Clinical trials: Variability
Sleep Initiation and Maintenance Disorders, Anxiety
HIRREM Developmental Study
The purpose of this study is to explore the functional and physiological effects associated with the use of High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), as supplemental care, for symptoms of…
- Conditions
- Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes
- Trial name
- NCT02709369
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Type 1 Diabetes
Blood Glucose Variability and Insulin Action During Menstrual Cycle in Females With Type 1 Diabetes
This research study is designed to look at differences in responsiveness to the subcutaneous injection of a standardized dose of rapid-acting insulin analog and blood glucose variability during different phases of the menstrual…
- Trial name
- NCT02693938
- Testing
- Follicular Euglycemic clamp, Luteal Euglycemic clamp
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Yale University
Neuromotor Impairments
AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients: A Pilot Study
What is the purpose of this study? This study aims to evaluate the usability and feasibility of an artificial intelligence-based model designed to monitor in real-time the engagement and motor performance of pediatric patients…
- Trial name
- AI-REMAP (NCT07664033)
- Testing
- Artificial Intelligence Model for Rehabilitation Engagement Monitoring
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Eugenio Medea
Congenital Heart Disease, Dysbiosis
The Influence of Probiotics on Metabolome and Heart Rate Variability in Heart Failure of Structure Heart Disease
Poor body weight gain and failure to thrive is a very common condition in patients with congenital heart disease (CHD) with advanced HF and/or cyanosis, which are considered a predictor of morbidity and complicate the prognosis…
- Conditions
- Congenital Heart Disease, Dysbiosis, Malnutrition, Child, Probiotics
- Trial name
- NCT06872320
- Testing
- Lactobacillus Rhamnosus
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Attention-Deficit/Hyperactivity Disorder (ADHD)
Does Active Parent Involvement in Deliberation and Choice Improve Medication Persistence for Their Child With ADHD
The purpose of the study is to determine whether active parent involvement in deliberation and choice improves subsequent medication persistence for their child with ADHD.
- Trial name
- NCT00631280
- Testing
- Choice, Recommendation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Central Blood Pressure, Obesity
Blood Pressure and Central Vascular Stiffness in Obese Children. Relationship to Metabolic Disturbances and Subclinical Cardiovascular Damage. Effect of Weight Reduction
The global epidemic of obesity in childhood continues to evolve and threaten future health and life expectancy primarily due to the increased incidence of cardiovascular disease.
- Conditions
- Central Blood Pressure, Obesity, Subclinical Organ Damage, Children
- Trial name
- AORTA (NCT01310088)
- Testing
- Lifestyle intervention
- Where
- 2 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Heart Rate Variability
Exploring HRV in Antarctic Overwintering Members of Asia
Extreme changes in the Antarctic environment can cause emotional and autonomic dysfunction. In this study, volunteers from the Antarctica stations in China provided scale scores and heart rate variability (HRV) data, which were…
- Trial name
- NCT06385782
- Testing
- Antarctic environment
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ya-Wei Xu
Chronic Fatigue Syndrome
A Rehabilitation Program for Adolescents With Chronic Fatigue Syndrome
The aim of the programme is to develop a treatment model for adolescents with Chronic Fatigue Syndrome. The program consists of 4 elements lasting for 12 months, psychoeducation reflecting the current knowledge about the disease…
- Trial name
- NCT01806246
- Testing
- integrative rehabilitation program
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- St. Olavs Hospital
Vomiting Syndrome, Irritable Bowel Syndrome
Autonomic Profiles in Pediatric Patients With Cyclic Vomiting Syndrome (CVS), Irritable Bowel Syndrome (IBS),Postural Orthostatic Tachycardia Syndrome (POTS), Functional Abdominal Pain (FAP) or Chronic Nausea
Retrospectively review the charts of all children who had heart rate variability, deep breathing test, valsalva maneuver, tilt table test, thermoregulatory sweat testing, quantitative sudomotor axon reflex test (QSART) completed…
- Conditions
- Vomiting Syndrome, Irritable Bowel Syndrome, Postural Orthostatic Tachycardia Syndrome, Abdominal Pain
- Trial name
- NCT00728026
- Volunteers
- 19 people
- Sponsor
- Medical College of Wisconsin
Dysautonomia, Familial, Baroreflex Failure Syndrome
Carbidopa for the Treatment of Excessive Blood Pressure Variability
The overall study objectives are to determine whether carbidopa (Lodosyn®) is safe and well tolerated and to assess whether it can inhibit catecholamine-induced paroxysmal hypertension and normalize or reduce the exaggerated…
- Trial name
- CarbiFD (NCT02553265)
- Testing
- Carbidopa Low-Dose, Carbidopa High-Dose
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis (RA
Effects of Chronic Non-invasive Vagus Nerve Stimulation in an Asplenic Individual Suffering From Rheumatoid Arthritis
The goal of this clinical trial is to learn if chronic self-administrated non-invasive vagus nerve stimulation works to improves the disease activity in a single asplenic patient suffering from rheumatoid arthritis.
