Clinical trials: Tooth
Pulp Necroses
Revascularization of Immature Anterior Necrotic Teeth
The object of this study is to compare the effect of Calcium Hydroxide and Di-antibiotic paste as intracanal disinfectants in the 1st visit of revascularization of necrotic immature permanent anterior teeth.
- Trial name
- NCT03504332
- Testing
- intracanal disinfection in revascularization
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child
Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy. Hypothesis: the administration of probiotics during infancy has no effect on future dental health.
- Trial name
- NCT01424852
- Testing
- Probiotics in infant milk formula
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Turku
Dental Caries, Early Caries Lesions
A Randomized Split-Mouth Clinical Trial Comparing Resin Infiltration and Microabrasion for Early Caries Lesions
This study aims to evaluate and compare the clinical characteristics and treatment outcomes of early caries lesions using resin infiltration (Icon) and microabrasion (Opalustre).
- Conditions
- Dental Caries, Early Caries Lesions, White Spot Lesions[Initial Caries]on Smooth Surface of Tooth
- Trial name
- ICON-CTU (NCT07544849)
- Testing
- Resin Infiltration, Microabrasion
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Dental Trauma, Enamel Hypoplasia
Evaluation of Sequelae in Permanent Successors Following Traumatic Injuries to Primary Teeth
Retrospective data analysis of children with primary dental trauma and follow-up visual examination to find out the sequelae.
- Conditions
- Dental Trauma, Enamel Hypoplasia, Sequelae, Sequelae Successors
- Trial name
- NCT07134348
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Zeynep Aslı GÜÇLÜ
Class II Malocclusion, Division 1
Evaluation of 3D Printed Modified Twin Block for Correction of Skeletal Class II Malocclusion in Growing Females
The study is to evaluate the effect of 3D printed modified Twin Block Appliance on skeletal Class II profile correction. The null hypothesis of this research is that use of 3D Printed Twin Block is not able to induce skeletal…
- Trial name
- NCT04028661
- Testing
- 3D printed Modified Twin Block Appliance
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mood Disorders
Neurofilament Light Chain Correlation With Severity of Symptoms and Cognitive Decline in Mood Disorders
Explore correlation of neurofilament light chain serum level and severity of symptoms and cognitive impairment in mood disorders Explore How novel brain markers as neurofilament light chain can be useful in detection and…
- Trial name
- NCT06877442
- Testing
- serum level of neurofilament light chain
- Volunteers
- 90 people
- Sponsor
- Assiut University
Demineralisation, White Spot Lesions
A Trial of Tooth Mousse to Remineralise Post-orthodontic Treatment White Spot Lesions
Fixed dental braces are associated with the risk of developing White Spot Lesions (WSLs), which appear as white chalky marks on the teeth.
- Conditions
- Demineralisation, White Spot Lesions, Orthodontic Treatment
- Trial name
- NCT01344473
- Testing
- Tooth Mousse creme (Casein Phosphopeptide)(RECALDENT)
- Where
- 2 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Dundee
Dental Deformity, Malocclusion
Orthognathic Surgery With Clear Aligners vs Conventional Brackets
This retrospective single-center observational study compared perioperative and early postoperative outcomes in patients undergoing orthognathic surgery after orthodontic preparation with either conventional fixed brackets or…
- Conditions
- Dental Deformity, Malocclusion, Orthognathic Surgery
- Trial name
- NCT07511296
- Testing
- Conventional fixed orthodontic appliances, Clear aligner therapy
- Where
- France
- Volunteers
- 420 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries
Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients
90 saliva samples will be isolated from patient who possess different ages and caries activity, attending outpatient clinic of October University of Modern Sciences and Arts.
- Trial name
- NCT03802669
- Testing
- oral mutans streptococcus
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Root Canal Therapy
Treatment Durations for Endodontic Procedures
The aim of this observational study is to compare the treatment durations of different stages of routine root canal therapy performed on maxillary molar teeth using direct vision, magnification loupes, and a dental operating…
- Trial name
- NCT07304869
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Uşak University
Extracting Own Teeth, Bone Substitutes
Study of Alveolar Bone Preservation Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial
Bone graft added to the dental socket immediately after tooth extraction prevents atrophy and deformity of the bone at the site of element loss, enabling rehabilitation with implants.
- Trial name
- NCT06150456
- Testing
- extraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Class III Malocclusion, Hyoid Bone
The Effect of Orthopedic Face Mask Use on Head Posture and Pharyngeal Airway
The aim of this study was to evaluate the changes in head posture, position of the hyoid bone, pharyngeal airway and cervical posture after the use of Petit type face mask in patients with skeletal class III malocclusion (ANB…
- Trial name
- NCT05114642
- Testing
- Skeletal Class III Malocclusion Treatment with Face Mask Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Taner OZTURK, DDS, MS
Pulp Necrosis, Irreversible Pulpitis
CLINICAL AND RADIOGRAPHIC SUCCESS OF MODIFIED LSTR TECHNIQUES IN PRIMARY SECOND MOLARS
This study aimed to evaluate and compare the clinical and radiographic success of different antibiotic and vehicle modifications of the Lesion Sterilization and Tissue Repair (LSTR) technique in infected mandibular primary second…
- Trial name
- NCT07836686
- Testing
- 3Mix-MP Antibiotic Paste, 3Mix-NS Antibiotic Paste, 2Mix-MP Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Uşak University
Maxillary Transverse Deficiency
Evaluation of the Effect of Surgically Assisted Rapid Maxillary Expansion on Tooth Color
This prospective study aimed to evaluate effects of surgically assisted rapid maxillary expansion (SARME) on the color, maxillary anterior teeth by comparing them with untreated control group.
- Trial name
- NCT07150572
- Testing
- surgery assisted rapid maxillary expansion
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Crowding, Tooth, Class I
Comparison Between the Effectiveness of Different Commercial Bracket Brands
There's a scarcity in literature concerning the comparison of the effectiveness of brackets in its torque and tip ability, the time takes for leveling and alignment comparing between different orthodontic bracket brands, and its…
- Trial name
- NCT05333094
- Testing
- Brackets
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pain, Postoperative Pain
Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins
The aim of this study is to compare the effect of Neem (azadirachta indica) and 2.5% sodium hypochlorite as root canal irrigants on the intensity of post-operative pain and the amount of endotoxins in necrotic teeth.
- Conditions
- Pain, Postoperative Pain, Postoperative Complications, Necrosis
- Trial name
- NCT03312153
- Testing
- Neem, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Hypomineralization, Incisor
Comparison of the Long-Term Success of Different CAD-CAM Blocks Used as Indirect Restorations in Molar Incisor Hypomineralized Teeth: A Split Mouth Study
This study is about the long-term survival success of different, externally prepared fillings (Indirect restoration, CAD-CAM blocks) used in teeth with reduced mineral structure, namely Molar Incisor Hypomineralization (MIH)…
- Trial name
- NCT07144605
- Testing
- CAD-CAM, indirect restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
White Spot Lesions, Demineralization
Comparative Effectiveness of Remineralization Agents on Attachment-Associated Demineralization in Clear Aligner Patients
Background/ Objectives: Clear aligner attachments increase the risk of white spot lesions (WSL), with a 35.5% incidence in adolescents. The number of anterior attachments is an independent risk factor (OR=2.192).
- Conditions
- White Spot Lesions, Demineralization, Dental Caries, Orthodontic Treatment
- Trial name
- NCT07229105
- Testing
- GC Tooth Mousse, Nano-Hydroxyapatite Gel, Sodium Fluoride varnish
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Pulp Necrosis, Apexification
Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth
This study was conducted to evaluate the effect of the use of apical matrix, with Mineral Trioxide Aggregate (MTA) or calcium hydroxide Ca(OH)2 Apexification on apical healing and calcific barrier formation of immature teeth with…
- Trial name
- NCT03849222
- Testing
- Apexification, MTA, Ca(OH)2
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
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