Clinical trials: Validity, open to volunteers
Cerebral Palsy, Brain Injury
Validation of a 3D Instrumented Serious Game to Evaluate Upper Limb Impairments in Children With Neuromotor Disorders
The goal of this clinical trial is to validate an instrumented 3D serious game to assess upper limb impairments in children with neuromotor disorders.
- Conditions
- Cerebral Palsy, Brain Injury, Neurological; Disorder, Nervous System
- Trial name
- Play2BEAPI (NCT06774456)
- Testing
- instrumented 3D serious game (BE API 3.0)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Prostate Cancer
Prostate Cancer IMAGing IN Early Detection (IMAGINED Trial)
The researchers hope to learn if specific types of MRI software and techniques can help improve early prostate cancer detection at time of a MRI-guided prostate biopsy.
- Trial name
- IMAGINED (NCT05882253)
- Testing
- Restricted Spectrum Imaging-Magnetic Resonance Imaging (RSI-MRI)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of California, San Diego
Adolescence Idiopathic Scoliosis
Validity and Reliability of the Behavioral Regulation in Exercise Questionnaire-2 (BREQ-2) in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a spinal condition that develops during adolescence and often requires long-term conservative treatment, including scoliosis-specific therapeutic exercises.
- Trial name
- NCT07359781
- Testing
- Questionnaire Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Nigde Omer Halisdemir University
Allergy
LOGOGRAM: Validation of Allergy Care Flowcharts in Primary Care: Experience From Occitanie
This study, aimed at validating decision trees developed through collaboration between general practitioners and allergists, seeks to provide French data to optimize care pathways for patients with allergic diseases from the…
- Trial name
- LOGOGRAM (NCT07631039)
- Testing
- Implementation of an innovative tool based around AI-automated decision trees on an application
- Where
- 10 sites in France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Montpellier
Motor Disorders
Combined Artificial Intelligence and Mobile Application for Remote Infant Motor Screening: Development and Validation
The purpose of this study is therefore five-fold: (1) designation of an APP "Baby Go" version 3.0 to include the assessment, follow-up, and education functions for parental use at home, (2) development and validation of the AI…
- Trial name
- NCT06521918
- Where
- Taiwan
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ultrasonography
Detection of Muscle Quality in Children - Protocol for a Validation Study
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese…
- Trial name
- NCT06792279
- Where
- Czechia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Hospitalized Patients
Cultural Adaptation, and Validation of Fundamentals of Care PRO-tool
A research team from the University of Seville and Flinders University has created a new 41-item questionnaire to assess fundamental nursing care.
- Trial name
- NCT07042880
- Testing
- No intervention
- Where
- 2 sites in Denmark
- Volunteers
- 205 people
- Sponsor
- Nordsjaellands Hospital
Electrolyte Disorder, Arrhythmia
Validation of the Accuracy of a Novel POCT Dry Electrolyte Analysis System in the Acute Care Setting
The goal of this study is to compare the performance of a novel Point-of-Care Testing (POCT) dry electrolyte analyzer (P1) with the Nova Stat Profile pHOx Ultra Analyzer System (Nova) in an acute care setting.
- Conditions
- Electrolyte Disorder, Arrhythmia, Stroke
- Trial name
- NCT06726460
- Testing
- Nova Stat Profile pHOx Ultra Analyzer System(Nova), Novel POCT dry electrolyte analysis system(P1)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhujiang Hospital
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Chronic Pain
Analgesia Nociception Index In Pediatric Patients With Chronic Pain
The goal of this observational study is to learn about the analgesia nociceptive index (ANI) is associated with pain sensitivity in patients between the ages of 9-17 who are experiencing chronic pain.
- Trial name
- Chronic pain (NCT07145762)
- Testing
- Interventional Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Neonatal Late Onset Sepsis
Validation of Biomarkers Performance to Reduce Antibiotics overUse in newBorns With Suspected Clinical Signs of InfectionS
Late-onset neonatal sepsis (LOS), occurring in newborn of at least 7 days of life, is frequently observed in Neonatal Intensive Care Units (NICUs) and potentially severe (mortality, neurologic and respiratory impairments).
