Clinical trials: Visual Acuity, open to volunteers
Retinopathy of Prematurity (ROP), Premature Birth
Long-term Ophthalmic Outcomes in Ex-premature Infants
There is limited knowledge on ophthalmological outcomes in the adult population that was born prematurely. This study aims to evaluate the ophthalmic outcomes of ex-premature infants that have reached adolescence or adulthood.
- Trial name
- LTOO-XP (NCT06649513)
- Testing
- eye drops (Tropicamid)
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Erasmus Medical Center
Retinal Dystrophies, Color Vision Defects
Natural History Study of Inherited Retinal Diseases
This prospective, observational investigation seeks to delineate the interplay between chromatic vision deficits and both functional visual outcomes and anatomical retinal biomarkers in individuals affected by Inherited Retinal…
- Conditions
- Retinal Dystrophies, Color Vision Defects, Vision Disorders, Macular Degeneration
- Trial name
- MojiLVCDT (NCT07085533)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Augelux Therapeutics
Leber Hereditary Optic Disease
Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients
The goal of this Clinical trial is to assess the safety and efficacy of GS010 at two dose levels on visual acuity and retinal mitochondrial activity in patients affected with ND4 Leber Hereditary Optic Neuropathy (LHON)
- Trial name
- REVISE (NCT07303296)
- Testing
- GS010 High dose, GS010 Low dose
- Where
- France
- Volunteers
- 14 people
- Sponsor
- GenSight Biologics
Amblyopia, Amblyopia Unilateral
Valproate for the Treatment of Residual Amblyopia
The goal of this clinical trial is to determine the efficacy of valproate as an adjunct therapy to treat amblyopia beyond the critical period in children aged 8-17 years who have amblyopia of ≥3 lines of interocular…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- VARA (NCT07226141)
- Testing
- Valproate, Patch
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Boston Children's Hospital
Amblyopia, Amblyopia Unilateral
Non-invasive Induction of Metaplasticity for Amblyopia
The goal of this clinical trial is to determine the efficacy of flicker therapy as an adjunct therapy to treat amblyopia beyond the critical period in adolescents and adults aged 14-40 years who have amblyopia of ≥3 lines of…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- NIMA (NCT07846397)
- Testing
- Flicker
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Amblyopia, Amblyopia Strabismic
Effectiveness of tDCS in Paediatric Amblyopia.
The goal of this randomized, double-blind clinical trial is to determine whether transcranial direct current stimulation (tDCS) can effectively and safely improve vision in children aged 4-14 years with strabismic or…
- Conditions
- Amblyopia, Amblyopia Strabismic, Visual Acuity, Stereoscopic Vision
- Trial name
- tDCS (NCT07547670)
- Testing
- tDCS
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad de Murcia
Macular Dystrophy
Correlation Between OCT and Mf-ERG Findings With BCVA in Patients With Macular Dystrophy
Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity in patients with macular dystrophy.
- Trial name
- NCT07171541
- Testing
- OCT ,mFERG,VA test
- Volunteers
- 30 people
- Sponsor
- New Valley University
Myopia, Visual Rehabilitation
Exploring Perceptual Learning in Blurred Gabor Discrimination for Low-Myopic Children
This exploratory study investigates whether perceptual learning using blurred Gabor stimuli can improve uncorrected distance visual acuity in children aged 6-10 years with low myopia.
- Conditions
- Myopia, Visual Rehabilitation, Perceptual Learning
- Trial name
- NCT07107646
- Testing
- vision training system, VTS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Ophthalmic Disorders
Co-designing and Evaluating a Real-world Implementation Model for Remote Consultation with Vision Self-testing.
This study aims to involve the public, patients and National Health Service (NHS) staff in co-designing a scalable, inclusive and sustainable implementation model for ophthalmic remote consultation with vision self-testing (the…
- Trial name
- ReVise (NCT05941182)
- Testing
- online questionnaires
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Monochromatic, L- and S-cone Modulation Only
Evaluating How Well Different Types of Light-sensitive Cells in the Eye Contribute to Its Focusing Ability
In this experiment, subjects will view shapes on a screen with varying colors and be asked to focus their eyes on the shapes. The shapes will look as though they are jumping to random distances away from the eye.
- Conditions
- Monochromatic, L- and S-cone Modulation Only, L- and M-cone Modulation Only, M and S-cone Modulation Only
- Trial name
- NCT07691463
- Testing
- Color
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
Retinopathy of Prematurity
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)
Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime.
- Trial name
- BabySTEPS2 (NCT04995341)
- Testing
- Investigational ultracompact OCT and OCTA system, retinal photographs
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Duke University
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
CLN3
Study With Batten-1 (Miglustat Liquid Formulation) to Treat Ceroid Lipofuscinosis Neuronal 3 (CLN3) Disease
The goal of this open-label, single-arm, multicenter study is to assess the efficacy and safety of Batten-1 (oral liquid formulation of miglustat) (15 mg/kg up to 600 mg/day) in approximately 27 pediatric subjects with CLN3…
- Trial name
- NCT07882290
- Testing
- Miglustat oral liquid formulation (250 mg/mL)
- Where
- 10 sites in United States, Denmark and 6 more
- Volunteers
- 27 people
- Sponsor
- Beyond Batten Disease Foundation
Refractive Error Correction, Visual Acuity
Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome
This study seeks to determine whether glasses prescriptions determined from computer analysis of detailed images of the eyes provide better vision outcomes for children with Down syndrome than prescriptions determined using…
- Trial name
- NCT07490444
- Testing
- Metric-optimized spectacles, Routine Clinical Spectacles
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University