Clinical trials: Surgical Procedures, Operative
Urinary (Renal or Ureteral) Stones
Comparison Between Two Shock Wave Regimens for Treating Urinary Stones
In order to check if a reduction in the frequency and total number of shocks delivered during extracorporeal shockwave lithotripsy (SWL) results in a great number of stone-free patients,the investigators compared two different…
- Trial name
- NCT01222325
- Testing
- extracorporeal shockwave lithotripsy (SWL)
- Where
- Brazil
- Volunteers
- 302 people
- Sponsor
- University of Sao Paulo General Hospital
Von Willebrand Disease, Blood Coagulation Disorders
Study of Safety and Efficacy of Antihemophilic Factor/Von Willebrand Factor Complex in Surgical Subjects With Von Willebrand Disease (vWD)
The purpose of this study is to test the safety and effectiveness of Humate-P® to prevent bleeding in patients with von Willebrand Disease who are undergoing surgery.
- Conditions
- Von Willebrand Disease, Blood Coagulation Disorders, Blood Platelet Disorders, Hematologic Disease
- Trial name
- NCT00168090
- Testing
- Blood coagulation Factor VIII and vWF, human
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CSL Behring
Abscess
Antibiotic Therapy After Incision and Drainage for Abscess
Background: Skin abscesses are a growing problem in the general pediatric population around the world. While the standard treatment for an abscess/boil is incision and drainage, many physicians also prescribe antibiotics, despite…
- Trial name
- NCT00900510
- Testing
- Incision and drainage, Trimethoprim/Sulfamethoxazole (Bactrim)
- Where
- United States
- Sponsor
- Wake Forest University
Chronic Ankle Instability
A Prediction Model for Chronic Ankle Instability
Chronic ankle instability is a common problem that may follow an ankle sprain. Until a patient has developed chronic ankle instability they are ineligible for surgical treatment although early surgical treatment yields better…
- Trial name
- Predict (NCT02955485)
- Testing
- Patients do not undergo any type of interventions, but standard care if offered and accepted.
- Where
- 4 sites in Netherlands
- Volunteers
- 460 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anxiety
Improving Patient Understanding of the Surgical Hospital Experience: Use of YouTube Video Playlist
This prospective randomized pilot clinical trial studied the effect on preoperative anxiety of watching a series of YouTube videos designed to create a virtual hospital experience for patients undergoing primary total hip and…
- Trial name
- NCT02546180
- Testing
- Viewing YouTube videos, Standard preoperative education
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Septal Defects, Ventricular, Double Outlet Right Ventricle, Noncommitted VSD
A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal Defect
The purpose of this study is to investigate the security and validity of transesophageal echocardiography(TEE)-guided perventricular device closure(TPDC) through minithoracotomy in treatment of infundibular ventricular septal…
- Conditions
- Heart Septal Defects, Ventricular, Double Outlet Right Ventricle, Noncommitted VSD, Double Outlet Right Ventricle, Subaortic VSD, Double Outlet Right Ventricle, Subpulmonary VSD
- Trial name
- NCT02361008
- Testing
- TEE-guided perventricular device closure without CBP, Surgery repair with CBP
- Where
- China
- Volunteers
- 20,121,212 people
- Sponsor
- Bentong Yu
High-Risk Surgical Patients
A Therapy to Reduce Morbidity and Hospital Length of Stay of High-Risk Surgical Patients
Postoperative organ failures commonly occur after major abdominal surgery and substantially increase the utilization of resources and the costs of care, and are favored by tissue hypoxia.
- Trial name
- NCT00254150
- Testing
- Increase oxygen extraction rate
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Università Politecnica delle Marche
Robotic Surgery, Microsurgery
Performance of Robotic Microsurgery Systems
The goal of this preclinical trial is to learn about the benefits and limitations of novel robotic devices for microsurgery, based on different levels of microsurgical experience.
- Conditions
- Robotic Surgery, Microsurgery, Anastomosis
- Trial name
- NCT06146023
- Testing
- Robotic anastomosis (Symani surgical system and RoboticScope), Conventional anastomosis
- Where
- 2 sites in United States, Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Acute Pancreatitis
Late Phase Acute Pancreatitis: a Tailored Step-up Approach
Several interventional and surgical procedures are available to treat moderate-to-critical acute pancreatitis (AP) in its late phase.
- Trial name
- TSA (NCT04870268)
- Testing
- percutaneous drainage, endoscopic approach, surgical internal derivation of WON
- Volunteers
- 47 people
- Sponsor
- University of Pisa
Transcutaneous Monitoring, Microcirculation
Transcutaneous Monitoring of Oxygen and Carbon Dioxide in Surgical Patients
The study will investigate if non-invasive continuous transcutaneous blood gas monitoring can detect tissue perfusion and hypoxemia and the relation to other circulatory parameters such as pulse, blood pressure, cardiac output…
- Conditions
- Transcutaneous Monitoring, Microcirculation, Peripheral Perfusion, Tissue Metabolism
- Trial name
- NCT04040478
- Testing
- Transcutaneous monitoring
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
TAP Block, Cholecystectomy, Laparoscopic
Does the Transversus Abdominis Plane(TAP) Block Effectively Manage Pain After Laparoscopic Cholecystectomy?
The study is about managing pain after laparoscopic gallbladder surgery. Pain after surgery is very common and can affect recovery, delay normal activities, and increase the length of hospital stay.
- Trial name
- NCT07800624
- Testing
- TAP Block
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Surgical Site Infection, Sternal Wound Infection
Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation.
- Trial name
- SWAG (NCT04592328)
- Testing
- Bacterial cultures taken during surgery.
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Physician, Surgeon
Deformable Tissue Modelling and Augmented Reality Based Guidance for Head and Neck Tumor Re-Resection Task
Head and neck cancers have one of the highest recurrence rates among solid malignancies, and recurrence is strongly correlated with overall survival.
- Conditions
- Physician, Surgeon, Resident Doctor, Resident Surgeon
- Trial name
- SPeAR (NCT07686211)
- Testing
- Augmented Reality
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Severe-stage Glaucoma (Mean Deviation ≤ -20 dB)
CVL Risk After Severe Glaucoma Surgery
This retrospective cohort study analyzes risk factors for central visual loss (CVL) after severe-stage glaucoma surgery. The primary hypothesis is that 1) visual prognosis is determined primarily by early postoperative…
- Trial name
- NCT07237555
- Where
- South Korea
- Volunteers
- 523 people
- Sponsor
- Gangnam Severance Hospital
Musculoskeletal Deformity, Musculoskeletal Diseases
Customized Bone Allografts by 3D-printing
Virtual surgical planning (VSP), the simulation of bone corrections in virtual reality ("Computer Aided Surgical Simulation": CASS) and 3D printing of customized implants and devices are achieving an increasingly central role in…
- Conditions
- Musculoskeletal Deformity, Musculoskeletal Diseases, Musculoskeletal Disorder
- Trial name
- 3D-MALF 2 (NCT05700526)
- Testing
- Planning of multiplanar and/or multifocal osteotomies in children by using VSP, PSIs and customized structural bone allograft, Routine preparation of bone graft according to standard protocols, Preparation of bone graft with virtual bone-matching and GSIs
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Healthy Volunteers
Impact of Different Face Masks on Maximal and Submaximal Performance Testing During COVID-19
In COVID 19, masks wearability has become a new normal and this "new normal" presented evidence-based performance limitations. The study findings are aimed to objectify parametric changes (if any) and therefore, will assist in…
- Trial name
- NCT05150613
- Testing
- No Mask, Surgical Mask, N95 Mask
- Where
- 2 sites in Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Surgical Condition, Obstetrical Condition
Validity of Information Employed to Generate Standardized Mortality Ratios Using Hospital Administrative Databases (RNMH)
In a retrospective cross-sectional study, investigators aimed to valid the variables employed to generate standardized mortality ratio from hospital administrative databases.
- Conditions
- Surgical Condition, Obstetrical Condition, Hospitalization in Acute Care
- Trial name
- RNMH (NCT02816320)
- Testing
- Hospitalization
- Volunteers
- 715 people
- Sponsor
- Hospices Civils de Lyon
Pulmonary Regurgitation, Tetralogy of Fallot
Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p
Venus-P Valve (Venus Medtech, Shanghai, China) is the first self-expandable interventional Pulmonary Valve, which is composed of a Nitinol multilevel support frame with a tri-leaflet porcine pericardial tissue valve, and a 14-22…
- Trial name
- Venus-P (NCT02590679)
- Testing
- Venues-P Valve
- Where
- 3 sites in China
- Volunteers
- 44 people
- Sponsor
- Shanghai Zhongshan Hospital
Attenuated Familial Adenomatous Polyposis, Deleterious Familial Adenomatous Polyposis
Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program
The primary objective of this chart review study is to evaluate the outcomes of subjects with Attenuated Familial Adenomatous Polyposis (AFAP) and Deleterious Familial Adenomatous Polyposis (FAP) who have not undergone surgical…
- Trial name
- NCT02747862
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Facial Paralysis
A Study of NTX-001 in the Treatment and Prevention of Facial Paralysis Requiring Surgical Repair.
This study involves the use of an Investigational Product called NTX-001. It is a product used in the repair of nerve injuries. It is used in the operating room.
- Trial name
- NCT05293522
- Testing
- NTX-001
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- Neuraptive Therapeutics Inc.