- Trial name
- RUBIS (NCT06058819)
- Testing
- Newborns suspected of Infections
- Where
- 3 sites in France
- Volunteers
- 285 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Diseases
Validation, Implementation, and Cost-analysis of a Strategy for Personalized Diagnosis of Rare Kidney Diseases
Chronic kidney disease (CKD) affects about 10% of the world population, with high morbidity and mortality. Genetic kidney diseases are increasingly recognized across all age groups and represent over 20% of all the causes of CKD.
- Trial name
- NCT06324136
- Testing
- Implementation of the diagnostic algorithm
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS
Spina Bifida
QUALAS Validation in Dutch
Rationale Patients with spina bifida often experience a decreased quality of life compared to patients without spina bifida. The Quality of Life Assessment for Spina Bifida (QUALAS) is a validated questionnaire to assess the…
- Trial name
- NCT06723951
- Testing
- QUALAS survey
- Where
- 2 sites in Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Validation Studies, Psychiatric Diagnosis
Digitizing and Automating the Diagnostic Psychiatric Assessment Process
This is an observational study that will be responsible for the Spanish translation and cross-cultural adaptation, and validation of the Electronic Semi-Structured Psychiatric Interview for Children and Adolescents (EPSI-C), to…
- Trial name
- DADAP (NCT07468214)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Irene Lopez Armenteros
Spinal Cord Injuries (SCI)
Turkish Translation and Content Validity of the Nottwil Environmental Factors Inventory (NEFI) in Persons With Spinal Cord Injury
This observational methodology study will produce a Turkish version of the Nottwil Environmental Factors Inventory (NEFI-TR) within one month using a standardized translation and cultural adaptation process.
- Trial name
- NCT07368244
- Where
- Turkey (Türkiye)
- Volunteers
- 405 people
- Sponsor
- Istanbul Medeniyet University
Atopic Dermatitis, Food Allergies
Frequency of Food Allergy Confirm by Oral Food Challenge Among Foods Avoidance in Atopic Dermatitis Children
Atopic dermatitis can be caused by several factors, including food allergy. Currently, the diagnosis of food allergy often performing skin tests and measuring specific IgE foods that many studies have shown that about 53% of…
- Trial name
- NCT06947252
- Testing
- Oral food challenge test
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Attention Deficit Hyperactivity Disorder Combined
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due to problems with attention and high levels of impulsivity and…
- Trial name
- AMPAIII (NCT04421248)
- Testing
- Methylphenidate
- Where
- 2 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Donald Gilbert, MD, MS, FAAN, FAAP
Thyroid Diseases, Thyroid Neoplasms
Computer Vision-Based Recognition of Parathyroid Glands and Recurrent Laryngeal Nerves in Endoscopic Surgery
This study aims to evaluate the performance of the PTAIR computer vision model for recognizing parathyroid glands and recurrent laryngeal nerves during endoscopic thyroid surgery.
- Trial name
- PTAIR (NCT07628543)
- Testing
- PTAIR Computer Vision Model Assessment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Anemia
NeoSpHb Study: Can a Painless Device Detect Anaemia in Babies Without Blood Tests? A Study in the Neonatal Intensive Care Unit (NICU)
The goal of this study is to evaluate the diagnostic performance and feasibility of non-invasive spectrophotometric haemoglobin (SpHb) measurement for detecting anaemia in infants admitted to the Neonatal Intensive Care Unit…
- Trial name
- NeoSpHb (NCT07788703)
- Testing
- Spectrophotometry hemoglobin
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Endodontic Retreatment, Non-surgical Retreatment
Development and Validation of a Deep Learning Model to Predict Endodontic Retreatment Difficulty From Periapical Radiographs
The aim of this study is to develop and evaluate an artificial intelligence-based model capable of analyzing periapical radiographs of maxillary and mandibular molars to predict the difficulty level of non-surgical root canal…
- Conditions
- Endodontic Retreatment, Non-surgical Retreatment, Endodontics, AI (Artificial Intelligence)
- Trial name
- Ai Retreatment (NCT07611279)
- Testing
- Deep Learning Model to Predict Endodontic Retreatment Difficulty from Periapical Radiographs
- Volunteers
- 123 people
- Sponsor
- Cairo University