Clinical trials: Validity
Emergencies
Forecasting ED Overcrowding With Statistical Methods: A Prospective Validation Study
The aim of this study is to prospectively validate statistical forecasting tools that have been widely used retrospectively in forecasting ED overcrowding
- Trial name
- NCT05174481
- Testing
- Early warning system for emergency department overcrowding
- Volunteers
- 160,000 people
- Sponsor
- Tampere University Hospital
Cryptococcosis, Lung Adenocarcinoma
Derivation and Validation of a Scoring System to Distinguish Cryptococcosis and Adenocarcinoma in Pulmonary Nodules
Pulmonary cryptococcosis often manifests as isolated or multiple nodules, easily mimicking lung cancer clinically and radiologically, which ascribes the poor sensitivity of Cryptococcus culture and rarely positive of Cryptococcal…
- Trial name
- NCT04554875
- Testing
- A scoring system
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Cholangiopancreatography, Endoscopic Retrograde, Simulation Training
Fast-tracking ERCP Learning: Does Training on a Mechanical Simulator Improve Trainee's Clinical Performance?
The hypothesis of this study is that novice trainees who are offered early simulation training in Boškoski-Costamagna ERCP Trainer in addition to routine hands-on training (intervention group) will demonstrate improved clinical…
- Trial name
- NCT05533944
- Testing
- Simulation training in Boškoski-Costamagna ERCP Trainer
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Functional Movement Disorders, Reproducibility of Results
Aspects of Validity of the Single Leg Squat Test: A Cohort Study of Female Soccer Players.
Movement screening tests to identify deficits or poor movement quality is commonly used in soccer and other sports to assess injury, to evaluate rehabilitation goals and return to sport after injury.
- Conditions
- Functional Movement Disorders, Reproducibility of Results, Sports Medicine
- Trial name
- NCT05289284
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Lutein and Zeaxanthin Dietary Intake, Age Related Macular Degeneration
Online Validation of Dietary Intake Food Frequency Questionnaire Over Four Weeks, and Electronic Device Use Questionnaire Over Eight Weeks.
Tools to investigate dietary lutein and zeaxanthin (L/Z) intake and electronic device (ED) use are important to progress research that investigates the role of ED blue light (BL) exposure, and dietary L/Z intake on macular…
- Conditions
- Lutein and Zeaxanthin Dietary Intake, Age Related Macular Degeneration, Blue Light Exposure, Electronic Device Use
- Trial name
- NCT04779411
- Testing
- Weekly Food Frequency Questionnaire, Monthly Food Frequency Questionnaire, 24-Hour Diet Recall
- Where
- Australia
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Traumatic Brain Injury, Cerebral Palsy
Validity and Reliability of Perceived Exertion Rating Scale in Children With Brain Damage
The purpose of this study is to examine the reliability and validity of the rating of perceived exertion scale in children post severe traumatic brain injury during treadmill exercise.
- Trial name
- NCT01840644
- Testing
- Walking on treadmill, different velocities and incline
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
MASLD, Pediatric
Ultrasound-Based Estimation of Hepatic Steatosis in Pediatric MASLD
The purpose of this study is to validate an artificial intelligence (AI)-based algorithm that estimates hepatic steatosis using ultrasound (US) B-mode images in pediatric participants with metabolic dysfunction-associated…
- Trial name
- NCT07265011
- Testing
- Ultrasound and MRI
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jae Won Choi
Severe Infection
Validation of the Quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) in Obstetric Patients
Research problem: In 1991, the terms Systemic Inflammatory Response Syndrome (SIRS), severe sepsis, and septic shock were introduced, based on the pro-inflammatory theory, conforming to a list of classification criteria for each…
- Trial name
- COLOSSAL (NCT04621539)
- Where
- Colombia
- Volunteers
- 2,125 people
- Sponsor
- Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia
Acute Kidney Injury, Mechanical Ventilation
Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy
The goal of the BRAVE-HEART study is to learn if an amino acid infusion can reduce the risk of developing acute kidney injury after cardiac surgery in children. The main questions it aims to answer are: 1.
