Clinical trials: Vascular Access
Postoperative Hemorrhage
Neptune Pad ® Compared to Conventional Manual Compression
BACKGROUND. Arterial access site complications remain the most frequent adverse events after percutaneous transluminal procedures.
- Trial name
- NCT00597363
- Testing
- Neptune P.A.D. (R), conventional manual compression
- Where
- Austria
- Volunteers
- 201 people
- Sponsor
- Vienna General Hospital
Vascular Access Complication
Effectiveness of the Rapid Intravascular Start (RIVS) System Versus Conventional Catheter
The study will test a hypothesis that the RIVS system will have a higher rate of successful first PIV placement compared to conventional catheter without a significant increase in complications and time of procedure.
- Trial name
- NCT00914069
- Testing
- RIVS vascular access, Conventional vascular access
- Where
- 3 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Patent Foramen Ovale, Stroke
PFO ACCESS Registry
Closure of Patent Foramen Ovale with the AMPLATZER® PFO OCCLUDER in patients with at least two cryptogenic strokes due to presumed paradoxical embolism through a patent foramen ovale and who have failed conventional therapy.
- Trial name
- NCT00583401
- Testing
- Device closure with the AMPLATZER PFO Occluder
- Sponsor
- Abbott Medical Devices
Vascular Access Devices
Tunneled Hemodialysis Catheters as Permanent Vascular Access: Evaluating One-year Patency Rate and Affecting Factors
In this prospective cross-sectional study, patients with ESRD unfit for AVF/AVG were scheduled for a right or left trans-jugular tunneled catheter placement.
- Trial name
- NCT06355466
- Where
- Iran
- Volunteers
- 156 people
- Sponsor
- Golestan University of Medical sciences
Proteus Syndrome, PIK3CA-Related Overgrowth Spectrum (PROS)
Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies
ARQ 092 is being investigated for patients with overgrowth diseases and/or vascular anomalies with genetic alterations of the PI3K/AKT pathway and may be available for patients who are ineligible for an ongoing ARQ 092 clinical…
- Conditions
- Proteus Syndrome, PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorders
- Trial name
- NCT03317366
- Testing
- ARQ 092
- Sponsor
- ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
Meningioma
ITM11 Expanded Access Program
This Expanded Access Program (EAP) is intended to provide eligible participants with access to ITM-11 prior to approval by local regulatory authorities. Program availability is subject to country eligibility.
- Trial name
- NCT07497984
- Testing
- ITM-11
- Sponsor
- ITM Solucin GmbH
Portal Hypertension, Liver Diseases
Achieving Portal Access With Scorpion Post-Approval Study 2
Creation of the parenchymal tract between the portal vein and the hepatic vein is the most difficult and time consuming step in a TIPS procedure.
- Conditions
- Portal Hypertension, Liver Diseases, Ascites Hepatic, Hydrothorax
- Trial name
- APASS2 (NCT06856655)
- Testing
- Scorpion Portal Vein Access Kit
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Argon Medical Devices
Hereditary Angioedema
Expanded Access Program With Lanadelumab for Japanese People With Hereditary Angioedema
The expanded access program allows people to gain access to an unlicensed treatment on compassionate grounds. Lanadelumab, also known as TAK-743, is a medicine to help prevent hereditary angioedema attacks.
- Trial name
- NCT04687137
- Testing
- TAK-743 300 mg
- Where
- 9 sites in Japan
- Volunteers
- 12 people
- Sponsor
- Takeda
Aortic Stenosis, Coronary Artery Disease
Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS)
With the upcoming expansion of transcatheter aortic valve replacement (TAVR) indications to younger patients, the feasibility of coronary ostia cannulation beyond different bioprosthesis stent is currently a matter of debate.
- Trial name
- RE-ACCESS (NCT04026204)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Catania
Vascular Access Complication
Central Line Placement-EVALUATION OF LINE DEPTH AS A FACTOR IN NEED FOR LINE REPLACEMENT SECONDARY TO MALPOSITION
This is a single center, randomized, controlled trial in which tunneled central line catheters will be placed in two distinct, select positions.
- Trial name
- NCT02602665
- Testing
- Shallow catheter tip placement, Deep catheter tip placement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Sturge-Weber Syndrome
Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome
The purpose of this study is to determine the tolerability and optimal dose of cannabidiol (CBD) as an simultaneous treatment in children and young adults with Sturge-Weber syndrome (SWS) and drug resistant epilepsy.
- Trial name
- NCT02332655
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Anne Comi, MD
Fabry Disease
Physician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry Disease
This program allows physicians to request permission from Amicus Therapeutics (Amicus) for treatment access to migalastat hydrochloride (HCl) for specific patients with Fabry disease. Treatment is open label.
- Trial name
- NCT01476163
- Testing
- migalastat HCl 150 mg, migalastat HCl 20 mg
- Sponsor
- Amicus Therapeutics
Hereditary Angioedema, HAE
Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies
This is a phase 3b open-label study providing access to berotralstat for HAE patients who were previously enrolled in berotralstat studies.
- Trial name
- APeX-A (NCT04933721)
- Testing
- berotralstat
- Where
- 16 sites in Canada, Czechia and 9 more
- Volunteers
- 139 people
- Sponsor
- BioCryst Pharmaceuticals
Arteriovenous Graft, Arteriovenous Fistula
Validation of Arterio Venous Access Stage (AVAS) Classification
VAVASC trial is an observational multicentre study. The aim of this trial is to validate AVAS (arteriovenous vascular access stage) classification.
- Conditions
- Arteriovenous Graft, Arteriovenous Fistula, Dialysis Access Malfunction, Kidney Failure
- Trial name
- VAVASC (NCT04796558)
- Testing
- AVAS Classification
- Where
- Czechia
- Volunteers
- 800 people
- Sponsor
- Vascular surgery, University hospital Královské Vinohrady, Prague
Thrombosis
Heparin Versus Lepirudin Flushes in Preventing Blockage of Venous Access Devices
This study will compare the effectiveness of two blood thinners, heparin and lepirudin, in preventing withdrawal occlusion (blockage) in a venous access device (VAD).
- Trial name
- NCT00039767
- Testing
- Lepirudin
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Microbial Colonization, Infection, Bacterial
Microorganisms on Reusable Tourniquets
The purpose of this study was to compare microbial contamination on the surface of reusable stasis after indefinite use, 2 weeks and 4 weeks.
- Conditions
- Microbial Colonization, Infection, Bacterial, HAI, Nurse's Role
- Trial name
- NCT06566495
- Testing
- collection of microbiological material from reusable tourniquets
- Where
- Poland
- Volunteers
- 53 people
- Sponsor
- Medical University of Gdansk
Vascular Access Devices, Vascular Access
Impact of a Long Peripheral Venous Catheter Protocol in Pediatric and Neonatal Care
The purpose of this study is to evaluate the impact of a training intervention aimed at nursing personnel on the appropriateness of the indication of long peripheral venous catheters in candidate pediatric and neonatal patients…
- Conditions
- Vascular Access Devices, Vascular Access, Vascular Access Complication
- Trial name
- NCT07870876
- Testing
- Training program on long peripheral catheter insertion
- Volunteers
- 33 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Vascular Access
Accuvein Versus Standard Care for Intravenous Cannulation Procedure in Children
Peripheral intravenous cannulation is one of the most common procedures performed in children admitted to hospital. It is a painful and anxiety-provoking gesture for children with possible memorization of the pain even more…
- Trial name
- AVEn (NCT03427723)
- Testing
- Accuvein®400, Standard care
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atrial Fibrillation, Peripheral Vascular Disease
Ultrasound-guided Femoral Vein Accessibility, Safety and Time for Atrial Fibrillation Treatment
This study is designed to evaluate the use of real-time ultrasound-guided femoral venipuncture during pulmonary vein isolation for treating atrial fibrillation .
- Conditions
- Atrial Fibrillation, Peripheral Vascular Disease, Vascular Access Complications
- Trial name
- ULTRA-FAST (NCT02834221)
- Testing
- Real-time ultrasound-guided puncture, Anatomical landmark guided puncture
- Where
- 4 sites in Czechia, Japan
- Volunteers
- 320 people
- Sponsor
- Kenichiro Yamagata
Catheter Related Blood Stream Infection, Hemodialysis
Antimicrobial Locks for Hemodialysis Catheter Infections
Tunneled hemodialysis catheters are susceptible to infection with high incidence of complication to the hemodialysis patients .The study aimed to prevent catheter infection through comparing use of antimicrobial solution…
- Conditions
- Catheter Related Blood Stream Infection, Hemodialysis, Vascular Access
- Trial name
- NCT07074821
- Testing
- Taurolidine citrate 4% and heparin 500
- Where
- Oman
- Volunteers
- 100 people
- Sponsor
- Oman Ministry of Health