Clinical trials: Validity
Esophageal Cancer
Quality-of-Life Assessment of Patients Who Have Cancer of the Esophagus
RATIONALE: Questionnaires that measure quality of life may improve the ability to plan treatment for patients who have cancer of the esophagus.
- Trial name
- NCT00003321
- Testing
- psychosocial assessment and care, quality-of-life assessment
- Where
- 10 sites in Australia, France and 6 more
- Volunteers
- 370 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Heavy Menstrual Bleeding
Evaluating the Reliability and Validity of the Arabic Version of the SAMANTA Questionnaire: A Step Toward Improved Diagnosis of Heavy Menstrual Bleeding
Heavy menstrual bleeding (HMB) significantly impacts women's quality of life (QoL). However, despite the high prevalence of HMB, culturally adapted screening tools remain scarce in our locality.
- Trial name
- NCT07267611
- Volunteers
- 120 people
- Sponsor
- Assiut University
Influenza
Collection and Extraction of Respiratory Specimens
The study will be conducted with nasopharyngeal swab specimens collected prospectively from individuals suspected of having an acute respiratory tract infection caused by an Influenza virus.
- Trial name
- NCT01083511
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- QIAGEN Gaithersburg, Inc
Developmental Delay, Child Development
Validity and Reliability of Indonesian Translated Ages and Stages Questionnaires - Third Edition (ASQ-3) as a Screening Tool for Developmental Delay in 1-12 Months Old Children
This study aimed to provide the validity and reliability of the Indonesian ASQ-3 questionnaires as a screening tool for developmentally delayed children aged less than one year old. This study was divided into 2 phases.
- Conditions
- Developmental Delay, Child Development, Child Development Disorder, Global Developmental Delay
- Trial name
- NCT05398900
- Where
- Indonesia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Stroke
Turkish Validity and Reliability of the Expanded Rehabilitation Complexity Scale
The RCS is a tool that can assess the need for complex rehabilitation and objectively indicate that a patient may have difficulty functioning well at home or in the community if their medical needs are still high.
- Trial name
- NCT06573359
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Hepatocellular Carcinoma (HCC)
Precision Recurrence Risk Assessment in Early-stage Hepatocellular Carcinoma
This retrospective observational study aims to evaluate whether artificial intelligence (AI) models can predict aggressive recurrence in patients who underwent liver resection for early-stage hepatocellular carcinoma (HCC).
- Trial name
- NCT07030842
- Testing
- liver resection
- Where
- China
- Volunteers
- 579 people
- Sponsor
- Tongji Hospital
Cytomegalovirus, Kidney Transplantation
Clinical Validation of Lophius Biosciences Kit T-Track® CMV in Kidney Transplant Recipients
This study aims to validate whether Lophius Biosciences Kit T-Track® CMV is suitable to assess the functionality of CMV-specific cell-mediated immunity (CMI) and to determine a protective cut-off value for CMV…
- Conditions
- Cytomegalovirus, Kidney Transplantation, CMV Specific Immune Response
- Trial name
- CMValue (NCT02083042)
- Where
- Germany
- Volunteers
- 97 people
- Sponsor
- Lophius Biosciences GmbH
Absence Seizures, Absence Epilepsy
ECV - Epihunter Clinical Validation
The goal of this prospective study is to validate a wearable EEG seizure detection solution compared to video EEG. Subjects that undergo a clinical video EEG are asked to additionally wear a wearable EEG headband for up to 2…
- Trial name
- ECV (NCT04615442)
- Testing
- Epihunter
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 102 people
- Sponsor
- Epihunter NV
Matched-Pair Analysis, Blood Gas Analysis
Mathematical Arterialization of Venous Blood Gas
Objective: Arterial blood gas (ABG) analysis is essential in the clinical assessment of potential acutely ill patients. Venous to arterial conversion (v-TAC), a mathematical method, has recently been developed to convert…
- Conditions
- Matched-Pair Analysis, Blood Gas Analysis, Emergency Service, Hospital
- Trial name
- NCT03309410
- Testing
- Venous to arterial conversion (v-TAC)
- Volunteers
- 30 people
- Sponsor
- Aalborg University
Ultrasonography, Coronal
Validity and Reliability of Ultrasound Imaging for Measuring Coronal and Sagittal Angles in Idiopathic Scoliosis
Patients with idiopathic scoliosis (IS), especially children and adolescents, require regular follow-up evaluations. Ultrasound imaging offers a reliable, radiation-free method for assessing spinal curvatures in the coronal and…
- Conditions
- Ultrasonography, Coronal, Sagittal, Idiopathic Scoliosis
- Trial name
- NCT06510049
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
The Initial Aim of This Project is to Perform in Vitro Validation of Neoepitope Candidates Selected From Available Mutanome Data
Identification of Immunogenic Neo-epitopes for the Development of Personalised Pancreatic Cancer Vaccines
Human pancreatic cancer has a very poor prognosis with an overall survival rate of less than 5%. Current treatment regimens are ineffective and even if the patient responds to initial treatments, relapse is common due to the…
- Trial name
- CanVac (NCT04379960)
- Testing
- Peptides
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Type 2 Diabetes, Chronic Disease
Prevention Strategies for Adolescents at Risk of Diabetes
The primary aim of PRE-STARt Phase 1 is to pragmatically evaluate and refine a risk assessment tool to identify those children with chronic disease risk factors (including Type 2 Diabetes).