- Trial name
- NCT07646470
- Testing
- Trans-auricular vagus nerve stimulation
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Osteoflow Health Clinic
Bronchiolitis, Bronchiolitis Acute Viral
Analysis of Variability in the Management of Respiratory Infections in Hospitalized Patients Under 2 Years of Age
Medical practice variability refers to differences in treatment and clinical outcomes that cannot be solely explained by patient characteristics or medical conditions.
- Trial name
- NCT07202585
- Where
- Argentina
- Volunteers
- 127 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Type 1 Diabetes, Continuous Glucose Monitoring
The Effect of Frequent Continuous Glucose Monitoring Use on Glucose Variability in Preschoolers With Type 1 Diabetes
The purpose of this study is to determine whether continuous glucose monitoring will improve glucose variability as measured by the coefficient of variation of glucose levels in very young children with T1D.
- Conditions
- Type 1 Diabetes, Continuous Glucose Monitoring, Children, Glucose Variability
- Trial name
- NCT04558710
- Where
- Slovenia
- Volunteers
- 339 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Step Time and Length, Symmetry
The Contribution of Heels for Walking Quality Among Children With Muscular Dystrophy
During the stand phase the DMD foot is too plantarflexed in addition patients adopt a higher flexion and abduction of the hip in order to advance the swinging limb.
- Conditions
- Step Time and Length, Symmetry, Step Time and Length Variability, Heart Rate
- Trial name
- NCT01638169
- Testing
- adding a heel
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Immaturity, Oral Intolerance
Effect of Kangaroo Care on Heart Rate Variability
Physiological processes leading to a preterm infant to be able to feed orally has not been fully understood. The investigators hypothesized that maturation of autonomic nervous system may play a major role in this process and…
- Conditions
- Immaturity, Oral Intolerance, Postnatal Adaptation
- Trial name
- NCT01865409
- Testing
- Kangaroo Care
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih University
Pneumothorax
Heart Rate Variability in Pneumothorax
Changes in heart rate variability in anesthetized, ventilated patients undergoing tension pneumothorax for thoracoscopic cervical sympathectomy
- Trial name
- NCT03537417
- Testing
- for thoracoscopic ablation of cervical sympathetic chain
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Attention-deficit/Hyperactivity Disorder, Autonomic Nervous System Imbalance
Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy.
Obstructive sleep apnea (OSA) and attention-deficit/hyperactivity disorder (ADHD) are two common, severe disorders in children. Unfortunately, pediatric OSA is closely associated with ADHD, and both diseases can cause cognitive…
- Conditions
- Attention-deficit/Hyperactivity Disorder, Autonomic Nervous System Imbalance, Obstructive Sleep Apnea of Child
- Trial name
- NCT04732572
- Testing
- Sleep and healthy lifestyle education, Other supportive care, Adenotonsillectomy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Circulatory Failure
NeoAdapt 3: Novel Biomarkers in the Evaluation of Neonatal Circulatory Insufficiency in Babies Suffering From Hypoxic Ischemic Encephalopathy
1 in 1000 babies are born suffering from a lack of oxygen. This is known as hypoxic ischemic encephalopathy (HIE). Infants with this condition can suffer multiple organ problems.
- Trial name
- NCT02051894
- Testing
- Dobutamine
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Craniosynostosis
Pleth Variability Index Monitoring in Pediatric Craniosynostosis Surgery
This prospective observational study aims to evaluate the role of pleth variability index (PVI) and perfusion index (PI) monitoring in intraoperative hemodynamic control among pediatric patients undergoing craniosynostosis…
- Trial name
- PVI-CRANIO (NCT07657598)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Muzaffer GENCER
Primary Dysmenorrhea
Rhythmical Massage Compared With Heart Rate Variability Biofeedback in Women With Menstrual Pain (Dysmenorrhea)
A study to explore whether rhythmical massage and heart rate variability biofeedback can help to reduce pain in women suffering from menstrual pain (dysmenorrhea).
- Trial name
- NCT03712800
- Testing
- Rhythmical massage, HRV biofeedback
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine