Clinical trials: Surgical Procedure
Osteoarthritis
Study of AQUACEL™ Ag Surgical Cover Dressing Following Total Knee Replacement
The aim of the study is to determine whether the AQUACEL™ Ag SURGICAL cover dressing is successful in reducing the incidence of wound infection in high risk patients following total knee replacement.
- Trial name
- NCT02217202
- Testing
- Aquacel Ag dressing
- Sponsor
- Golden Jubilee National Hospital
Low Cardiac Output Syndrome, Cardiac Surgical Procedures
Prophylactic Use of Milrinone After Congenital Heart Surgery in Infants
This randomized, multi-center, double-blinded, placebo-controlled study is designed to evaluate the efficacy and safety of milrinone compared with placebo in participants after corrective surgery for congenital heart disease.
- Conditions
- Low Cardiac Output Syndrome, Cardiac Surgical Procedures, Infant
- Trial name
- NCT03823781
- Testing
- Milrinone, Normal saline
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Shanghai Children's Medical Center
Single Ventricle Defect
Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction
This study seeks to determine cerebral blood flow changes in single ventricle patients during staged surgical reconstruction as compared with normal children.
- Trial name
- CBF (NCT02135081)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital of Philadelphia
Esophageal Atresia
Endoscopic Ultrasound Findings in Esophageal Atresia Following Surgical Repair
Children with esophageal atresia who undergo surgical repair are at risk for anastomotic stricture following surgery. Esophageal stricture can be treated with serial endoscopic dilation but may ultimately need surgical resection…
- Trial name
- NCT04259528
- Testing
- Pediatric endoscopic ultrasound
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Vaginal Cancer
Immediate Vaginal Reconstruction After Oncologic Resection: Surgical Outcomes, Patient Satisfaction and Sexual Function
This study is being done to find out more about the experience women have with vaginal reconstruction. We hope to learn about their quality of life, sexual function, and body image.
- Trial name
- NCT00588081
- Testing
- QOL
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Methicillin-resistant Staphylococcus Aureus Infection
Incidence and Relationship of Positive Preoperative Methicillin Resistant Staphylococcus Aureus (MRSA) Screens and Post-operative Infections
The purpose of this study is to evaluate the prevalence of pre-surgical patients who are MRSA carriers. From an evidence-based practice perspective, findings from this study can be considered in the evaluation of the hospital SOP…
- Trial name
- MRSA (NCT01028105)
- Testing
- Preoperative MRSA screening
- Where
- 2 sites in United States
- Volunteers
- 975 people
- Sponsor
- Inova Health Care Services
Urologic Surgical Procedures, Urinary Bladder, Neurogenic
Pediatric Urology Recovery After Surgery Endeavor (PURSUE)
The purpose of this research study is to evaluate an Enhanced Recovery After Surgery (ERAS) protocol in children and young adults undergoing urologic reconstructive surgery.
- Conditions
- Urologic Surgical Procedures, Urinary Bladder, Neurogenic, Urinary Bladder Diseases
- Trial name
- NCT03245242
- Testing
- Enhanced Recovery after Surgery, Historical usual surgical care
- Where
- 7 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cruciate Ligament Rupture
A Clinical Trial of Precise Positioning and Intelligent Operation of Surgical Robots to Reconstruct Cruciate Ligaments
30 patients with the first rupture of the cruciate ligament were divided into two groups as 1:1. Experimental group will be treated with arthroscopic robot-assisted navigation and positioning for cruciate ligament reconstruction.
- Trial name
- NCT04980183
- Testing
- Arthroscopic surgical robot, Conventional arthroscopic cruciate ligament reconstruction
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Intervention
First-line Nurse Manager Authentic Leadership Training Program
Authentic leadership behavior is considered a mandatory strategy for enhancing the nurse manager capabilities and practice as well as achieving positive nurses' attitudes.
- Trial name
- NCT06366594
- Testing
- Authentic leadership training program
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Matrouh University
Hip Fracture
Single Shot Fascia Iliaca Block vs Femoral Nerve Block for Analgesia for Surgical Fixation of Hip Fractures
Hip fractures are common in our elderly population and is associated with pain before and after surgery. The current pain management for patients who have undergone surgery for hip fractures include a combination of oral…
- Trial name
- NCT02330302
- Testing
- Ropivacaine
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Changi General Hospital
Chronic Pancreatitis
Endoscopic Versus Surgical Treatment of Chronic Pancreatitis
Chronic pancreatitis is a progressive inflammatory disease of the pancreas characterized by destruction of pancreatic parenchyma and subsequent fibrosis.
