Clinical trials: Upper Limb Disability
Elbow Stiffness, Elbow Pain
Comparative Effects of Mulligan Mobilization With and Without Myofascial Release Technique in Management of Post Traumatic Elbow Stiffness
The Randomize Clinical Trial will involve 30 participants with post traumatic elbow stiffness recruited from Madinah Teaching Hospital and Chiniot General hospital Faisalabad. Consecutive sampling technique will be used.
- Trial name
- NCT07598526
- Testing
- Group A (Mulligan Mobilization with Myofascial Release Technique), Group B (Mulligan Mobilization alone)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Learning Disorders, Specific, Learning Disabilities
Examining the Effect of a Digital Medical Device for Cognitive and Musical Training in Children With Reading Disabilities
The goal of this clinical trial is to assess the effect on reading skills of the digital medical device Poppins Clinical for cognitive and musical training in pediatric participants (ages 7-11) with a specific learning disability…
- Conditions
- Learning Disorders, Specific, Learning Disabilities, Specific Learning Disorder, With Impairment in Reading, Dyslexia
- Trial name
- POPPINS-CE (NCT06596980)
- Testing
- Poppins Clinical
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Poppins
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Down Syndrome
Effects of Task-oriented Training on Visual-motor Integration and Upper Limb Function in Children With Down Syndrome
The condition known as Down Syndrome (DS) is caused by trisomy 21, or the presence of an extra copy of chromosome 21. DS is the most common survivable autosomal aneuploidy and one of the genetically complicated problem compatible…
- Trial name
- NCT06943261
- Testing
- task oriented training, conventional therapy
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Cerebral Palsy, Upper Extremity Problem
Effects of Action Observation Therapy and Video-Based Play Therapy on Children With Unilateral Cerebral Palsy
Cerebral Palsy (CP) defines a group of permanent disorders in the development of movement and posture, which occur in the developing fetal and newborn brain, due to non-progressive disorders, leading to activity limitations.
- Trial name
- NCT05327179
- Testing
- Action Observation Treatment, Virtual Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sinem Erturan
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Prader-Willi Syndrome
A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone Injection in Patients With Prader-Willi Syndrome
To evaluate the effectiveness of rhGH (Recombinant human growth hormone) injection for improving motor development in patients with PWS.
- Trial name
- NCT03554031
- Testing
- Recombinant Human Growth Hormone (rhGH) Injection
- Where
- 6 sites in China
- Volunteers
- 30 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Ataxia, Spinocerebellar, Ataxias, Hereditary
Functional Trunk Training in Ataxia Patients
The study is to examine the effect of functional trunk training on trunk control and upper extremity functions in patients with autosomal recessive ataxia.
- Trial name
- NCT04740359
- Testing
- Functional training, Routine training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hasan Kalyoncu University
Stroke
SunRISe Study - Stroke Rehabilitation In Suriname
This study aims to determine the effect of a supervised home-based physical fitness program on the aerobic capacity, quality of gait and health related quality of life in people with chronic ischemic stroke.
- Trial name
- SunRISe (NCT02717715)
- Testing
- Home base stroke rehabilitation
- Where
- Suriname
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Hunter Syndrome
A Study of Elaprase in Children and Adults With Hunter Syndrome (Mucopolysaccharidosis II) in India
The main aim of this study is to learn more about the safety profile of Elaprase in Indian children and adults with hunter syndrome.
- Trial name
- NCT05058391
- Testing
- Elaprase
- Where
- 5 sites in India
- Volunteers
- 5 people
- Sponsor
- Takeda
Wheelchair Users, Athletic Performance
Vibration Therapy in Wheelchair Basketball Players
No study was found that investigated the effect of vibration therapy (VT) on recovery from exercise in WCB players. Therefore, the aim of the study was to investigate the effects of wearable local vibration device on muscle…
- Conditions
- Wheelchair Users, Athletic Performance, Disability, Disabled Persons
- Trial name
- NCT06403384
- Testing
- Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Karabuk University
Rett Syndrome
A Novel, Regulated Gene Therapy (NGN-401) Study for Females With Rett Syndrome
This study will evaluate the efficacy and safety profiles of the investigational gene therapy, NGN-401, in females with typical Rett syndrome.
- Trial name
- NCT05898620
- Testing
- NGN-401
- Where
- 16 sites in United States, Australia and 1 more
- Volunteers
- 33 people
- Sponsor
- Neurogene Inc.
Neuromuscular Disease, Neuromuscular Disability
The Effects of a Dynamic Arm Support in Daily Life
The goal of this mixed method study is to learn about how a dynamic arm support device (DAS) helps people with everyday activities. The study focuses on people with neuro(-muscular) conditions, age 16 and older.
- Conditions
- Neuromuscular Disease, Neuromuscular Disability, Assistive Technology, Activities of Daily Living
- Trial name
- NCT07121075
- Testing
- Dynamic arm support
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Hasselt University
Hunter Syndrome
Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment
Study HGT-HIT-094 is a multicenter study designed to determine the effect on clinical parameters of neurodevelopmental status of monthly IT administration of idursulfase-IT 10 mg for 12 months in pediatric patients with Hunter…
- Trial name
- AIM-IT (NCT02055118)
- Testing
- idursulfase-IT, No IT treatment
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 58 people
- Sponsor
- Shire
Specific Learning Disorder
Fine Motor Function in Children With Specific Learning Disorders
Specific Learning Disorder (SLD) is a neurodevelopmental disorder in which a person shows difficulties in reading, written narration, and/or mathematics.
- Trial name
- NCT05902143
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Scapular Dyskinesis
YWTL Exercises and Close Kinetic Chain Exercises in Children With Scapular Dyskinesis.
Scapular dyskinesia is defined by abnormal movement or placement of the scapula, the shoulder blade, during arm movements. Physical treatment aimed at regaining appropriate scapular mechanics through strengthening exercises…
- Trial name
- NCT06943131
- Testing
- YWTL EXERCISES, Closed kinetic chain exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Cerebral Palsy, Developmental Coordination Disorder
Bootle Blast: Understanding the Family Experience
One in 60 children have a physical disability that can impact activities and participation. Occupational and physical therapies can be of great benefit, but are costly and difficult to access.
- Conditions
- Cerebral Palsy, Developmental Coordination Disorder, Developmental Disability, Autism Spectrum Disorder
- Trial name
- NCT06161168
- Testing
- Bootle Blast Play Phase (B)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Mental Retardation, Upper Extremity
Effectiveness of Video Based Games on Upper Extremity Functions in Mild Mental Retardation Diagnosed Cases
With Leap Motion Controller, virtual reality exercises have been implemented more often since 2014, and this technology has benefited more from upper extremity rehabilitation In literature, there are no publications investigating…
- Trial name
- NCT03503955
- Testing
- Leap-Motion virtual reality games, fine motor skills activities
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Istanbul University
Upper Extremity Impairments, Cerebral Palsy (CP)
Obi Medical Robot: Evaluating Effectiveness Related to Usability
This mixed-methods usability study evaluates the effectiveness of the Obi Gen 3 robotic feeding device in meeting user needs among providers, caregivers, and patients.
- Conditions
- Upper Extremity Impairments, Cerebral Palsy (CP), ALS - Amyotrophic Lateral Sclerosis, Rett Syndrome
- Trial name
- NCT07151950
- Testing
- One-week trial of Obi Medical device, which provides robotic assistance with feeding to persons with upper extremity impairments who are unable to self-feed in the traditional manner using utensils
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Desin LLC
Disability Physical
Evaluation of ORTHOPUS Partner Arm in People With Disabilities Needing for Robotic Assistance to Compensate for Upper Limb Deficiency
The study is a prospective, multicenter, interventional, open clinical trial, in Single Case Experimental Design (SCED) in multiple introduction withdrawal, controlled, randomized.
- Trial name
- MS PARTNER (NCT06828510)
- Testing
- With device
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris