty
all female with operable breast cancer seeking health care at general surgery department Assiut university hospitals,and decision of therapeutic mammoplasty was taken depending on clinical examination, findings on mammography and…
- Trial name
- NCT03173469
- Testing
- magnetic resonance imaging of breast
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Breast Cancer
Anti-tumour Effects & Tolerability of Faslodex Alone or in Combination With Arimidex in Post Menopausal Women Prior to Surgery for Primary Breast Cancer
To compare the anti-tumour effects as measured by changes in various biomarkers, of a combination of Faslodex and Arimidex with Faslodex alone and Arimidex alone in postmenopausal women patients with primary breast cancer who are…
- Trial name
- NCT00259090
- Testing
- Fulvestrant, Anastrazole
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Breast Cancer
Collecting Tissue Samples for Future Research From Women Undergoing Surgery for Breast Cancer
RATIONALE: Collecting and storing samples of tumor tissue from patients with breast cancer to study in the laboratory may help doctors learn more about cancer.
- Trial name
- NCT00898131
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Northwestern University
Breast Cancer
Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as epirubicin, cyclophosphamide, paclitaxel, and gemcitabine use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00070278
- Testing
- cyclophosphamide, epirubicin hydrochloride, gemcitabine hydrochloride
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Cancer, Fatigue
Cancer Patients' Knowledge About Fatigue
Background: Result from an earlier study I carried out in the late 1990 showed that cancer patients were overall well informed about diagnoses, prognoses, symptoms, treatment, side-effects of treatment e.g.
- Trial name
- NCT00927433
- Testing
- Psychoeducational intervention for cancer-related fatigue
- Volunteers
- 160 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Positron Emission Tomography Before Surgery in Evaluating Women With Primary or Recurrent Breast Cancer
RATIONALE: Imaging procedures such as positron emission tomography (PET) may improve the ability to detect the extent of breast cancer.
- Trial name
- NCT00039286
- Testing
- positron emission tomography, radionuclide imaging, fludeoxyglucose F 18
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Memorial Sloan Kettering Cancer Center