Clinical trials: Treatment Outcomes
Complex Care, Medical Complexity
Complexity in Health, Education, and Social Support for Children and Young People With Life-limiting Conditions.
Children and young people (CYP) with life-limiting conditions represent a growing population with complex care needs that span health, education, and social care systems.
- Conditions
- Complex Care, Medical Complexity, Pediatrics, Life-limiting Illness
- Trial name
- CHESS (NCT07102433)
- Testing
- Children and young people with life-limiting conditions, their parents/carers, and professionals across healthcare, education, and social care sectors.
- Where
- 5 sites in United Kingdom
- Volunteers
- 170 people
- Sponsor
- King's College London
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Anorexia Nervosa
Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa is a serious life-threatening illness with a typical age of onset in adolescence; if not effectively treated, it has the potential to significantly impact adolescent development and quality of life.
- Trial name
- NCT03928028
- Testing
- Cognitive Remediation Therapy, Family Based Treatment
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Children's Hospital of Philadelphia
Pulmonary Hypertension, Pregnancy, High Risk
Pregnant Women With Pulmonary Hypertension in China
Little is known about the status of maternal, obstetric and neonatal complications and the potential predictors of developing heart failure (HF) in the mothers with pulmonary hypertension in China.
- Trial name
- NCT05198206
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Premature Birth of Newborn
Supporting and Enhancing NICU Sensory Experiences (SENSE)
Seventy preterm infants born less than or equal to 32 weeks gestation were put into either the sensory-based intervention (experiment) group or traditional care (control) group. Consecutive admissions at St.
- Trial name
- SENSE (NCT03316547)
- Testing
- SENSE Program
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acetabular Fracture
Pediatric Acetabular Fracture Registry
The investigators primary objective is to determine the fracture patterns, displacement-based treatment decisions, immediate and long-term complications, clinical, radiographic and patient reported outcomes of acetabular…
- Trial name
- NCT07609758
- Testing
- Retrospective acetabular fracture, Prospective acetabular fracture
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Utah
Focal Segmental Glomerulosclerosis
LDL-Apheresis for FSGS CardioRenal Outcomes
Focal segmental glomerulosclerosis (FSGS) is the most common cause of end-stage renal disease (ESRD) in adolescents. The refractory nature of FSGS and a more than 30% recurrence rate after kidney transplantation renders treatment…
- Trial name
- NCT04088799
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
School Based Intervention
Impact of School Based Intervention on Motivation Towards Physical Activity and Psychosocial Outcomes Among Adolescents
This study examines the effect of self designed school-based interventions on physical activity and psychological outcomes (i.e., internalizing and externalizing behavioral symptoms, self-concept, and academic achievement among a…
- Trial name
- NCT04487132
- Testing
- Active physical education lessons and physical education plan, Recess or lunch time activities
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Fontan Procedure
Clinical Outcomes in Fenestrated Extra-Cardiac Fontan in Low Preoperative Risk Profiles
Evaluation of fenestration benefit in Extra-cardiac total cavo-pulmonary connection (Fontan procedure) in single ventricle anomaly, comparing clinical outcomes of patients with low preoperative risk profiles in prospective study
- Trial name
- NCT03503032
- Testing
- Extracardiac Fontan, Fontan fenestration
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Recession, Gingival
Long-term Outcomes of Tunnel Technique
Few studies evaluate the outcomes beyond 1 year follow up for gingival recessions treatments using the tunnel technique in combination with connective tissue graft.
- Trial name
- NCT04016493
- Testing
- Connective tissue graft
- Volunteers
- 40 people
- Sponsor
- University of Liege
Coronary Artery Perforation
Covered Stents in Treatment of Coronary Artery Perforation
Covered stents have been mainly used for treatment of potentially life-threatening coronary artery perforation and coronary artery aneurysm.
- Trial name
- CRACK (NCT04630314)
- Testing
- Percutaneus Coronary Intervention
- Where
- 6 sites in Poland
- Volunteers
- 119 people
- Sponsor
- Medical University of Silesia
Diabete Type 1, Ketoacidosis, Diabetic
Hemoglobin Levels and Resolution Time of Diabetic Ketoacidosis in Pediatric Patients
This retrospective observational cohort study aims to evaluate the association between hemoglobin levels and the time to resolution of diabetic ketoacidosis (DKA) in pediatric patients.
- Conditions
- Diabete Type 1, Ketoacidosis, Diabetic, Pediatrics, Child
- Trial name
- NCT07377604
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Aydin Adnan Menderes University
Lung Diseases, Asthma
Better Asthma Outcomes: Lowering Tobacco Smoke Exposure
To improve disease outcomes through reduction in secondhand tobacco smoke exposure of children with asthma
- Trial name
- NCT00217958
- Testing
- SHS reduction intervention based on social cognitive learning theory
- Sponsor
- Palo Alto Medical Foundation
Endometriosis, Uterine Fibrioids
A Study to Evaluate Pregnancy Outcomes in Females Treated With Oral Elagolix Tablets and Capsules
Orilissa is a drug approved for the management of moderate to severe pain associated with endometriosis. Oriahnn is approved for heavy menstrual bleeding due to uterine fibroids.
- Trial name
- NCT04464187
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- AbbVie
Toxemia
Predicting Complications in Women With Toxaemia
At present, the management of pre-eclampsia is guided by expert opinions that are not well-based on firm evidence. What is required is a clinical tool that can accurately determine a women's risk for adverse outcomes, and thereby…
- Trial name
- NCT00175526
- Testing
- preeclampsia
- Where
- 6 sites in Canada, New Zealand and 1 more
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Severe Eosinophilic Asthma
Real World Evidence of Benralizumab in Eosinophilic Severe AsThma in Russia (BEST)
Benralizumab is a humanised, afucosylated, monoclonal antibody against the interleukin (IL)-5 receptor (IL-5R) α subunit that induces direct, rapid, and near-complete depletion of eosinophils in blood, airway tissue, and bone…
- Trial name
- NCT05271526
- Where
- Russia
- Volunteers
- 3 people
- Sponsor
- AstraZeneca
Inflammatory Bowel Disease, Inflammatory Bowel Disease (IBD)
Automated Clinical Pathway for Inflammatory Bowel Disease Care
Pragmatic randomized controlled trial to evaluate the effect of an electronic medical record-based tool on improving on-time follow up and its effects on inflammatory bowel disease outcomes
- Trial name
- NCT07167836
- Testing
- Electronic medical record-based care pathway
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Total Occlusion of Coronary Artery
Early and Midterm Outcomes of Intravascular Ultrasound (IVUS) Versus Non-IVUS Guidance in Complex Coronary Chronic Total Occlusion (CTO) Revascularization.
Various CTO percutaneous coronary intervention (PCI) studies defined CTO as as a substantial atherosclerotic blockage with >3 months duration of TIMI (Thrombolysis in Myocardial Infarction) 0 flow other than via collaterals.
- Trial name
- NCT04917432
- Testing
- intravascular ultrasound (IVUS), Conventional CTO PCI (non-IVUS guided)
- Volunteers
- 70 people
- Sponsor
- Assiut University
Diabetes Mellitus Type 2
Comparative Effectiveness of Cardiovascular Outcomes in New Users of SGLT-2 Inhibitors
CVD-REAL is a multinational, observational cohort study in patients with type 2 diabetes mellitus evaluating the comparative effectiveness of initiating treatment with a sodium-glucose co-transporter-2 (SGLT-2) inhibitor versus…
- Trial name
- CVD-REAL (NCT02993614)
- Where
- 17 sites in United States, Australia and 15 more
- Volunteers
- 99,999 people
- Sponsor
- AstraZeneca
Emotional Dysregulation
A Mightier Healthcare System
Access to effective pediatric mental health treatment is a major public health concern in the United States as paucity of pediatric providers leading to long wait times, financial burden, and stigma pose significant barriers to…
- Trial name
- NCT04732806
- Testing
- Mightier video games
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Neuromotion Labs
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.