Clinical trials: Vitamin D Insufficiency
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism
This is a phase 3, multi-center, randomized, double-blind, placebo-controlled study in children with stage 3-4 chronic kidney disease (CKD), secondary hyperparathyroidism (SHPT) and vitamin D insufficiency.
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Vitamin d Deficiency, Secondary Hyperparathyroidism
- Trial name
- NCT05543928
- Testing
- CTAP101
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- OPKO Health, Inc.
Irritable Bowel Syndrome (IBS), Vitamin D Deficiency
Role of Vitamin D Supplementation in Children With Irritable Bowel Syndrome
This study was designed to determine whether vitamin D supplementation improved symptoms in children with irritable bowel syndrome, a condition associated with repeated abdominal pain and changes in bowel habits.
- Trial name
- NCT07914478
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aziz Bhatti Shaheed Teaching Hospital
Vitamin D Deficiency, Cystic Fibrosis
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF
Cystic fibrosis (CF) is an autosomal recessive disease caused by alterations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, characterized by multisystemic alterations, mainly in the lung, intestine…
- Conditions
- Vitamin D Deficiency, Cystic Fibrosis, Bone Density, Low, Inflammation Chronic
- Trial name
- NCT05276960
- Testing
- Cholecalciferol Pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
End Stage Renal Disease, Hyperparathyroidism, Secondary
Mineral and Bone Disorders Outcomes in Stage 5D of Chronic Kidney Disease
The MBD-5D is a prospective observational study with a case-cohort and a cohort design. Eligible patients are receiving hemodialysis and have secondary hyperparathyroidism.
- Trial name
- MBD-5D (NCT00995163)
- Where
- Japan
- Volunteers
- 8,020 people
- Sponsor
- Kyowa Kirin Co., Ltd.
End Stage Renal Disease
Effect of Vitamin K 2 on Vascular Calcification in Hemodialysis Patients
The aim of this study is to assess the effect of supplementation of vitamin K2 (menaquinone, MK-7) and cholecalciferol (inactive vitamin D) on circulating levels of calcification regulators and to assess their safety in pediatric…
- Trial name
- NCT04145492
- Testing
- Vitamin K2, Cholecalciferol (inactive vitamin D), Vitamin K2 and Cholecalciferol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Vitamin D2 Supplementation in Vitamin D Insufficiency
Optimal Doses of Ergocalciferol Supplementation for Treatment of Hypovitaminosis D in Adults
To investigate the optimal initial and maintenance doses of vitamin D2 supplementation for the treatment of vitamin D insufficiency in Thai adults, and to determine the prevalence of and risk factors for hypovitaminosis D among…
- Trial name
- NCT03228862
- Testing
- Ergocalciferol
- Where
- Thailand
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Secondary Hyperparathyroidism, End-Stage Renal Disease
Study to Evaluate Safety of Vitamin D Receptor Activators in Patients Ages 0 to 16 With Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis Within Current Clinical Practice
The objective of this study was to observe the safety of paricalcitol utilization in pediatric participants (ages 0 to 16 years old) being treated for secondary hyperparathyroidism (SHPT).
- Trial name
- NCT01134315
- Testing
- Paricalcitol, Calcitriol
- Where
- 18 sites in United States
- Volunteers
- 61 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Bone Disorder, Chronic Kidney Diseases
Effect of Active Vitamin D and Etelcalcetide on Human Osteoclasts in Patients With Chronic Kidney Disease
The optimal management of mineral and bone disorders associated to chronic kidney disease (CKD-MBD) is a daily challenge for nephrologists.
- Trial name
- RENOCLASTE (NCT03527511)
- Testing
- Measure of etecalcetide on osteoclastic biology
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease, Renal Transplantation
Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.
Vitamin D is not seen anymore only as a phosphocalcic and bone hormone, but also as having an effect on global health (anti-infective, anti-inflammatory, anti-tumour roles and cardiovascular protection).