- Trial name
- BRAVE-HEART (NCT07212595)
- Testing
- Amino Acid infusion, Lactated ringers solution
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana Fuhrman
Ovarian Neoplasms, Ovarian Cancer
Prospective Sample Collection Study for a Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection
The goal of this observational study is to learn whether a blood-based cell-free DNA (cfDNA) methylation assay can help detect ovarian cancer, especially early-stage ovarian cancer, in women undergoing clinical evaluation for…
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Early Detection of Cancer
- Trial name
- NCT07593833
- Testing
- Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Malocclusion
Evaluation of the Accuracy of Measurements Made on Images Taken From the Mouth for Dental Arches
The general trend in the orthodontic practice is to become digital in many aspects. Since 1980s, digital photographs have been available and they play a principal role in the orthodontic practice for documentation and diagnosis…
- Trial name
- NCT03648515
- Testing
- Plaster models, Digital Images of the dental arches, Digital images of models
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Fever
SCT02 Clinical Accuracy Validation
The aim of the study is to validate the accuracy of the temporal thermometer of Withings SCT02
- Trial name
- WIBOFE (NCT06637878)
- Testing
- Investigational Device (Withings SCT02) temporal thermometer measurement, Reference Device (Withings SCT01) temperature measurement
- Where
- 5 sites in United States
- Volunteers
- 118 people
- Sponsor
- Withings
Child Development, Physical Disability
Children Participation Assessment Scale
Increasing the number of Turkish versions of questionnaires evaluating participation will increase the variety of assessment methods.
- Conditions
- Child Development, Physical Disability, Participation, Patient
- Trial name
- NCT05107518
- Testing
- Children Participation Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gazi University
Functional Gastrointestinal Disorders, Gastroparesis
Validation of a Mental Health Scale for Young People With Chronic Stomach Symptoms
This study aims to validate the Alimetry® Gut-Brain Wellbeing Survey- Youth Version (AGBW-Y), a mental health scale developed for patients aged 12-17 years with chronic stomach symptoms.
- Conditions
- Functional Gastrointestinal Disorders, Gastroparesis, Vomiting; Cyclical, Nausea
- Trial name
- NCT06394154
- Volunteers
- 100 people
- Sponsor
- Greg O'Grady
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Substance Withdrawal Syndrome
Validation of a Pediatric-Specific Abstinence Syndrome Assessment Tool
The purpose of this study is to assess the validity and reliability of an abstinence syndrome assessment tool used in pediatric patients with iatrogenic opioid dependence.
- Trial name
- NCT00792415
- Where
- United States
- Sponsor
- Banner Health
Infant Behavior
Validation of Active-Insights Device to Measure Crying Time
To assess the ability of a machine learning algorithm to accurately detect fussing and crying time in infants using accelerometery data collected from a wearable device, compared to the Barr's parent-/caregiver-completed…
- Trial name
- NCT05165589
- Testing
- ActiveInsights accelerometer device
- Where
- Ireland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Exclusive Breastfeeding, Human Milk
Assessing Exclusive Breastfeeding Practice
This study was a longitudinal design. The questionnaire on exclusive breastfeeding was administered and was validated against the deuterium oxide dose-to-mother technique to assess human milk intake of babies aged 3 and 6 mo.
- Conditions
- Exclusive Breastfeeding, Human Milk, Breast Milk
- Trial name
- NCT05959460
- Testing
- Deuterium dose-to-mother method for assessing breastfeeding
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Chronic Pain
Analgesia Nociception Index In Pediatric Patients With Chronic Pain
The goal of this observational study is to learn about the analgesia nociceptive index (ANI) is associated with pain sensitivity in patients between the ages of 9-17 who are experiencing chronic pain.
- Trial name
- Chronic pain (NCT07145762)
- Testing
- Interventional Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Pruritus
Study of Kids Itch Severity (SKIS)
This purpose of this study is to validate two measures of chronic itching in kids: itch severity (ItchyQuant) and the impact on their quality of life (ItchyQoL).
- Trial name
- SKIS (NCT02672579)
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Emory University
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