Clinical trials: Thoracotomy
Pulmonary Malformation
Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection
The National Rare Diseases plans, the ongoing MALFPULM PHRC and thoracoscopic advents in children, are remarkable improvements in understanding and managing lung malformations.
- Trial name
- 3DLP (NCT03913416)
- Testing
- 3D printed model, Control group
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative
Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion
The main objective of this proposed investigation is to evaluate blood ropivacaine concentrations in infants and toddlers following the initiation of, and over the course of, continuous paravertebral nerve blockade using…
- Trial name
- NCT02860091
- Testing
- Ropivacaine infusion
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston Children's Hospital
Pain, Acute, Breathing, Mouth
Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume
Pain is a subjective, sensory and emotionally unpleasant experience resulting from real or hidden injuries in tissues. The pain experience is a subjective and unique experience in physiological and psychological terms and is the…
- Conditions
- Pain, Acute, Breathing, Mouth, Relaxation; Diaphragm, Cough
- Trial name
- NCT07411417
- Testing
- Acupressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Özgül Aydemir
Non Small Cell Lung Cancer
Multicentric Analysis of Predictors of N1 Upstaging After Resection of cStage-I NSCLC
Five papers showed a lower N1 nodal upstaging with video-assisted thoracic surgery (VATS) compared to open surgery in patients with cStage-I NSCLC .
- Trial name
- NUTS (NCT02730897)
- Testing
- Central/Peripheral
- Volunteers
- 956 people
- Sponsor
- University Hospital, Gasthuisberg
Lung Cancer, Quality of Life
Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain.
- Conditions
- Lung Cancer, Quality of Life, Video-assisted Thoracic Surgery (VATS), Thoracotomy
- Trial name
- NCT00598000
- Testing
- questionnaires
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pain, Postoperative, Surgery, Thoracic
Influence of Preoperative Support on Anxiety, Pain and Satisfaction With Postoperative Analgesia
The aim of this study was to analyze a relationship between information support provided by an interdisciplinary team and the levels of anxiety, pain and satisfaction with postoperative analgesia in children and adolescents…
- Trial name
- NCT03488459
- Testing
- Routine preoperative information from a nurse, Additional information support from a psychologist
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Ultrasound Guided Block, Pediatric Surgery
Mid-transverse Process to Pleura Block in Pediatric Thoracotomy
The aim of this study is to assess the effectiveness of analgesia of US guided MTP block in pediatrics undergoing thoracotomy.
- Conditions
- Ultrasound Guided Block, Pediatric Surgery, Analgesia
- Trial name
- NCT05999734
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Post Operative Pain
Ketamine Improves Post-Thoracotomy Analgesia
Thoracotomy for lung tumor or for minimally invasive direct coronary artery bypass (MIDCAB) surgery, may be associated with debilitating pain. Ketamine was shown to enhance opioid antinociception and prevent opioid resistance.
- Trial name
- NCT00625911
- Testing
- morphine, morphine ketamine
- Where
- Israel
- Volunteers
- 44 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cardiac Surgery Subjects
Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumption in Patients Who Will be Operate by Thoracotomy and Sternotomy in Cardiac Surgery
The study aims to test the relationship between the preoperative pain threshold and the intraoperative need for opioids. The objective of the study is to try to predict a patient's analgesic needs based on their objectively…
- Trial name
- NCT07513974
- Testing
- Measure of the minimal pain threshold with an algometer
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Hemopneumothorax, Pneumothorax
Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax
The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.
- Trial name
- NCT01127880
- Testing
- Ancef or Clindamycin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Mitral Valve Reconstruction
Clinical Comparative Analysis of Bretschneider and St. Thomas Cardioplegia Solution in Case of Mitral Valve Repair Via Anterolateral Right Thoracotomy
Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy is done in cardioplegia with a cardioplegic solution, either HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St.
- Trial name
- NCT03818113
- Testing
- cardioplegia with HTK-Bretschneider cardioplegic solution, cardioplegia with St. Thomas cardioplegic solution
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Basel, Switzerland
Emergencies, Trauma
Comparison of Two Resuscitative Thoracotomy Techniques
Resuscitative thoracotomy (RT) is a life saving procedure for patients who have suffered cardiac arrest or are at significant risk of cardiac arrest following significant trauma.
- Conditions
- Emergencies, Trauma, Procedural Training, Thoracotomy
- Trial name
- NCT04242160
- Testing
- Modified Clamshell Thoracotomy, Left Anterolateral Thoracotomy
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Anesthesia, Local
Serratus Anterior Plane Block in Pediatric Patients
The aim of this work is to study the efficacy of ultrasound guided serratus anterior plane block in pediatric patients undergoing thoracic surgeries. It is a randomized controlled trial.
- Trial name
- NCT04444635
- Testing
- Serratus Anterior Plan Block+ Fentanyl infusion, Fentanyl
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Lung Cancer, Thoracic Cancer
Exploring Robotic-assisted Thoracic Surgery for Lung Cancer
Background Surgery for lung cancer can be performed using open (thoracotomy) or minimally invasive techniques (Video Assisted Thoracic Surgery (VATS)).
- Conditions
- Lung Cancer, Thoracic Cancer, Surgery
- Trial name
- ROSE (NCT03658083)
- Testing
- Thoracotomy, Robotic-assisted thoracic surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Teesside University
Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary…
- Conditions
- Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma, Osteosarcoma
- Trial name
- NCT05235165
- Testing
- Biospecimen Collection, Computed Tomography, Questionnaire Administration
- Where
- 233 sites in United States, Australia and 4 more
- Volunteers
- 62 people
- Sponsor
- Children's Oncology Group
Post Operative Pain
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
A double-blind randomized control study to compare the efficacy of dexmedetomidine versus ketamine as an adjuvant in combination with bupivacaine ultrasound-guided ESP block in patients scheduled for cardiothoracic surgeries with…
- Trial name
- NCT05552391
- Testing
- Bupivacaine, Ketamine Hydrochloride, Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kasr El Aini Hospital
Pain, Postoperative
Continuous Erector Spinae Block Versus Continuous Paravertebral Block
Overall Aim: To evaluate the efficacy of continuous erector spinae block (ESB) versus continuous paravertebral block (PVB) for postoperative analgesia in children and adolescents undergoing surgical procedures via unilateral…
- Trial name
- NCT03768440
- Testing
- continuous erector spinae block (ESB), continuous paravertebral block (PVB), Ropivacaine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pneumothorax
Video-assisted Thoracic Surgery (VATS) Versus Axillary Mini-thoracotomy for the Treatment of Recurrent Spontaneous Pneumothorax
The investigators conducted a prospective randomized study to compare axillary minithoracotomy versus a modified two-port thoracoscopic technique for surgical pleurodesis in patients with recurrent spontaneous pneumothorax…
- Trial name
- NCT01192217
- Testing
- Modified thoracoscopic technique, Axillary mini-thoracotomy
- Where
- Greece
- Volunteers
- 66 people
- Sponsor
- AHEPA University Hospital
Ultrasound, Serratus Anterior Plane Block
Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy
This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy
- Conditions
- Ultrasound, Serratus Anterior Plane Block, Thoracic Erector Spinae Plane Block, Post Operative Analgesia
- Trial name
- NCT06862518
- Testing
- Control group, Serratus Anterior Plane Block (SAPB) group, Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Pain, Postoperative
Chronic Pain Following Thoracic Surgery
Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem.
- Trial name
- PTPS-18 (NCT01144845)
- Testing
- Thoracic surgery
- Where
- Denmark
- Volunteers
- 702 people
- Sponsor
- University of Aarhus