- Conditions
- Chronic Kidney Disease, Renal Transplantation, Nephrotic Syndrome
- Trial name
- VITATOL (NCT02238418)
- Testing
- Cholecalciferol vial (100 000 UI)
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Anemia of Chronic Kidney Disease
Vitamin D as a Modifier of Serum Hepcidin in Children With Chronic Kidney Disease
This research is being done to study the effectiveness of vitamin D (cholecalciferol) to modify hepcidin levels in children with chronic kidney disease (CKD). Anemia is a common problem in children with CKD.
- Trial name
- D-fense (NCT01532349)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder
Chinese CKD-MBD Prevalence Survey (CRISS-MBD)
This is a multi-center cross sectional epidemiological study. The purpose of this study is to investigate the prevalence of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) in Chinese population.
- Trial name
- NCT04714918
- Where
- 40 sites in China
- Volunteers
- 10,254 people
- Sponsor
- Limeng Chen
Vitamin-D Insufficiency
Seasonal Variations in Serum 25-hydroxy Vitamin-D Levels in a Swedish Cohort
The purpose of this study was to study seasonal inter-individual and intra-individual variations in S-25(OH)D and to explore parameters associated with S-25-OHD in healthy Swedish adults.
- Trial name
- NCT02136407
- Where
- Sweden
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Asthma
Vitamin D and Severe Asthma Exacerbations
This study of vitamin D is designed to assess both the safety and efficacy of potential doses (2,000 IU/day and 4,000 IU/day) in raising a vitamin D level to a normal range in a short period of time (e.g.
- Trial name
- SAVED-P (NCT01921894)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh
Vitamin D 25-Hydroxylase Deficiency, Vitamin D Deficiency/Insufficiency
Effects of High-Dose Vitamin D on Hormones, Neuromuscular Function, Cognition, and Body Composition in Athletes
This study aims to evaluate the effects of high-dose vitamin D3 supplementation on selected physiological, neuromuscular, and cognitive parameters in athletes.
- Trial name
- NCT07641075
- Testing
- Vitamin D supplementation
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Renal Osteodystrophy, End Stage Renal Disease
Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis
OBJECTIVES: I. Evaluate the separate and combined skeletal effects of recombinant human growth hormone (GH) and calcitriol in patients with adynamic renal osteodystrophy. II.
- Trial name
- NCT00004340
- Testing
- calcitriol, growth hormone
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- National Center for Research Resources (NCRR)
Chronic Kidney Disease
Two Vitamin D Dosing Strategies in Children With Chronic Kidney Disease
Vitamin D deficiency is common in the general population and more common in children with chronic kidney disease. Vitamin D is very important for bone health, especially in children with chronic kidney disease.
- Trial name
- NCT01909115
- Testing
- 1000 IU of Vitamin D3, 4000 IU of Vitamin D3
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Emory University
Vitamin D Deficiency
Treatment of Vitamin D Insufficiency
The purpose of this study is to answer the following questions: Does vitamin D increase calcium absorption, bone mass and muscle mass and function in women past menopause who have mildly low vitamin D levels? Do these benefits…
- Trial name
- NCT00933244
- Testing
- High Dose Vitamin D3, Low Dose Vitamin D3
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vitamin D Deficiency
The Effect of Vitamin D on Bone Accretion and Turn-Over in Young Girls
Objectives To evaluate the effect of increased vitamin D intake on vitamin D status, bone mass and bone turnover in young girls aged 12-13.
- Trial name
- NCT00267540
- Testing
- cholecalciferol (D3) (vitamin)
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Asthma, Vitamin D Deficiency
Vitamin D Deficiency and Asthma Exacerbation
The study aim is in two phases. First phase: to evaluate the influence of vitamin D deficiency on asthma severity, degree of airway obstruction and frequency of asthma exacerbations.
- Conditions
- Asthma, Vitamin D Deficiency, Disease Exacerbation
- Trial name
- AVD (NCT02661191)
- Testing
- oral cholecalciferol
- Volunteers
- 119 people
- Sponsor
- University of Turin, Italy