- Trial name
- PRE-STARt (NCT02545140)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Sleep Disorder, Autism Spectrum Disorder
Development and Validation of a Comprehensive Module for Management of Sleep Disorders in ASD Children
Sleep disorder in autism children is common and it affects the physical, behavior and mental health. There is lack of comprehensive management program/module to treat the sleep disorders in children with ASD.
- Conditions
- Sleep Disorder, Autism Spectrum Disorder, Polysomnography, Actigraphy
- Trial name
- NCT06260020
- Testing
- Comprehensive module for management of sleep disorders[Behavioral and pharmacological therapy]
- Volunteers
- 25 people
- Sponsor
- All India Institute of Medical Sciences
ThermoSpot Accuracy and Maternal Recognition
Evaluation of Thermospot Accuracy in Nigerian Infants Exposed to Ambient Temperature and Validation of Maternal Readings and Responses
This project will focus on testing the accuracy of ThermoSpot -a low-cost, color-based, temperature indicator in estimating the body temperature of Nigerian babies exposed to ambient temperature conditions.
- Trial name
- Thermospot (NCT02968524)
- Where
- Uganda
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Difficult Biliary Cannulation
A Convolutional Neural Network for Difficult Biliary Cannulation
The main purpose of the study is to train a convolutional neural network (CNN) to predict difficult biliary canulation (DBC) following the European Society of Gastrointestinal Endoscopy Society (ESGE).
- Trial name
- PRECABIDO2 (NCT07389915)
- Testing
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Volunteers
- 600 people
- Sponsor
- University of La Laguna
Mantle Cell Lymphoma, Chronic Lymphocytic Leukaemia
Tissue Collection for Biomarkers Determining Resistance to Ibrutinib
Clinical validation of biomarkers determining resistance to BTK inhibition with Ibrutinib in Mantle Cell Lymphoma and Chronic Lymphocytic Leukaemia Stage 1.
- Trial name
- CLARITY (NCT02267590)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Musculoskeletal Diseases
Competency-based Assessment in Musculoskeletal Ultrasound
Early diagnosis and rapid treatment initiation are of most importance to prevent joint damage in patients with arthritis. Musculoskeletal ultrasound (MSUS) is becoming an integrated part of rheumatology routine care and is more…
- Trial name
- NCT05256355
- Testing
- musculoskeletal ultrasound
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Treatment Outcome, Muscle Dystonia
Quantifying Muscle Tone in Patients With Brain Injury - a Feasibility Study
This project will determine the feasibility and validity of measuring elbow muscle flexor stiffness in a population of patients with sub-acute severe acquired brain injury using two measurement methods, the portable spasticity…
- Conditions
- Treatment Outcome, Muscle Dystonia, Spasticity, Muscle, Muscle Tightness
- Trial name
- NCT04207632
- Testing
- Botulinum toxin type A injection
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autism Spectrum Disorder
Psychometric Validation of the Camouflaging Autistic Traits Questionnaire
For many affected individuals, despite impairment and distress, autism spectrum disorder (ASD) is recognized and diagnosed late, in school age, adolescence, or even in adulthood, which could be due, among other things, to the use…
- Trial name
- CAT-Q/DE (NCT05989685)
- Where
- Germany
- Volunteers
- 622 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Down Syndrome
Turkish Adaptation of Segmental Assessment of Trunk Control Scale
In infants with Down syndrome at risk in terms of neurosensory motor development retardation, the level of trunk control can determine the level of trunk control towards motor development in infants with down syndrome.
- Trial name
- NCT04657276
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Hacettepe University
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