Clinical trials: Surgical Procedures, Operative
Acromegaly
Surgical Versus Medical Treatment of Acromegaly
Evaluate biochemical differences in acromegalic patients treated with surgery versus somatostatin analogues (SMS) (after surgery or alone). Hypothesis: Treatment modality exhibit different biochemical responses in acromegaly.
- Trial name
- NCT01000090
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Aarhus
Pediatric Liver Transplanted Recipients, Healthy Donors
Living Donor Liver Transplantation in Children
Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.
- Trial name
- NCT02124382
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Dental Trauma
Evaluation of Functional Versus IADT Splinting Times on Tooth Mobility After Surgical Extrusion
The objective of this study is to compare functional splinting time effect versus the suggested splinting time of (IADT) effect on tooth mobility and possible healing outcomes for surgically extruded permanent anterior teeth with…
- Trial name
- NCT03700866
- Testing
- Functional splinting time
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cortical Dysplasia
Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy
The investigators are undertaking the first European Randomised Controlled Trial (RCT) for epilepsy surgery in children with FCD type II, to prospectively evaluate the role of the KD prior to surgery in improving seizure outcome.
- Trial name
- EDIBLE (NCT02261753)
- Testing
- Classical ketogenic diet
- Where
- 15 sites in United States, Austria and 6 more
- Volunteers
- 3 people
- Sponsor
- University College, London
Cruciate Ligament Rupture
A Clinical Trial of Precise Positioning and Intelligent Operation of Surgical Robots to Reconstruct Cruciate Ligaments
30 patients with the first rupture of the cruciate ligament were divided into two groups as 1:1. Experimental group will be treated with arthroscopic robot-assisted navigation and positioning for cruciate ligament reconstruction.
- Trial name
- NCT04980183
- Testing
- Arthroscopic surgical robot, Conventional arthroscopic cruciate ligament reconstruction
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Gastric Neoplasm
Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)
To compare left thoraco-abdominal approach with abdominal and transhiatal approach to cardia or subcardia cancer
- Trial name
- NCT00149266
- Testing
- Surgery: abdominal and transhiatal approach, Surgery: left thoraco-abdominal approach
- Where
- Japan
- Volunteers
- 167 people
- Sponsor
- Japan Clinical Oncology Group
Hypospadias, Distal Penile Hypospadias (Disorder)
Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomized Trial
This randomized controlled trial evaluates the effect of adding Byar's flap in combination with double dartos flap coverage during tubularized incised plate (TIP) urethroplasty in children with distal hypospadias.
- Trial name
- DD-TIP-BF (NCT07525570)
- Testing
- Double Dartos Flap Coverage, Byar's Flap + Double Dartos Flap
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Javaid Afridi
Ingrown Toenail (Onychocryptosis)
Comparison of Two Surgical Methods (Winograd vs. Sleeve Method) in the Treatment of Ingrown Toenail.
This randomized clinical trial aims to compare the recurrence rates of two surgical techniques-Winograd procedure and sleeve (gutter) method-in the treatment of ingrown toenails (onychocryptosis).
- Trial name
- NCT07547241
- Testing
- Winograd Technique, Sleeve (Gutter) Method
- Where
- Pakistan
- Volunteers
- 312 people
- Sponsor
- Pakistan Institute of Medical Sciences
Periodontitis
Effects of Prebiotic Oral Healthcare Products as an Adjunct to Non-surgical Periodontal Therapy
The aim of this study is to determine the impact of a prebiotic toothpaste and mouthrinse in periodontitis patients as an adjunct to scaling and rootplaning.
- Trial name
- NCT02520375
- Testing
- Prebiotic, Control
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Choledochal Cyst
Clinical Features and Prognosis of Asymptomatic Biliary Dilatation
This study is a multicenter, ambidirectional cohort study aiming to consecutively recruit asymptomatic biliary dilation patients incidentally discovered by imaging from 25 medical centers across China.
- Trial name
- NCT07028164
- Where
- China
- Volunteers
- 1,008 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Hypospadias, Urinary Diversion
Evaluation of the Method and Duration of Urinary Diversion in the Management of Distal Penile Hypospadias Following Surgical Repair.
This study aims to conduct a head-to-head comparison to determine the optimal method and duration of urinary diversion following distal penile hypospadias repair.
- Trial name
- NCT07421271
- Testing
- Application of urethral catheter alone for 1 week., Application of urethral catheter alone for 2 weeks., Application of urethral stent and suprapubic catheter for 1 week
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Ain Shams University
Abdominal Surgery, Surgical Site Infection
FALCON Trial Testing Measures to Reduce Surgical Site Infection
FALCON is a Pragmatic multi-centre trial testing measures to reduce superficial or deep skin infection following abdominal surgery in low and middle income countries. The trial will recruit patients undergoing abdominal surgery.
- Trial name
- FALCON (NCT03700749)
- Testing
- 2% chlorhexidine + non-coated suture, 2% chlorhexidine + coated suture, 10%povidone-iodine + non-coated suture
- Where
- Nigeria
- Volunteers
- 5,480 people
- Sponsor
- University of Birmingham
Skin Disease, Bacterial, Abscess
Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage
The objective of this study is to determine if there is a difference in treatment failures and recurrent skin infections when patients are given 3 or 10 days of antibiotics for uncomplicated skin abscesses after they have been…
- Trial name
- NCT02024867
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Lucy Holmes, MD
Developmental Dysplasia of the Hip
Arthroscopically Assisted Versus Open Surgical Reduction of the Hip in Patients With Irreducible DDH Before the Walking Age
To determine the role of arthroscopy in treatment of the DDH.
- Trial name
- NCT06408987
- Testing
- arthroscopically assisted, open surgical reduction
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Assiut University
Knee Osteoarthritis
Validation of a New Technique for the Evaluation of the Patello-femoral Joint Kinematics
The objective of this study is to validate a new technique for intraoperative quantification of the patello-femoral joint kinematics in patients undergoing total knee replacement, and for postoperative quantification of implanted…
- Trial name
- CINE-FEMORO (NCT03448198)
- Testing
- Total knee replacement
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Skin Barrier to Water Loss, Skin Health
Apple Peptide Complex for Post-Surgical and Aesthetic Skin Recovery
This clinical study evaluates a topical botanical formulation for supporting skin recovery following invasive and non-invasive aesthetic procedures.
- Conditions
- Skin Barrier to Water Loss, Skin Health, Skin Discoloration, Skin Irritation
- Trial name
- APC-SKIN (NCT07807085)
- Testing
- Apple Peptide Complex Post-Aesthetic Care Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Grow Out Oils Clinical Aromatherapy Company
Basal Cell Carcinoma, BCC
The Efficacy and Safety of Using Intralesional 5-fluorouracil for Basal Cell Carcinoma
The investigators want to assess the safety and efficacy of using intralesional 5-FU for the management of different types of BCC (including all the types EXCEPT the infiltrative one), by estimating different outcomes after the…
- Trial name
- NCT06150144
- Testing
- 5-Fluorouracil, SURGERY
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- University of Aleppo
Bacterial Contamination
Bacterial Contamination on Obstetric Resident Surgical Scrubs
This study will determine if there is a difference in bacterial contamination (CFU/cm2) between obstetric resident surgical scrubs donned at home and those donned at the hospital.
- Trial name
- NCT02348866
- Testing
- method of laundering and donning scrubs
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Surgical Simulation Education
Assessment of the Transferability of Skills From Robotic to Laparoscopic Simulation Platforms
This is a randomized controlled trial that will randomize 40 surgical skill naive medical students to practice on a robotic simulator or laparoscopic simulator after first completing a baseline evaluation on both surgical…
- Trial name
- NCT02370407
- Testing
- a laparoscopic simulator (Fundamentals of Laparoscopic Surgery (FLS), VT Medical Inc, Waltham, MA), Mimic da Vinci robotic simulator
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Episiotomy
Efficacy of Triclosan-coated Sutures in the Episiotomy
Surgical repair of perineal lesions after delivery can be associated with infection of the surgery site. The aim of this study was to compare the surgical site infection with triclosan-coated suture (Vicryl Plus) versus coated…
- Trial name
- EPISIOVIC (NCT02847936)
- Testing
- vicryl plus suture, vicryl suture
- Where
- Tunisia
- Volunteers
- 400 people
- Sponsor
- University Tunis El Manar
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