Clinical trials: Validation
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Acute Appendicitis
Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT)
This retrospective observational study aims to compare the diagnostic accuracy of Alvarado Score, Appendicitis Inflammatory Response (AIR) Score, and Adult Appendicitis Score (AAS) in predicting histologically confirmed acute…
- Trial name
- DV-AAA ELHT (NCT07804238)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Heart Failure
Urdu Translation and Validation of MLHFQ
To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan. To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire…
- Trial name
- NCT06076447
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- Riphah International University
Musculoskeletal Pain, Questionnaire
The Turkish Version of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians (MPIIQM-T)
The aim of this study, original named "The musculoskeletal pain intensity and interference questionnaire (MPIIQM)" is the Turkish validation, reliability and cross-cultural validation of the questionnaire.
- Trial name
- NCT04785040
- Testing
- The groups evaluated by The Musculoskeletal Pain Intensity and Interference Questionnaire for Professional Orchestra Musicians, Brief Pain Inventory, QuickDASH and Fatigue Severity Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Ankara Yildirim Beyazıt University
Psoriasis
The PsoTeenQOL - Preliminary Reliability and Validity
This study aims to develop and provide preliminary reliability and validity of a questionnaire to measure Health-related Quality of Life (HRQOL) in adolescents with psoriasis.
- Trial name
- NCT03358914
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 233 people
- Sponsor
- University of Aarhus
Physical Activity, Children
Turkish Cultural Adaptation, Validity and Reliability Study of Youth Activity Profile
Aim: The aim of this study is to conduct a Turkish cultural adaptation, validity, and reliability study of the Youth Activity Profile (YAP), developed to assess physical activity and sedentary behavior in a sample of individuals…
- Trial name
- YAP-Turkey (NCT06466863)
- Testing
- Validity and Reliability
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Atopic Dermatitis, Food Allergies
Frequency of Food Allergy Confirm by Oral Food Challenge Among Foods Avoidance in Atopic Dermatitis Children
Atopic dermatitis can be caused by several factors, including food allergy. Currently, the diagnosis of food allergy often performing skin tests and measuring specific IgE foods that many studies have shown that about 53% of…
- Trial name
- NCT06947252
- Testing
- Oral food challenge test
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Cerebral Palsy
Urdu Version of Pediatric Balance Scale
Children with cerebral palsy often suffer from a lack of balance compared with typically developing children. Because balance capacity is relevant to functional activities, reliable and valid functional balance measures are…
- Trial name
- NCT04768049
- Testing
- Tool Translation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Labral Tear, Glenoid
Return to Play Checklist
This study will try to develop and determine objective and validated criteria for our athletes to safely return to sports after labral repair.
- Trial name
- NCT04278716
- Testing
- Safe return to play checklist
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Rothman Institute Orthopaedics
Tuberculosis, HIV
Validation of a Tuberculosis Treatment Decision Algorithm in HIV-infected Children (TB-Speed HIV)
TB-Speed HIV is a prospective multicentre management study evaluating the safety and feasibility of the recently proposed PAANTHER TB treatment decision algorithm for HIV-infected children with presumptive TB.
- Trial name
- NCT04121026
- Testing
- External validation of the PAANTHER TB treatment decision algorithm
- Where
- 7 sites in Côte d’Ivoire, Mozambique and 2 more
- Volunteers
- 278 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Type 1 Diabetes, Adolescent Development
Emoticare: Serious Game for the Adaptation to the Disease of Adolescents With Type 1 Diabetes Mellitus.
The intervention program targets adolescents with chronic Type 1 Diabetes Mellitus. Given the critical developmental stage and life transitions, necessitating robust personal resources, psychological support becomes imperative.
- Trial name
- NCT06331429
- Testing
- EmoTiCare
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of Valencia
Dysphagia, Esophageal, Esophageal Cancer
Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer
This study validates 3 well known dysphagia scores for dysphagia due to malignancies of the oesophagus and gastro-oesophageal junction and to the Swedish language.
- Trial name
- NCT03066167
- Testing
- Validation of different dysphagia scores
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Heavy Menstrual Bleeding
Evaluating the Reliability and Validity of the Arabic Version of the SAMANTA Questionnaire: A Step Toward Improved Diagnosis of Heavy Menstrual Bleeding
Heavy menstrual bleeding (HMB) significantly impacts women's quality of life (QoL). However, despite the high prevalence of HMB, culturally adapted screening tools remain scarce in our locality.
- Trial name
- NCT07267611
- Volunteers
- 120 people
- Sponsor
- Assiut University
CDKL5, CDKL5 Deficiency Disorder
International CDKL5 Clinical Research Network
Pathogenic variants in the Cyclin-dependent kinase like 5 (CDKL5) gene cause CDKL5 deficiency disorder (CDD, MIM 300672, 105830), a severe developmental and epileptic encephalopathy associated with cognitive and motor impairments…
- Conditions
- CDKL5, CDKL5 Deficiency Disorder, CDD
- Trial name
- ICCRN (NCT05558371)
- Testing
- No intervention.
- Where
- 9 sites in United States, Australia
- Volunteers
- 1,000 people
- Sponsor
- University of Colorado, Denver
Functional Gastrointestinal Disorders, Gastroparesis
Validation of a Mental Health Scale for Young People With Chronic Stomach Symptoms
This study aims to validate the Alimetry® Gut-Brain Wellbeing Survey- Youth Version (AGBW-Y), a mental health scale developed for patients aged 12-17 years with chronic stomach symptoms.
- Conditions
- Functional Gastrointestinal Disorders, Gastroparesis, Vomiting; Cyclical, Nausea
- Trial name
- NCT06394154
- Volunteers
- 100 people
- Sponsor
- Greg O'Grady
Trauma (Including Fractures)
Artificial Intelligence Algorithm for the Interpretation of Traumatic Bone Radiographs
This diagnostic study aims to compare the performance of an artificial intelligence (AI) algorithm designed to assist in the interpretation of traumatic bone radiographs (all anatomical regions excluding the thorax) with that of…
- Trial name
- AI-Traumat (NCT07329881)
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- Hôpital Universitaire Sahloul
Hospitalization, Neonatal Period
Hospitalizations in Neonatal Period and Early Discharge of Maternity
in the past 2 decades the number of early discharge of maternity is increasing. The aim of this study is to observe if an early maternity discharge increase the rate of hospitalization during the neonatal period.
- Conditions
- Hospitalization, Neonatal Period, Early Maternity Discharge, Risk Factor Readmission
- Trial name
- NCT05550272
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Dementia
Validation and Optimization of the Individual Benefits of Locating Systems in Dementia Care
The project aims to make new technologies for locating people with dementia easier to use for the patients and those caring for them.
- Trial name
- VODINO (NCT02893800)
- Testing
- Locating system watch with GPS-technology
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Bowel Dysfunction, Dysmotility
Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children
The goal of this clinical trial is to learn if the new non-invasive device (Body Surface Colonic Mapping) works to accurately assess colonic movement and function in children.The main questions it aims to answer are: Are Body…
- Conditions
- Bowel Dysfunction, Dysmotility, Hirschsprung Disease, Anorectal Malformations
- Trial name
- NCT07789782
- Testing
- Body Surface Colonic Mapping
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
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