Clinical trials: Surgical Risk Prediction
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Cardiovascular Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after cardiac and vascular surgery.
- Trial name
- NCT04926012
- Where
- 5 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Huazhong University of Science and Technology
Pediatric Surgical Patients
Evaluation of Preoperative Risk Factors in Children
This study aimed to evaluate preoperative risk factors in pediatric patients and to determine their effectiveness in predicting intensive care unit admission within 72 hours.
- Trial name
- NCT05852899
- Where
- Turkey (Türkiye)
- Volunteers
- 326 people
- Sponsor
- Istanbul University - Cerrahpasa
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Acute Kidney Injury
Preoperative Prediction of Acute Kidney Injury After Cardiac Surgery
Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk are lacking. Renal functional reserve (RFR), the capacity of the intact nephron mass to increase glomerular filtration rate…
- Trial name
- RFR (NCT03092947)
- Testing
- No intervention
- Volunteers
- 110 people
- Sponsor
- University of Giessen
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Emergency Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after emergency surgery.
- Trial name
- NCT04926038
- Where
- 5 sites in China
- Volunteers
- 200,000 people
- Sponsor
- Huazhong University of Science and Technology
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Pituitary Adenoma
Pre-operative Surgical Difficulty Stratification Using Predicted Tumor Perfusion and Consistency
Pituitary adenomas (PAs) are among the most prevalent lesions of the sella turcica, accounting for 10%-25% of all intracranial neoplasms. Pituitary macroadenomas (PMAs) are defined with a maximum diameter of over 1 cm.
- Trial name
- NCT06664190
- Testing
- Advanced sequences, such as arterial spin labeling (ASL) and diffusion-weighted imaging (DWI)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Huashan Hospital
Pre-operative, High-risk Patient
Practice Variation in Preoperative Multidisciplinary Team Discussions
Preoperative multidisciplinary team (MDT)discussions are recommended by national and international guidelines. However, no guidance is given on how to organise and execute an MDT discussion.
- Conditions
- Pre-operative, High-risk Patient, Frailty
- Trial name
- NCT05305053
- Testing
- preoperative MDT discussion
- Where
- 9 sites in Netherlands
- Volunteers
- 225 people
- Sponsor
- Rijnstate Hospital
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Noonan Syndrome
Link Between Abnormal Bleeding and Coagulation Disorders in Noonan Syndromes
Noonan syndrome is a relatively rare genetic disorder, affecting around 1 in every 1,000 to 2,500 children born. Patients often have a tendency to bleed more easily, particularly from the skin or mucocutaneous tissue (such as…
- Trial name
- PlatNoon (NCT07259135)
- Testing
- Reuse of routine clinical and biological data
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Lumbar Disc Herniation, Lumbar Degenerative Disease
Multivariate Analysis and Machine Learning Model Risk Prediction of Recurrent Pain After PLIF Surgery for Degenerative Lumbar Spine Disease At Long-term Follow-up
The study was a clinical retrospective study designed to investigate risk factors for long-term recurrent pain after PLIF in patients with lumbar degenerative disease and to improve patient outcomes
- Conditions
- Lumbar Disc Herniation, Lumbar Degenerative Disease, Sarcopenia
- Trial name
- NCT06622356
- Testing
- MRI with Eovist
- Where
- China
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Primary Angle-Closure Glaucoma
Predicting the Risk of Partial Ciliary Block After Cataract and Goniosynechialysis Surgery in Primary Angle-Closure Disease
Primary angle-closure disease (PACD) is a major cause of vision loss, often treated with a combined surgery that removes the eye's natural lens (cataract surgery) and physically opens the eye's drainage system…
- Trial name
- PCB-Risk (NCT07549438)
- Volunteers
- 1,150 people
- Sponsor
- Peking University People's Hospital
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Prolonged Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after prolonged surgery.
- Trial name
- NCT04926025
- Where
- 5 sites in China
- Volunteers
- 500,000 people
- Sponsor
- Huazhong University of Science and Technology
Surgical Site Infection (SSI), Central Nervous System Tumor
A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery
1. Study Background For patients undergoing brain or spinal tumor surgery, postoperative surgical wound infection (known as "surgical site infection," SSI) is a recognized risk.
- Trial name
- NCT07378683
- Testing
- ML-Based Enhanced Intervention Package for SSI Prevention, Standard Postoperative Care
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ming Yang
Epilepsy, Surgery--Complications
Complications After Epilepsy Surgery
Epilepsy surgery is effective for refractory epilepsy, particularly focal epilepsy, but is still underutilized worldwide. In the United States, the annual percentage of surgical procedures for refractory epilepsy was low (range…
- Trial name
- NCT04727892
- Testing
- epilepsy surgery
- Volunteers
- 2,026 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Hypothermia, Accidental, Hypothermia; Anesthesia
Constructing a Risk Prediction Model for Intraoperative Hypothermia in Children Under General Anesthesia
Intraoperative hypothermia refers to a core body temperature below 36.0°C during surgery, which is common in surgical patients. Due to the fact that children's body temperature regulation function is not yet fully developed, they…
- Trial name
- NCT06892795
- Where
- China
- Volunteers
- 562 people
- Sponsor
- Harbin Medical University
Brachial Plexus Injury
A Multicenter External Validation of a Novel Prediction Model for Elbow Flexion Recovery After Nerve Transfer Surgery in Brachial Plexus Injuries
The goal of this observational study is to validate a risk prediction model developed for unsuccessful elbow flexion recovery after nerve transfer surgery in patients with brachial plexus injury.
- Trial name
- NCT06237270
- Testing
- Nerve transfer surgery for elbow flexion
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Siriraj Hospital
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Gastric Cancer (GC)
Development and Validation of the Surgical Assessment and Healthcare (SAH) Index for Gastric Cancer Treatment Evaluation
This study develops the Surgical Assessment and Healthcare (SAH) Index, a new tool to fairly evaluate gastric cancer surgery outcomes.
- Trial name
- SAH (NCT07180966)
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Ruijin Hospital
Aortic Regurgitation
Cardiac T1 Mapping Enables Risk Prediction of LV Dysfunction After Surgery for Aortic Regurgitation
To assess whether cardiac T1 mapping for detection of myocardial fibrosis enables preoperative identification of patients at risk for early left ventricular dysfunction after surgery of aortic regurgitation.
- Trial name
- NCT05332184
- Testing
- aortic valve surgery
- Volunteers
- 40 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf