Clinical trials: VALİDİTY
Cerebral Palsy, Brain Injury
Validation of a 3D Instrumented Serious Game to Evaluate Upper Limb Impairments in Children With Neuromotor Disorders
The goal of this clinical trial is to validate an instrumented 3D serious game to assess upper limb impairments in children with neuromotor disorders.
- Conditions
- Cerebral Palsy, Brain Injury, Neurological; Disorder, Nervous System
- Trial name
- Play2BEAPI (NCT06774456)
- Testing
- instrumented 3D serious game (BE API 3.0)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Pregnancy Related
Chamas for Change Validation
This team has shown that chamas can be tailored to increase the uptake of health services in pregnancy and infancy, sustain themselves beyond the period of funding and become integrated within a county's health strategy.
- Trial name
- NCT03187873
- Testing
- Chama cha MamaToto
- Where
- Kenya
- Volunteers
- 3,040 people, healthy volunteers welcome
- Sponsor
- Moi University
Bronchiolitis
Pneumacare SLP Validation in Infants and in Clinical Bronchiolitis
A cohort observational study to characterise baseline Structured Light Plethysmography (SLP) outputs in infants with bronchiolitis and examine response to treatment using the Thora3DiTM
- Trial name
- NCT02881632
- Testing
- Structured Light Plethysmography (SLP) - Pneumscan
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
COVID-19
Bioaerosol Sampling Device (BSD) Clinical Study
The goal of this clinical trial is to learn about the bioaerosol sampling device (BSD) and how it can sample patient bioaerosols (breath) and patient's nares for the detection of COVID-19 viral particles in patients seeking to be…
- Trial name
- NCT06047067
- Where
- 6 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Cantor BioConnect, Inc.
Motor Disorders
Combined Artificial Intelligence and Mobile Application for Remote Infant Motor Screening: Development and Validation
The purpose of this study is therefore five-fold: (1) designation of an APP "Baby Go" version 3.0 to include the assessment, follow-up, and education functions for parental use at home, (2) development and validation of the AI…
- Trial name
- NCT06521918
- Where
- Taiwan
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Blood Pressure
Validation of a Noninvasive Automated Blood Pressure Device
The investigator's objective is to validate the novel automated blood pressure device against the requirements set forth in the AAMI_ISO 81060-2:2010 standard in voluntarily consented study participants.
- Trial name
- NCT03566888
- Testing
- Blood pressure assessment
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Depression
Diagnosis of Depression Among Adolescents
The objective of the study is to improve general practitioners' diagnoses of adolescent depression. Major depression is ranked fourth in the worldwide disability impact.
- Trial name
- NCT00443742
- Testing
- Validation
- Where
- Norway
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Ultrasonography
Detection of Muscle Quality in Children - Protocol for a Validation Study
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese…
- Trial name
- NCT06792279
- Where
- Czechia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Only Child, Balance, Postural
The Validity and Reliability of the Four Square Step Test
This study will evaluate concurrent and discriminative validity, reliability and level of agreement between the Timed Up \& Go test and the four square step test in typically developed children.
- Trial name
- NCT03693482
- Testing
- the Four Square Step test
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Quality Improvement
Testing the Reliability and Validity of the CIBA
The overall objective of the study is to improve the experience for pediatric patients undergoing anesthesia inductions. The specific objective for this proposal is to establish whether the CIBA tool demonstrates inter-rater…
- Trial name
- NCT02882594
- Testing
- Observing patient behaviors for anesthesia induction compliance
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pre-Term, Breast Milk Expression
Preemie Milk Analyser Validation Study
This study aims to test and validate the Preemie Ecosystem- a new device and associated software package for measuring the nutrient (fat, protein and carbohydrate) content of the breast milk of the mothers of premature babies.
- Conditions
- Pre-Term, Breast Milk Expression, Nutrition Disorder, Infant
- Trial name
- NCT06486194
- Testing
- Targeted breast milk fortification using preemie device, Standard Breast milk fortification
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Childhood Obesity
Shape Up Kids Fitness Ancillary
The overall objective of this study is to quantify the decision-making process and underlying biases around leisure activity behaviors using the Activity Preference Assessment (APA), a novel psychological task.
- Trial name
- NCT03624582
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Postural Tachycardia Syndrome
POTS NET mRNA Functional Correlation With NET Activity
DNA Acetylation can be responsible for significant down-regulation of transcription of the Norepinephrine Transporter (NET). NET is an important clearance transporter that removes norepinephrine (NE) from sympathetic neuronal…
- Trial name
- NCT03218761
- Testing
- NET mRNA level, Plasma catechols, Urine Catechols
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Adnexal Mass, Adnexal Tumor
Masses in Young Patients - International Ovarian Tumour Analysis (MY-IOTA)
This multicenter observational study aims to validate the IOTA Simple Rules, Benign Descriptors, and ADNEX model in a cohort of patients equal or under the age of 20.
- Conditions
- Adnexal Mass, Adnexal Tumor, Adnexal Cyst, Adnexal Masses in Young Girls and Adolescents
- Trial name
- MY-IOTA (NCT06693596)
- Testing
- Group 2: Conservative management (follow-up), Group 1: Surgical management
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lung Cancer, Breast Cancer
Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches.
- Conditions
- Lung Cancer, Breast Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT06363123
- Where
- 4 sites in China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Vision Impairment, Blindness
Assessment of the Validity, Reliability, and Feasibility of Two Smartphone Applications for Testing the Visual Acuity
Visual acuity (VA) is the most common measure of visual function globally. In clinical settings and during screening events, VA is an important measure to quantify changes in vision over time.
- Trial name
- NCT04936100
- Testing
- Assessment of distance and near visual acuity using "Vision Screening module" of "Easy Vision" application, Assessment of distance and near visual acuity using "Test Yourself module" of "Easy Vision" application, Assessment of distance and near visual acuity using "Peek Acuity" application
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Spina Bifida
QUALAS Validation in Dutch
Rationale Patients with spina bifida often experience a decreased quality of life compared to patients without spina bifida. The Quality of Life Assessment for Spina Bifida (QUALAS) is a validated questionnaire to assess the…
- Trial name
- NCT06723951
- Testing
- QUALAS survey
- Where
- 2 sites in Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Arthritis, Juvenile Idiopathic, Enthesitis-Related Arthritis, Juvenile
Juvenile Arthritis Quantitative Imaging
This observational study aims to develop and validate quantitative magnetic resonance imaging biomarkers as measures of disease activity in juvenile idiopathic arthritis (JIA).
- Trial name
- JAQI (NCT02684695)
- Testing
- MRI scan (adolescent spine protocol), MRI scan (whole body protocol)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Tropical Infectious Disease
Trained and Heterologous Induced-immune Responses to Tropical Infectious Diseases
Validation of ex vivo immune assays that are surrogates of complex in vitro assays and animal models studies to identify the occurrence, strength, and kinetics of trained and heterologous immunity may significantly impact public…
- Trial name
- TSH-IMMO (NCT05722054)
- Testing
- Diagnostic tests, Equilibrate diet
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Médicale de Lambaréné