- Trial name
- NCT01520675
- Testing
- surgery, Endoscopic therapy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- All India Institute of Medical Sciences
Lung Adenocarcinoma, Surgical Procedure, Unspecified
Intraoperative Frozen Section Pathology to Diagnose the IASLC Grades for Lung Adenocarcinoma (ECTOP-1014)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1014). The goal of this clinical trial is to confirm the concordance rate between intra-operative frozen section pathological diagnosis and post-operative…
- Conditions
- Lung Adenocarcinoma, Surgical Procedure, Unspecified, Pathology
- Trial name
- NCT05794698
- Testing
- Surgical resection
- Where
- China
- Volunteers
- 827 people
- Sponsor
- Fudan University
Abdominal Pain
The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's Decision
Surgeons are the individuals who will operate on a patient if it is determined to be necessary after they present with abdominal pain.
- Trial name
- NCT00839787
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Patients With Traumatic Pain, Post-surgical Pain and Tooth Extract Pain
Celecoxib Japan Observational Study for the Patients With Acute Pain
This study is to assess the safety and efficacy of celecoxib on the pain relief from acute pain.
- Trial name
- NCT01876121
- Testing
- Celecoxib
- Where
- 7 sites in Japan
- Volunteers
- 784 people
- Sponsor
- Astellas Pharma Inc
Pericardial Effusion
Surgical Options for Management of Pericardial Effusion
This is a retrospective descriptive study which will be conducted at Sohag university Hospital, Sohag, Egypt at emergency and cardiothoracic department .
- Trial name
- NCT05061914
- Testing
- pericardial effusion drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Heart Diseases, ASD - Atrial Septal Defect
Abbott Structural Heart Device Registry
The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.
- Conditions
- Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale
- Trial name
- SH-Registry (NCT06590467)
- Testing
- Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices
- Where
- 36 sites in United States, Denmark and 8 more
- Volunteers
- 2,500 people
- Sponsor
- Abbott Medical Devices
Esophageal Cancer
Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00006472
- Testing
- carboplatin, fluorouracil, paclitaxel
- Where
- 6 sites in United States
- Volunteers
- 4 people
- Sponsor
- Medstar Health Research Institute
Plasma Volume Substitution (Hypovolemia) Including Massive Hemorrhage
Study to Obtain Volume Effect and Safety Data on 6 % Hydroxyethyl Starch 130/0.4 in Pediatric and Adult Patients Undergoing Major Elective Surgery
The study shall evaluate the volume effect and safety of 6 % hydroxyethyl starch 130/0.4 for restoration and maintenance of hemodynamics during the investigational period in patients undergoing major elective surgery.
- Trial name
- NCT01127477
- Testing
- 1: Hydroxyethyl starch 130/0.4, 6 %
- Where
- 4 sites in Japan
- Volunteers
- 20 people
- Sponsor
- Fresenius Kabi Japan
Congenital Heart Disease in Children, Cardiac Surgical Procedures
Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery
Pediatric cardiac surgery has a relatively high morbi-mortality. Despite great advances in surgical techniques, today the mortality rate is about 3% and morbidity is about 30-40%.
- Conditions
- Congenital Heart Disease in Children, Cardiac Surgical Procedures, Outcome Assessment, Organ Dysfunction Scores
- Trial name
- FPMODS2 (NCT05284500)
- Testing
- Pediatric cardiac surgery with cardiopulmonary bypass
- Where
- Belgium
- Volunteers
- 152 people
- Sponsor
- Brugmann University Hospital
Osteosarcoma
Adjuvant High-Dose Thiotepa and Stem Cell Rescue Associated With Conventional Chemotherapy in Relapsed Osteosarcoma
Approximately 150 new cases of osteosarcoma are reported each year in France, of which 15 to 20% are metastatic. Further to the initial standard care, about 45% of the patients relapse within a median duration of 20 months.
- Trial name
- OSII-TTP (NCT00978471)
- Testing
- Thiotepa
- Where
- 23 sites in France
- Volunteers
- 44 people
- Sponsor
- Centre Leon Berard
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